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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

S1P1 inhibits sprouting angiogenesis during vascular development

Authors:
Ben Shoham A, Malkinson G, Krief S, Shwartz Y, Ely Y, Ferrara N, Yaniv K, Zelzer E
Citation:
Development. 2012 Oct;139(20):3859-69. Epub 2012 Sep 5
Epub:
Not Epub
Abstract:
Coordination between the vascular system and forming organs is essential for proper embryonic development. The vasculature...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ben Shoham A, Malkinson G, Krief S, Shwartz Y, Ely Y, Ferrara N, Yaniv K, Zelzer E. S1P1 inhibits sprouting angiogenesis during vascular development. Development. 2012 Oct;139(20):3859-69. Epub 2012 Sep 5.

Exon skipping restores dystrophin expression, but fails to prevent disease progression in later stage dystrophic dko mice

Authors:
Wu C, Cloer C, Lu P, Milazi S, Shaban M, Shah SN, Marston-Poe L, Moulton HM, Lu QL
Citation:
Gene Ther. 2014;[Epub ahead of print] doi:10.1038/gt.2014.53
Epub:
Yes
Abstract:
Antisense therapy with both chemistries of phosphorodiamidate morpholino oligomers (PMOs) and 2′-O-methyl phosphorothioate has...
Delivery Method:
injection
Organism or Cell Type:
utrophin-dystrophin double KO mice
Citation Extract:
Wu C, Cloer C, Lu P, Milazi S, Shaban M, Shah SN, Marston-Poe L, Moulton HM, Lu QL. Exon skipping restores dystrophin expression, but fails to prevent disease progression in later stage dystrophic dko mice. Gene Ther. 2014;[Epub ahead of print] doi:10.1038/gt.2014.53 .

Distinct Innate Immune Phagocyte Responses to Aspergillus fumigatus Conidia and Hyphae in Zebrafish Larvae

Authors:
Knox BP, Deng Q, Rood M, Eickhoff JC, Keller NP, Huttenlocher A
Citation:
Eukaryot Cell. 2014 Oct;13(10):1266-77. doi: 10.1128/EC.00080-14. Epub 2014 May 30.
Epub:
Yes
Abstract:
Aspergillus fumigatus is the most common filamentous fungal pathogen of immunocompromised hosts resulting in invasive...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Knox BP, Deng Q, Rood M, Eickhoff JC, Keller NP, Huttenlocher A. Distinct Innate Immune Phagocyte Responses to Aspergillus fumigatus Conidia and Hyphae in Zebrafish Larvae. Eukaryot Cell. 2014 Oct;13(10):1266-77. doi: 10.1128/EC.00080-14. Epub 2014 May 30..

miR-203 regulates progenitor cell proliferation during adult zebrafish retina regeneration

Authors:
Rajaram K, Harding RL, Hyde DR, Patton JG
Citation:
Dev Biol. 2014 May 20. pii: S0012-1606(14)00260-7. doi: 10.1016/j.ydbio.2014.05.005. [Epub ahead of print]
Epub:
Yes
Abstract:
Damage of the zebrafish retina triggers a spontaneous regeneration response that is initiated by Müller Glia (MG)...
Delivery Method:
injected then electroporated
Organism or Cell Type:
zebrafish
Citation Extract:
Rajaram K, Harding RL, Hyde DR, Patton JG. miR-203 regulates progenitor cell proliferation during adult zebrafish retina regeneration. Dev Biol. 2014 May 20. pii: S0012-1606(14)00260-7. doi: 10.1016/j.ydbio.2014.05.005. [Epub ahead of print].

Hydrogen sulfide inhibits Na+ uptake in larval zebrafish, Danio rerio

Authors:
Kumai Y, Porteus CS, Kwong RW, Perry SF
Citation:
Pflugers Arch. 2014 Jun 18. [Epub ahead of print]
Epub:
Yes
Abstract:
The present study investigated the role of hydrogen sulfide (H2S) in regulating Na+ uptake in larval zebrafish, Danio rerio....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kumai Y, Porteus CS, Kwong RW, Perry SF. Hydrogen sulfide inhibits Na+ uptake in larval zebrafish, Danio rerio. Pflugers Arch. 2014 Jun 18. [Epub ahead of print].

Functional characterization of Prickle2 and BBS7 identify overlapping phenotypes yet distinct mechanisms

Authors:
Mei X, Westfall TA, Zhang Q, Sheffield VC, Bassuk AG, Slusarski DC
Citation:
Dev Biol. 2014 Jun 2. pii: S0012-1606(14)00276-0. doi: 10.1016/j.ydbio.2014.05.020. [Epub ahead of print]
Epub:
Yes
Abstract:
Ciliopathies are genetic disorders that are caused by dysfunctional cilia and affect multiple organs. One type of ciliopathy,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mei X, Westfall TA, Zhang Q, Sheffield VC, Bassuk AG, Slusarski DC. Functional characterization of Prickle2 and BBS7 identify overlapping phenotypes yet distinct mechanisms. Dev Biol. 2014 Jun 2. pii: S0012-1606(14)00276-0. doi: 10.1016/j.ydbio.2014.05.020. [Epub ahead of print].

RNAi-Mediated Gene silencing in Zebrafish Triggered by Convergent Transcription

Authors:
Andrews OE, Cha DJ, Wei C, Patton JG
Citation:
Sci Rep. 2014 Jun 9;4:5222. doi: 10.1038/srep05222
Epub:
Not Epub
Abstract:
RNAi based strategies to induce gene silencing are commonly employed in numerous model organisms but have not been extensively...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Andrews OE, Cha DJ, Wei C, Patton JG. RNAi-Mediated Gene silencing in Zebrafish Triggered by Convergent Transcription. Sci Rep. 2014 Jun 9;4:5222. doi: 10.1038/srep05222.

Transcriptome analysis of Rpl11-deficient zebrafish model of Diamond-Blackfan Anemia

Authors:
Zhang Z, Jia H, Zhang Q, Wan Y, Song B, Jia Q, Liu H, Zhu X, Fang A
Citation:
Genomics Data. 2014;[Epub ahead of print] doi:10.1016/j.gdata.2014.06.008
Epub:
Not Epub
Abstract:
To comprehensively reflect the roles of Rpl11 on the transcriptome of zebrafish model of Diamond-Blackfan Anemia (DBA), we...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Z, Jia H, Zhang Q, Wan Y, Song B, Jia Q, Liu H, Zhu X, Fang A. Transcriptome analysis of Rpl11-deficient zebrafish model of Diamond-Blackfan Anemia. Genomics Data. 2014;[Epub ahead of print] doi:10.1016/j.gdata.2014.06.008.

Left-Right Organizer Flow Dynamics: How Much Cilia Activity Reliably Yields Laterality?

Authors:
Sampaio P, Ferreira RR, Guerrero A, Pintado P, Tavares B, Amaro J, Smith AA, Montenegro-Johnson T, Smith DJ, Lopes SS
Citation:
Dev Cell. 2014 Jun 11. pii: S1534-5807(14)00277-9. doi: 10.1016/j.devcel.2014.04.030. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Internal organs are asymmetrically positioned inside the body. Embryonic motile cilia play an essential role in this process by...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sampaio P, Ferreira RR, Guerrero A, Pintado P, Tavares B, Amaro J, Smith AA, Montenegro-Johnson T, Smith DJ, Lopes SS. Left-Right Organizer Flow Dynamics: How Much Cilia Activity Reliably Yields Laterality?. Dev Cell. 2014 Jun 11. pii: S1534-5807(14)00277-9. doi: 10.1016/j.devcel.2014.04.030. [Epub ahead of print].

The Evolution and Appearance of C3 Duplications in Fish Originate an Exclusive Teleost c3 Gene Form with Anti-Inflammatory Activity

Authors:
Forn-Cuní G, Reis ES, Dios S, Posada D, Lambris JD, Figueras A, Novoa B
Citation:
PLoS ONE. 2014;9(6):e99673. doi:10.1371/journal.pone.0099673
Epub:
Not Epub
Abstract:
The complement system acts as a first line of defense and promotes organism homeostasis by modulating the fates of diverse...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Forn-Cuní G, Reis ES, Dios S, Posada D, Lambris JD, Figueras A, Novoa B. The Evolution and Appearance of C3 Duplications in Fish Originate an Exclusive Teleost c3 Gene Form with Anti-Inflammatory Activity. PLoS ONE. 2014;9(6):e99673. doi:10.1371/journal.pone.0099673.

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