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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators
Citation:
J Clin Invest. 2014;[Epub ahead of print] doi:10.1172/JCI71898 Epub:
Not Epub Abstract:
Cilia are critical mediators of paracrine signaling; however, it is unknown whether proteins that contribute to ciliopathies... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu YP, Tsai I-C, Morleo M, Oh EC, Leitch CC, Massa F, Lee B-H, Parker DS, Finley D, Zaghloul NA, Franco B, Katsanis NK. Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators. J Clin Invest. 2014;[Epub ahead of print] doi:10.1172/JCI71898. |
Functional analysis of candidate genes in 2q13 deletion syndrome implicates FBLN7 and TMEM87B deficiency in congenital heart defects and FBLN7 in craniofacial malformations
Citation:
Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu144 Epub:
Yes Abstract:
Recurrent 2q13 deletion syndrome is associated with incompletely penetrant severe cardiac defects and craniofacial anomalies.... Organism or Cell Type:
zebrafish Citation Extract: Russell MR, Raeker MO, Geisler SB, Thomas PE, Simmons TA, Bernat JA, Thorsson T, Innis JW. Functional analysis of candidate genes in 2q13 deletion syndrome implicates FBLN7 and TMEM87B deficiency in congenital heart defects and FBLN7 in craniofacial malformations. Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu144. |
A novel serotonin-secreting cell type regulates ciliary motility in the mucociliary epidermis of Xenopus tadpoles
Citation:
Development. 2014 Apr;141(7):1526-33. doi: 10.1242/dev.102343. Epub 2014 Mar 5 Epub:
Not Epub Abstract:
The embryonic skin of Xenopus tadpoles serves as an experimental model system for mucociliary epithelia (MCE) such as the human... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Walentek P, Bogusch S, Thumberger T, Vick P, Dubaissi E, Beyer T, Blum M, Schweickert A. A novel serotonin-secreting cell type regulates ciliary motility in the mucociliary epidermis of Xenopus tadpoles. Development. 2014 Apr;141(7):1526-33. doi: 10.1242/dev.102343. Epub 2014 Mar 5. |
Heparanase 2, mutated in urofacial syndrome, mediates peripheral neural development in Xenopus
Citation:
Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu147 Epub:
Yes Abstract:
Urofacial syndrome (UFS; previously Ochoa syndrome) is an autosomal recessive disease characterised by incomplete bladder... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Roberts NA, Woolf AS, Stuart HM, Thuret R, McKenzie EA, Newman WG, Hilton EN. Heparanase 2, mutated in urofacial syndrome, mediates peripheral neural development in Xenopus. Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu147. |
Antisense Oligonucleotide-Based Therapy in Human Erythropoietic Protoporphyria
Citation:
Am J Hum Genet. 2014 Mar 26. pii: S0002-9297(14)00068-8. doi: 10.1016/j.ajhg.2014.02.010. [Epub ahead of print] Epub:
Not Epub Abstract:
In 90% of people with erythropoietic protoporphyria (EPP), the disease results from the inheritance of a common hypomorphic... Organism or Cell Type:
cell culture Citation Extract: Oustric V, Manceau H, Ducamp S, Soaid R, Karim Z, Schmitt C, Mirmiran A, Peoc'h K, Grandchamp B, Beaumont C, Lyoumi S, Moreau-Gaudry F, Guyonnet-Dupérat V, de Verneuil H, Marie J, Puy H, Deybach JC, Gouya L. Antisense Oligonucleotide-Based Therapy in Human Erythropoietic Protoporphyria. Am J Hum Genet. 2014 Mar 26. pii: S0002-9297(14)00068-8. doi: 10.1016/j.ajhg.2014.02.010. [Epub ahead of print]. |
IRE1α is essential for Xenopus pancreas development
Citation:
J Biomed Res. 2014 Mar;28(2):123-31. doi: 10.7555/JBR.28.20130076. Epub 2013 Dec 25 Epub:
Not Epub Abstract:
Inositol requiring enzyme-1 (IRE1) is highly conserved from yeasts to humans. Upon the endoplasmic reticulum (ER) stress, IRE1... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Yuan L, Li X, Feng J, Yin C, Yuan F, Wang X. IRE1α is essential for Xenopus pancreas development. J Biomed Res. 2014 Mar;28(2):123-31. doi: 10.7555/JBR.28.20130076. Epub 2013 Dec 25. |
3' end formation of pre-mRNA and phosphorylation of Ser2 on the RNA polymerase II CTD are reciprocally coupled in human cells
Citation:
Genes Dev. 2014 Feb 15;28(4):342-56. doi: 10.1101/gad.231274.113. Epub 2014 Jan 29 Epub:
Yes Abstract:
3' end formation of pre-mRNAs is coupled to their transcription via the C-terminal domain (CTD) of RNA polymerase II (Pol... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HEK293 Citation Extract: Davidson L, Muniz L, West S. 3' end formation of pre-mRNA and phosphorylation of Ser2 on the RNA polymerase II CTD are reciprocally coupled in human cells. Genes Dev. 2014 Feb 15;28(4):342-56. doi: 10.1101/gad.231274.113. Epub 2014 Jan 29. |
Angiopoietin-like 3 regulates hepatocyte proliferation and lipid metabolism in zebrafish
Citation:
Biochem Biophys Res Comm. 2014;[Epub ahead of print] doi:10.1016/j.bbrc.2014.03.099 Epub:
Yes Abstract:
Loss-of-function mutations in angiopoietin-like 3 (ANGPTL3) cause familial hypobetalipoproteinemia type 2 (FHBL2) in humans.... Organism or Cell Type:
zebrafish Citation Extract: Lee S-H, So J-H, Kim H-T, Choi J-W, Lee M-S, Choi S-Y, Kim C-H, Kim MJ. Angiopoietin-like 3 regulates hepatocyte proliferation and lipid metabolism in zebrafish. Biochem Biophys Res Comm. 2014;[Epub ahead of print] doi:10.1016/j.bbrc.2014.03.099. |
A Zebrafish Chemical Suppressor Screening Identifies Small Molecule Inhibitors of the Wnt/β-catenin Pathway
Citation:
Chem & Biol. 2014;[Epub ahead of print] doi:10.1016/j.chembiol.2014.02.015 Epub:
Not Epub Abstract:
Genetic screening for suppressor mutants has been successfully used to identify important signaling regulators. Using an... Organism or Cell Type:
zebrafish Citation Extract: Nishiya N, Oku Y, Kumagai Y, Sato Y, Yamaguchi E, Sasaki A, Shoji M, Ohnishi Y, Okamoto H, Uehara Y. A Zebrafish Chemical Suppressor Screening Identifies Small Molecule Inhibitors of the Wnt/β-catenin Pathway. Chem & Biol. 2014;[Epub ahead of print] doi:10.1016/j.chembiol.2014.02.015. |
SLC7A14 linked to autosomal recessive retinitis pigmentosa
Citation:
Nat Commun. 2014 Mar 27;5:3517. doi: 10.1038/ncomms4517 Epub:
Not Epub Abstract:
Retinitis pigmentosa (RP) is characterized by degeneration of the retinal photoreceptors and is the leading cause of inherited... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jin ZB, Huang XF, Lv JN, Xiang L, Li DQ, Chen J, Huang C, Wu J, Lu F, Qu J. SLC7A14 linked to autosomal recessive retinitis pigmentosa. Nat Commun. 2014 Mar 27;5:3517. doi: 10.1038/ncomms4517. |