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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species

Authors:
Xu C, Tabebordbar M, Iovino S, Ciarlo C, Liu J, Castiglioni A, Price E, Liu M, Barton ER, Kahn CR, Wagers AJ, Zon LI
Citation:
Cell. 2013 Nov 7;155(4):909-21. doi: 10.1016/j.cell.2013.10.023
Epub:
Not Epub
Abstract:
Ex vivo expansion of satellite cells and directed differentiation of pluripotent cells to mature skeletal muscle have proved...
Link:
http://www.cell.com/cell/abstract/S0092-8674%2813%2901299-3
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xu C, Tabebordbar M, Iovino S, Ciarlo C, Liu J, Castiglioni A, Price E, Liu M, Barton ER, Kahn CR, Wagers AJ, Zon LI. A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species. Cell. 2013 Nov 7;155(4):909-21. doi: 10.1016/j.cell.2013.10.023.

Autophosphorylation and Pin1 binding coordinate DNA damage-induced HIPK2 activation and cell death

Authors:
Bitomsky N, Conrad E, Moritz C, Polonio-Vallon T, Sombroek D, Schultheiss K, Glas C, Greiner V, Herbel C, Mantovani F, del Sal G, Peri F, Hofmann TG
Citation:
Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):E4203-12. doi: 10.1073/pnas.1310001110. Epub 2013 Oct 21
Epub:
Not Epub
Abstract:
Excessive genome damage activates the apoptosis response. Protein kinase HIPK2 is a key regulator of DNA damage-induced...
Link:
http://www.pnas.org/content/110/45/E4203.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bitomsky N, Conrad E, Moritz C, Polonio-Vallon T, Sombroek D, Schultheiss K, Glas C, Greiner V, Herbel C, Mantovani F, del Sal G, Peri F, Hofmann TG. Autophosphorylation and Pin1 binding coordinate DNA damage-induced HIPK2 activation and cell death. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):E4203-12. doi: 10.1073/pnas.1310001110. Epub 2013 Oct 21.

De novo SOX11 mutations cause Coffin-Siris syndrome

Authors:
Tsurusaki Y, Koshimizu E, Ohashi H, Phadke S, Kou I, Shiina M, Suzuki T, Okamoto N, Imamura S, Yamashita M, Watanabe S, Yoshiura KI, Kodera H, Miyatake S, Nakashima M, Saitsu H, Ogata K, Ikegawa S, Miyake N, Matsumoto N
Citation:
Nat Commun. 2014 Jun 2;5:4011. doi: 10.1038/ncomms5011
Epub:
Not Epub
Abstract:
Coffin-Siris syndrome (CSS) is a congenital disorder characterized by growth deficiency, intellectual disability, microcephaly...
Link:
http://www.nature.com/ncomms/2014/140602/ncomms5011/full/ncomms5011.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tsurusaki Y, Koshimizu E, Ohashi H, Phadke S, Kou I, Shiina M, Suzuki T, Okamoto N, Imamura S, Yamashita M, Watanabe S, Yoshiura KI, Kodera H, Miyatake S, Nakashima M, Saitsu H, Ogata K, Ikegawa S, Miyake N, Matsumoto N. De novo SOX11 mutations cause Coffin-Siris syndrome. Nat Commun. 2014 Jun 2;5:4011. doi: 10.1038/ncomms5011.

Multiple modes of proepicardial cell migration require heartbeat

Authors:
Plavicki JS, Hofsteen P, Yue MS, Lanham KA, Peterson RE, Heideman W
Citation:
BMC Dev Biol. 2014 May 15;14(1):18. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: The outermost layer of the vertebrate heart, the epicardium, forms from a cluster of progenitor cells termed the...
Link:
http://www.biomedcentral.com/1471-213X/14/18/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Plavicki JS, Hofsteen P, Yue MS, Lanham KA, Peterson RE, Heideman W. Multiple modes of proepicardial cell migration require heartbeat. BMC Dev Biol. 2014 May 15;14(1):18. [Epub ahead of print].

Identification of three novel FGF16 mutations in X-linked recessive fusion of the fourth and fifth metacarpals and possible correlation with heart disease

Authors:
Laurell T, Nilsson D, Hofmeister W, Lindstrand A, Ahituv N, Vandermeer J, Amilon A, Annerén G, Arner M, Pettersson M, Jäntti N, Rosberg H-E, Cattini PA, Nordenskjöld A, Mäkitie O, Grigelioniene G, Nordgren A.
Citation:
Mol Genet Genomic Med. 2014:[Epub ahead of print] doi:10.1002/mgg3.81
Epub:
Not Epub
Abstract:
Nonsense mutations in FGF16 have recently been linked to X-linked recessive hand malformations with fusion between the fourth...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/mgg3.81/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Laurell T, Nilsson D, Hofmeister W, Lindstrand A, Ahituv N, Vandermeer J, Amilon A, Annerén G, Arner M, Pettersson M, Jäntti N, Rosberg H-E, Cattini PA, Nordenskjöld A, Mäkitie O, Grigelioniene G, Nordgren A.. Identification of three novel FGF16 mutations in X-linked recessive fusion of the fourth and fifth metacarpals and possible correlation with heart disease. Mol Genet Genomic Med. 2014:[Epub ahead of print] doi:10.1002/mgg3.81.

Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche

Authors:
Carroll KJ, Esain V, Garnaas MK, Cortes M, Dovey MC, Nissim S, Frechette GM, Liu SY, Kwan W, Cutting CC, Harris JM, Gorelick DA, Halpern ME, Lawson ND, Goessling W, North TE
Citation:
Dev Cell. 2014 May 27;29(4):437-53. doi: 10.1016/j.devcel.2014.04.012
Epub:
Not Epub
Abstract:
Genetic control of hematopoietic stem and progenitor cell (HSPC) function is increasingly understood; however, less is known...
Link:
http://www.sciencedirect.com/science/article/pii/S1534580714002329
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Carroll KJ, Esain V, Garnaas MK, Cortes M, Dovey MC, Nissim S, Frechette GM, Liu SY, Kwan W, Cutting CC, Harris JM, Gorelick DA, Halpern ME, Lawson ND, Goessling W, North TE. Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche. Dev Cell. 2014 May 27;29(4):437-53. doi: 10.1016/j.devcel.2014.04.012.

Induced IL-10 Splice Altering Approach to Antiviral Drug Discovery

Authors:
Panchal RG, Mourich DV, Bradfute S, Hauck LL, Warfield KL, Iversen PL, Bavari S
Citation:
Nucleic Acid Ther. 2014;24(3):179-185. doi:10.1089/nat.2013.0457
Epub:
Not Epub
Abstract:
Ebola virus causes an acute hemorrhagic fever lethal in primates and rodents. The contribution of host immune factors to...
Link:
http://online.liebertpub.com/doi/full/10.1089/nat.2013.0457
Delivery Method:
peptide-linked
Organism or Cell Type:
mice
Citation Extract:
Panchal RG, Mourich DV, Bradfute S, Hauck LL, Warfield KL, Iversen PL, Bavari S. Induced IL-10 Splice Altering Approach to Antiviral Drug Discovery. Nucleic Acid Ther. 2014;24(3):179-185. doi:10.1089/nat.2013.0457.

Unanchored K48-Linked Polyubiquitin Synthesized by the E3-Ubiquitin Ligase TRIM6 Stimulates the Interferon-IKKε Kinase-Mediated Antiviral Response

Authors:
Rajsbaum R, Versteeg GA, Schmid S, Maestre AM, Belicha-Villanueva A, Martínez-Romero C, Patel JR, Morrison J, Pisanelli G, Miorin L, Laurent-Rolle M, Moulton HM, Stein DA, Fernandez-Sesma A, tenOever BR, García-Sastre A
Citation:
Immunity. 2014;[Epub ahead of print] doi:10.1016/j.immuni.2014.04.018
Epub:
Yes
Abstract:
Type I interferons (IFN-I) are essential antiviral cytokines produced upon microbial infection. IFN-I elicits this activity...
Link:
http://www.sciencedirect.com/science/article/pii/S1074761314001800
Delivery Method:
peptide-linked
Organism or Cell Type:
BALB/c mice
Citation Extract:
Rajsbaum R, Versteeg GA, Schmid S, Maestre AM, Belicha-Villanueva A, Martínez-Romero C, Patel JR, Morrison J, Pisanelli G, Miorin L, Laurent-Rolle M, Moulton HM, Stein DA, Fernandez-Sesma A, tenOever BR, García-Sastre A. Unanchored K48-Linked Polyubiquitin Synthesized by the E3-Ubiquitin Ligase TRIM6 Stimulates the Interferon-IKKε Kinase-Mediated Antiviral Response. Immunity. 2014;[Epub ahead of print] doi:10.1016/j.immuni.2014.04.018.

Maternal thyroid hormones are essential for neural development in zebrafish

Authors:
Campinho MA, Saraiva J, Florindo C, Power DM
Citation:
Mol Endocrinol. 2014 May 30:me20141032. [Epub ahead of print]
Epub:
Yes
Abstract:
Teleost eggs contain an abundant store of maternal thyroid hormones (THs) and early in zebrafish embryonic development all the...
Link:
http://press.endocrine.org/doi/abs/10.1210/me.2014-1032
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Campinho MA, Saraiva J, Florindo C, Power DM. Maternal thyroid hormones are essential for neural development in zebrafish. Mol Endocrinol. 2014 May 30:me20141032. [Epub ahead of print].

Retinoic acid induced-1 (Rai1) regulates craniofacial and brain development in Xenopus

Authors:
Tahir R, Kennedy A, Elsea SH, Dickinson AJ
Citation:
Mech Dev. 2014 May 27. pii: S0925-4773(14)00028-8. doi: 10.1016/j.mod.2014.05.004. [Epub ahead of print]
Epub:
Yes
Abstract:
Retinoic acid induced-1 (RAI1) is an important yet understudied histone code reader that when mutated in humans results in...
Link:
http://www.sciencedirect.com/science/article/pii/S0925477314000288
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Tahir R, Kennedy A, Elsea SH, Dickinson AJ. Retinoic acid induced-1 (Rai1) regulates craniofacial and brain development in Xenopus. Mech Dev. 2014 May 27. pii: S0925-4773(14)00028-8. doi: 10.1016/j.mod.2014.05.004. [Epub ahead of print].

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