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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12455 scientific papers returned from the database with the search filters currently being used below.

Mutation of beta-tubulin 4B gene (TUBB4B) causes autosomal dominant retinitis pigmentosa with sensorineural hearing loss in a multigenerational family

Authors:
Gregory-Evans CY, Joe AW, Gregory-Evans K
Citation:
Molecular Vision 2025; 31:175-188. Published 16 May 2025
Epub:
Not Epub
Abstract:
Purpose: Members of a multigenerational Canadian family presented to an inherited retinal degeneration (IRD) clinic with...
Link:
http://www.molvis.org/molvis/v31/175/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gregory-Evans CY, Joe AW, Gregory-Evans K. Mutation of beta-tubulin 4B gene (TUBB4B) causes autosomal dominant retinitis pigmentosa with sensorineural hearing loss in a multigenerational family. Molecular Vision 2025; 31:175-188. Published 16 May 2025.

TTC21B variants disrupt the left-right asymmetry and pronephric development in zebrafish

Authors:
Deng L, Yang Y, Yin X, Yang J, Duan Y, Wang K, Duan W, Zhang Y, Xiong B, Zhou J
Citation:
Genes & Diseases, 2025, 101709, ISSN 2352-3042, https://doi.org/10.1016/j.gendis.2025.101709
Epub:
Not Epub
Abstract:
Nephronophthisis (NPHP) is an autosomal recessive kidney disease and is the most prevalent monogenic cause of end-stage renal...
Link:
https://www.sciencedirect.com/science/article/pii/S2352304225001989
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Deng L, Yang Y, Yin X, Yang J, Duan Y, Wang K, Duan W, Zhang Y, Xiong B, Zhou J. TTC21B variants disrupt the left-right asymmetry and pronephric development in zebrafish. Genes & Diseases, 2025, 101709, ISSN 2352-3042, https://doi.org/10.1016/j.gendis.2025.101709.

Zebrafish sall1a and sall4 contribute to body elongation

Authors:
Kawakami H, Bailey A, Gavin E, Gearhart MD, Isabella AJ, Kawakami Y. Kawakami H, Bailey A, Gavin E, Gearhart MD, Isabella AJ, Kawakami Y
Citation:
Dev Biol. 2025 Jun 5:S0012-1606(25)00165-4. doi: 10.1016/j.ydbio.2025.06.006. Epub ahead of print. PMID: 40482694
Epub:
Not Epub
Abstract:
Vertebrate embryos elongate the body after gastrulation. Unlike in mice, which elongate both the trunk and tail after...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0012160625001654
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kawakami H, Bailey A, Gavin E, Gearhart MD, Isabella AJ, Kawakami Y. Kawakami H, Bailey A, Gavin E, Gearhart MD, Isabella AJ, Kawakami Y. Zebrafish sall1a and sall4 contribute to body elongation. Dev Biol. 2025 Jun 5:S0012-1606(25)00165-4. doi: 10.1016/j.ydbio.2025.06.006. Epub ahead of print. PMID: 40482694.

Translation suppresses exogenous target RNA-mediated microRNA decay

Authors:
Li T, Li L, Hiers NM, Sheng P, Wang Y, Traugot CM, Effinger-Morris JF, Akaphan P, Liu Y, Bian J, Fujii K, Xie M
Citation:
Nat Commun. 2025 Jun 6;16(1):5257. doi: 10.1038/s41467-025-60374-4. PMID: 40480978; PMCID: PMC12144122
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) interact with the target mRNAs to induce translational repression and mRNA degradation. Interestingly,...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12144122/
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: HEK293T and mouse striatal cell model of Huntington's Disease
Citation Extract:
Li T, Li L, Hiers NM, Sheng P, Wang Y, Traugot CM, Effinger-Morris JF, Akaphan P, Liu Y, Bian J, Fujii K, Xie M. Translation suppresses exogenous target RNA-mediated microRNA decay. Nat Commun. 2025 Jun 6;16(1):5257. doi: 10.1038/s41467-025-60374-4. PMID: 40480978; PMCID: PMC12144122.

Migration of Kupffer's vesicle derived cells is essential for tail morphogenesis in zebrafish embryos

Authors:
Hoeksma J, den Hertog J
Citation:
Development. 2025 Jun 11:dev.204791. doi: 10.1242/dev.204791. Epub ahead of print. PMID: 40495676
Epub:
Not Epub
Abstract:
A phenotypic screen of fungal filtrates on developing zebrafish embryos identified metabolites from the fungus Ceratocystis...
Link:
https://journals.biologists.com/dev/article/doi/10.1242/dev.204791/368249/Migration-of-Kupffer-s-vesicle-derived-cells-is
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hoeksma J, den Hertog J. Migration of Kupffer's vesicle derived cells is essential for tail morphogenesis in zebrafish embryos. Development. 2025 Jun 11:dev.204791. doi: 10.1242/dev.204791. Epub ahead of print. PMID: 40495676.

Mongolian medicine Eerdun-Wurile promotes myocardial regeneration by regulating MVDA in zebrafish

Authors:
Chen X, Li X, Sun J, Lin Y, Li Y, Lv X, Zhao R, Gu X, Wang W, Xie Y, Xie W, Bade R, Jiang S, Liu X, Zou B, Bi Y, Shao G, Bai H, Zhu W, Jia X
Citation:
Cell Regen. 2025 Jun 6;14(1):22. doi: 10.1186/s13619-025-00235-z. PMID: 40478315; PMCID: PMC12143999
Epub:
Not Epub
Abstract:
Myocardial infarction (MI) is a leading cause of death and disability worldwide. The promotion of myocardial regeneration is a...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12143999/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen X, Li X, Sun J, Lin Y, Li Y, Lv X, Zhao R, Gu X, Wang W, Xie Y, Xie W, Bade R, Jiang S, Liu X, Zou B, Bi Y, Shao G, Bai H, Zhu W, Jia X. Mongolian medicine Eerdun-Wurile promotes myocardial regeneration by regulating MVDA in zebrafish. Cell Regen. 2025 Jun 6;14(1):22. doi: 10.1186/s13619-025-00235-z. PMID: 40478315; PMCID: PMC12143999.

Notoginsenoside R2 attenuates hepatic fibrosis via STAT3-dependent hepatic stellate cells senescence induction and inflammatory microenvironment suppression

Authors:
Deng K, Li M, Li Y, Xiang L, Wang Y, Shi H, Cheng J, Huang S, Lv Z
Citation:
Journal of Ginseng Research, 2025, ISSN 1226-8453, https://doi.org/10.1016/j.jgr.2025.05.007
Epub:
Not Epub
Abstract:
Background Hepatic fibrosis (HF) continues to be a significant global health concern, substantially contributing to morbidity...
Link:
https://www.sciencedirect.com/science/article/pii/S1226845325000685
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Deng K, Li M, Li Y, Xiang L, Wang Y, Shi H, Cheng J, Huang S, Lv Z. Notoginsenoside R2 attenuates hepatic fibrosis via STAT3-dependent hepatic stellate cells senescence induction and inflammatory microenvironment suppression. Journal of Ginseng Research, 2025, ISSN 1226-8453, https://doi.org/10.1016/j.jgr.2025.05.007.

Genetic compensation response contributes to Pleurodeles waltl limb regeneration

Authors:
Yin B, Yu C, Liu Y, Cai H, Wu W, Ye T, Wang L, Xiao L, Zhu Y, Guo H, Zhang K, Wang H
Citation:
NPJ Regen Med. 2025 May 31;10(1):25. doi: 10.1038/s41536-025-00417-y. PMID: 40450023; PMCID: PMC12126524
Epub:
Not Epub
Abstract:
Hippo-Yap/Taz pathway is essential for tissue regeneration in multiple species. However, we found that in the highly...
Link:
https://www.nature.com/articles/s41536-025-00417-y
Delivery Method:
injection by glass microcapillaries and PV830 PicoPump followed by electroporation
Organism or Cell Type:
Pleurodeles waltl (Iberian ribbed newt)
Citation Extract:
Yin B, Yu C, Liu Y, Cai H, Wu W, Ye T, Wang L, Xiao L, Zhu Y, Guo H, Zhang K, Wang H. Genetic compensation response contributes to Pleurodeles waltl limb regeneration. NPJ Regen Med. 2025 May 31;10(1):25. doi: 10.1038/s41536-025-00417-y. PMID: 40450023; PMCID: PMC12126524.

Targeting the CD47/thrombospondin-1 signaling axis regulates immune cell bioenergetics in the tumor microenvironment to potentiate antitumor immune response

Authors:
Stirling ER, Terabe M, Wilson AS, Kooshki M, Yamaleyeva LM, Alexander-Miller MA, Zhang W, Miller LD, Triozzi PL, Soto-Pantoja DR
Citation:
J Immunother Cancer. 2022 Nov;10(11):e004712. doi: 10.1136/jitc-2022-004712. PMID: 36418073; PMCID: PMC9685258
Epub:
Not Epub
Abstract:
Background: CD47 is an integral membrane protein that alters adaptive immunosurveillance when bound to the matricellular...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC9685258/
Delivery Method:
Endo-Porter for cells, intraperitoneal (i.p.) for mice
Organism or Cell Type:
Pmel-1 CD8+ T cells; C57Bl/6 mice with B16 melanoma tumor explants
Citation Extract:
Stirling ER, Terabe M, Wilson AS, Kooshki M, Yamaleyeva LM, Alexander-Miller MA, Zhang W, Miller LD, Triozzi PL, Soto-Pantoja DR. Targeting the CD47/thrombospondin-1 signaling axis regulates immune cell bioenergetics in the tumor microenvironment to potentiate antitumor immune response. J Immunother Cancer. 2022 Nov;10(11):e004712. doi: 10.1136/jitc-2022-004712. PMID: 36418073; PMCID: PMC9685258.

A light-regulated circadian timer optimizes neutrophil bactericidal activity to boost daytime immunity

Authors:
Du LY, Keerthisinghe P, Rolland L, Sung YJ, Darroch H, Linnerz T, Ashimbayeva E, Grant MJ, Kakadia PM, Ramachandran A, Tups A, Spaink HP, Bohlander SK, Cheeseman J, Crosier PS, Astin JW, Warman G, Hall CJ
Citation:
Sci Immunol. 2025 May 23;10(107):eadn3080. doi: 10.1126/sciimmunol.adn3080. Epub 2025 May 23. PMID: 40408429
Epub:
Not Epub
Abstract:
The immune response exhibits strong circadian rhythmicity, with enhanced bacterial clearance often synchronized with an...
Link:
https://www.science.org/doi/10.1126/sciimmunol.adn3080
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Du LY, Keerthisinghe P, Rolland L, Sung YJ, Darroch H, Linnerz T, Ashimbayeva E, Grant MJ, Kakadia PM, Ramachandran A, Tups A, Spaink HP, Bohlander SK, Cheeseman J, Crosier PS, Astin JW, Warman G, Hall CJ. A light-regulated circadian timer optimizes neutrophil bactericidal activity to boost daytime immunity. Sci Immunol. 2025 May 23;10(107):eadn3080. doi: 10.1126/sciimmunol.adn3080. Epub 2025 May 23. PMID: 40408429.

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