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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12455 scientific papers returned from the database with the search filters currently being used below.

The human RIF1-Long isoform interacts with BRCA1 to promote recombinational fork repair under DNA replication stress

Authors:
Dong Q, Day M, Saito Y, Parker E, Watts LP, Kanemaki MT, Oliver AW, Pearl LH, Hiraga SI, Donaldson AD
Citation:
Nat Commun. 2025 Jul 1;16(1):5820. doi: 10.1038/s41467-025-60817-y. PMID: 40595496
Epub:
Not Epub
Abstract:
RIF1 is a multifunctional protein that regulates DNA replication and repair. RIF1-deficient cells are hypersensitive to DNA...
Link:
https://www.nature.com/articles/s41467-025-60817-y
Delivery Method:
Endo-Porter PEG
Organism or Cell Type:
hTERT RPE-1 cells
Citation Extract:
Dong Q, Day M, Saito Y, Parker E, Watts LP, Kanemaki MT, Oliver AW, Pearl LH, Hiraga SI, Donaldson AD. The human RIF1-Long isoform interacts with BRCA1 to promote recombinational fork repair under DNA replication stress. Nat Commun. 2025 Jul 1;16(1):5820. doi: 10.1038/s41467-025-60817-y. PMID: 40595496.

Chordin-mediated BMP shuttling patterns the secondary body axis in a cnidarian

Authors:
Mörsdorf D, Prünster MM, Knabl P, Genikhovich G
Citation:
Sci Adv. 2025 Jun 13;11(24):eadu6347. doi: 10.1126/sciadv.adu6347. Epub 2025 Jun 13. PMID: 40512865; PMCID: PMC12164971
Epub:
Not Epub
Abstract:
Bone morphogenetic protein (BMP) signaling patterns secondary body axes throughout Bilateria and in the bilaterally symmetric...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12164971/
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella embryo
Citation Extract:
Mörsdorf D, Prünster MM, Knabl P, Genikhovich G. Chordin-mediated BMP shuttling patterns the secondary body axis in a cnidarian. Sci Adv. 2025 Jun 13;11(24):eadu6347. doi: 10.1126/sciadv.adu6347. Epub 2025 Jun 13. PMID: 40512865; PMCID: PMC12164971.

Genetic compensation in podocalyxin-like mutants during zebrafish liver development

Authors:
Ross AN, Miscik NM, Kalasekar SM, Harris JD, Tran M, Saxena A, Baker SA, Evason KJ
Citation:
2025 eLife14:RP106460.
Epub:
Not Epub
Abstract:
Hepatic stellate cells (HSCs) are critical for normal liver development and regeneration. Podocalyxin-like (podxl) is highly...
Link:
https://elifesciences.org/reviewed-preprints/106460v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ross AN, Miscik NM, Kalasekar SM, Harris JD, Tran M, Saxena A, Baker SA, Evason KJ. Genetic compensation in podocalyxin-like mutants during zebrafish liver development. 2025 eLife14:RP106460. .

Ciliary and non-ciliary functions of CEP104 in Xenopus

Authors:
Louka P, Potamiti L, Panayiotidis MI, Skourides PA
Citation:
bioRxiv [preprint] 2025.06.12.659327; doi: https://doi.org/10.1101/2025.06.12.659327
Epub:
Not Epub
Abstract:
Cep104 is a conserved protein essential for centriole and cilia function, with mutations linked to Joubert Syndrome. We...
Link:
https://www.biorxiv.org/content/10.1101/2025.06.12.659327v2.full
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Louka P, Potamiti L, Panayiotidis MI, Skourides PA. Ciliary and non-ciliary functions of CEP104 in Xenopus. bioRxiv [preprint] 2025.06.12.659327; doi: https://doi.org/10.1101/2025.06.12.659327.

High-Throughput Screening Identifies Bisphenol P as a Potent Cardiotoxin, Inducing Cardiotoxicity through Apoptosis and the NF-κB Pathway

Authors:
Wang J, Magnuson JT, Feng Y, Zhao W, Gao C, Zheng C, Qiu W
Citation:
Environ Sci Technol. 2025 Jul 29;59(29):14870-14880. doi: 10.1021/acs.est.5c00573. Epub 2025 Jun 26. PMID: 40570244
Epub:
Not Epub
Abstract:
The increasing use of plastic additives, particularly bisphenols (BPs), has raised significant concerns about their potential...
Link:
https://pubs.acs.org/doi/10.1021/acs.est.5c00573
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang J, Magnuson JT, Feng Y, Zhao W, Gao C, Zheng C, Qiu W. High-Throughput Screening Identifies Bisphenol P as a Potent Cardiotoxin, Inducing Cardiotoxicity through Apoptosis and the NF-κB Pathway. Environ Sci Technol. 2025 Jul 29;59(29):14870-14880. doi: 10.1021/acs.est.5c00573. Epub 2025 Jun 26. PMID: 40570244.

Foxj3 represses TGF-β signals-responsive transcriptions in Xenopus early development

Authors:
Yoon GH, Kim MS, Choi SC
Citation:
Genes Genomics. 2025 Jun 16. doi: 10.1007/s13258-025-01654-7. Epub ahead of print. PMID: 40522413
Epub:
Not Epub
Abstract:
Background: Forkhead box (Fox) proteins belong to a large family of transcription factors characterized by a highly conserved...
Link:
https://link.springer.com/article/10.1007/s13258-025-01654-7
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Yoon GH, Kim MS, Choi SC. Foxj3 represses TGF-β signals-responsive transcriptions in Xenopus early development. Genes Genomics. 2025 Jun 16. doi: 10.1007/s13258-025-01654-7. Epub ahead of print. PMID: 40522413.

The indispensable role of Mediator complex subunit 27 during neurodevelopment

Authors:
Li X, Yiliyaer N, Guo T, Zhao H, Lei Y, Gu S
Citation:
Cell Biosci. 2025 Jun 16;15(1):83. doi: 10.1186/s13578-025-01425-7. PMID: 40524219; PMCID: PMC12172316
Epub:
Not Epub
Abstract:
Background: MED27 is a subunit of the Mediator complex, a highly conserved protein assembly that initiates transcription by...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12172316/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li X, Yiliyaer N, Guo T, Zhao H, Lei Y, Gu S. The indispensable role of Mediator complex subunit 27 during neurodevelopment. Cell Biosci. 2025 Jun 16;15(1):83. doi: 10.1186/s13578-025-01425-7. PMID: 40524219; PMCID: PMC12172316.

Genetic compensation highlights the importance of neural cell adhesion molecule Ncam1 paralogs in balancing signaling pathways during zebrafish lateral line development

Authors:
Lange A, Bastmeyer M, Bentrop J
Citation:
Eur J Cell Biol. 2025 Jun 19;104(3):151500. doi: 10.1016/j.ejcb.2025.151500. Epub ahead of print. PMID: 40570383
Epub:
Not Epub
Abstract:
The neural cell adhesion molecule NCAM1 is essential for neuronal development and enables organized cell migration, axon growth...
Link:
https://www.sciencedirect.com/science/article/pii/S0171933525000251
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lange A, Bastmeyer M, Bentrop J. Genetic compensation highlights the importance of neural cell adhesion molecule Ncam1 paralogs in balancing signaling pathways during zebrafish lateral line development. Eur J Cell Biol. 2025 Jun 19;104(3):151500. doi: 10.1016/j.ejcb.2025.151500. Epub ahead of print. PMID: 40570383.

Antisense Oligonucleotides Targeting the SARS-CoV-2 Nucleocapsid Gene Decrease Viral Titers in Hamsters

Authors:
Fitzpatrick C, Meunier N, Lepoder S, Dhorne-Pollet S, Da Costa B, Klonjkowki B, Eléouët J-F, Burzio VA, Delmas B, Barrey E
Citation:
Molecular Therapy - Nucleic Acids (2025)
Epub:
Not Epub
Abstract:
SARS-CoV-2 is a positive, single-stranded RNA coronavirus responsible for the COVID-19 pandemic. The emergence of new variants...
Link:
https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(25)00166-0
Delivery Method:
Lipofectamine 2000 for cell culture; intranasal for hamsters
Organism or Cell Type:
cell culture: HEK-293T/ACE2; in vivo: Syrian hamsters
Citation Extract:
Fitzpatrick C, Meunier N, Lepoder S, Dhorne-Pollet S, Da Costa B, Klonjkowki B, Eléouët J-F, Burzio VA, Delmas B, Barrey E. Antisense Oligonucleotides Targeting the SARS-CoV-2 Nucleocapsid Gene Decrease Viral Titers in Hamsters. Molecular Therapy - Nucleic Acids (2025).

New facets of zona pellucida (ZP) proteins: called oocyte-specific, yet produced by the preimplantation embryo and needed for blastocyst formation

Authors:
Boiani M, Fuellen G, Drexler H, Israel S, Heinrich I, Nolte T
Citation:
Human Reproduction, Volume 40, Issue Supplement_1, June 23, 2025
Epub:
Not Epub
Abstract:
Study question: What does a secreted oocyte-specific protein, ZP2, do inside mouse embryos during cleavage? Summary answer:...
Link:
https://academic.oup.com/humrep/article/40/Supplement_1/deaf097.291/8171200
Delivery Method:
microinjection
Organism or Cell Type:
mouse embryo
Citation Extract:
Boiani M, Fuellen G, Drexler H, Israel S, Heinrich I, Nolte T. New facets of zona pellucida (ZP) proteins: called oocyte-specific, yet produced by the preimplantation embryo and needed for blastocyst formation. Human Reproduction, Volume 40, Issue Supplement_1, June 23, 2025.

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