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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12455 scientific papers returned from the database with the search filters currently being used below.
There are 12455 scientific papers returned from the database with the search filters currently being used below.
Pharmacology of a central nervous system delivered 2'-o-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates
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Citation:
J Pharmacol Exp Ther. 2014 Jul;350(1):46-55. doi: 10.1124/jpet.113.212407. Epub 2014 Apr 30 Epub:
Not Epub Abstract:
Spinal muscular atrophy (SMA) is a debilitating neuromuscular disease caused by the loss of survival of motor neuron (SMN)... Delivery Method:
intracerebroventricular injection Organism or Cell Type:
mice Citation Extract: Rigo F, Chun SJ, Norris DA, Hung G, Lee S, Matson J, Fey RA, Gaus H, Hua Y, Grundy JS, Krainer AR, Henry SP, Bennett CF.. Pharmacology of a central nervous system delivered 2'-o-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates. J Pharmacol Exp Ther. 2014 Jul;350(1):46-55. doi: 10.1124/jpet.113.212407. Epub 2014 Apr 30. |
Ptena, but not Ptenb, reduces regeneration after spinal cord injury in adult zebrafish
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Citation:
Exp Neurol. 2014 Jun 11. pii: S0014-4886(14)00193-9. doi: 10.1016/j.expneurol.2014.06.006. [Epub ahead of print] Epub:
Yes Abstract:
Based on the observation that the tumor suppressor gene PTEN (phosphatase and tensin homolog) reduces regeneration after spinal... Organism or Cell Type:
zebrafish Citation Extract: Liu D, Yu Y, Schachner M. Ptena, but not Ptenb, reduces regeneration after spinal cord injury in adult zebrafish. Exp Neurol. 2014 Jun 11. pii: S0014-4886(14)00193-9. doi: 10.1016/j.expneurol.2014.06.006. [Epub ahead of print]. |
Ror2 Receptor Mediates Wnt11 Signaling and Affects Convergence and Extension Movements in Zebrafish
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Citation:
J Biol Chem. 2014 Jun 13. pii: jbc.M114.586099. [Epub ahead of print] Epub:
Not Epub Abstract:
The receptor tyrosine kinase Ror2 acts as an alternative receptor or coreceptor for Wnt5a and mediates Wnt5a-induced convergent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bai Y, Tan X, Zhang H, Liu C, Zhao B, Li Y, Lu L, Liu Y, Zhou J. Ror2 Receptor Mediates Wnt11 Signaling and Affects Convergence and Extension Movements in Zebrafish. J Biol Chem. 2014 Jun 13. pii: jbc.M114.586099. [Epub ahead of print]. |
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders
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Citation:
Nat Genet. 2013 Jun;45(6):621-31. doi: 10.1038/ng.2610. Epub 2013 Apr 14 Epub:
Not Epub Abstract:
Elevated resting heart rate is associated with greater risk of cardiovascular disease and mortality. In a 2-stage meta-analysis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, Boucher G, Cornelis MC, Gudbjartsson D, Hadley D, (authors deleted - database limit exceeded) Global BPgen Consortium; CARDIoGRAM Consortium, Erdmann J, Thompson JR; PR GWAS Consortium, Pfeufer A; QRS GWAS Consortium, Sotoodehnia N; QT-IGC Consortium, Newton-Cheh C; CHARGE-AF Consortium, Ellinor PT, Stricker BH, Metspalu A, Perola M, Beckmann JS, Smith GD, Stefansson K, Wareham NJ, Munroe PB, Sibon OC, Milan DJ, Snieder H, Samani NJ, Loos RJ. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet. 2013 Jun;45(6):621-31. doi: 10.1038/ng.2610. Epub 2013 Apr 14. |
Zebrafish ambra1a and ambra1b Knockdown Impairs Skeletal Muscle Development
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Citation:
PLoS One. 2014 Jun 12;9(6):e99210. doi: 10.1371/journal.pone.0099210. eCollection 2014 Epub:
Not Epub Abstract:
The essential role of autophagy in muscle homeostasis has been clearly demonstrated by phenotype analysis of mice with muscle-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Skobo T, Benato F, Grumati P, Meneghetti G, Cianfanelli V, Castagnaro S, Chrisam M, Di Bartolomeo S, Bonaldo P, Cecconi F, Valle LD. Zebrafish ambra1a and ambra1b Knockdown Impairs Skeletal Muscle Development. PLoS One. 2014 Jun 12;9(6):e99210. doi: 10.1371/journal.pone.0099210. eCollection 2014. |
Interferon-gamma directly mediates developmental biliary defects
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Citation:
Zebrafish. 2013 Jun;10(2):177-83. doi: 10.1089/zeb.2012.0815. Epub 2013 Feb 28 Epub:
Not Epub Abstract:
Biliary atresia (BA) is the most common identifiable hepatobiliary disease affecting infants, in which there are defects in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cui S, Eauclaire SF, Matthews RP. Interferon-gamma directly mediates developmental biliary defects. Zebrafish. 2013 Jun;10(2):177-83. doi: 10.1089/zeb.2012.0815. Epub 2013 Feb 28. |
Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo
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Citation:
J Cell Biol. 2013 Nov 25;203(4):673-89. doi: 10.1083/jcb.201304051. Epub 2013 Nov 18 Epub:
Not Epub Abstract:
Cell migration is essential for development, but its deregulation causes metastasis. The Scar/WAVE complex is absolutely... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Law AL, Vehlow A, Kotini M, Dodgson L, Soong D, Theveneau E, Bodo C, Taylor E, Navarro C, Perera U, Michael M, Dunn GA, Bennett D, Mayor R, Krause M. Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo. J Cell Biol. 2013 Nov 25;203(4):673-89. doi: 10.1083/jcb.201304051. Epub 2013 Nov 18. |
Atrophin-Rpd3 complex represses Hedgehog signaling by acting as a corepressor of CiR
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Citation:
J Cell Biol. 2013 Nov 25;203(4):575-83. doi: 10.1083/jcb.201306012 Epub:
Not Epub Abstract:
The evolutionarily conserved Hedgehog (Hh) signaling pathway is transduced by the Cubitus interruptus (Ci)/Gli family of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang Z, Feng J, Pan C, Lv X, Wu W, Zhou Z, Liu F, Zhang L, Zhao Y. Atrophin-Rpd3 complex represses Hedgehog signaling by acting as a corepressor of CiR. J Cell Biol. 2013 Nov 25;203(4):575-83. doi: 10.1083/jcb.201306012. |
Local caspase activation interacts with Slit-Robo signaling to restrict axonal arborization
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Citation:
J Cell Biol. 2013 Nov 25;203(4):657-72. doi: 10.1083/jcb.201303072 Epub:
Not Epub Abstract:
In addition to being critical for apoptosis, components of the apoptotic pathway, such as caspases, are involved in other... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Campbell DS, Okamoto H. Local caspase activation interacts with Slit-Robo signaling to restrict axonal arborization. J Cell Biol. 2013 Nov 25;203(4):657-72. doi: 10.1083/jcb.201303072. |
Reverse engineering validation using a benchmark synthetic gene circuit in human cells
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Citation:
ACS Synth Biol. 2013 May 17;2(5):255-62. doi: 10.1021/sb300093y. Epub 2013 Mar 28 Epub:
Not Epub Abstract:
Multicomponent biological networks are often understood incompletely, in large part due to the lack of reliable and robust... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HEK293 Citation Extract: Kang T, White JT, Xie Z, Benenson Y, Sontag E, Bleris L. Reverse engineering validation using a benchmark synthetic gene circuit in human cells. ACS Synth Biol. 2013 May 17;2(5):255-62. doi: 10.1021/sb300093y. Epub 2013 Mar 28. |