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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

The endoderm gene regulatory network in sea urchin embryos up to mid-blastula stage

Authors:
Peter IS, Davidson EH
Citation:
Dev Biol. 2010 Apr 15;340(2):188-99. doi: 10.1016/j.ydbio.2009.10.037. Epub 2009 Nov 3
Epub:
Not Epub
Abstract:
As the result of early specification processes, sea urchin embryos eventually form various mesodermal cell lineages and a gut...
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Peter IS, Davidson EH. The endoderm gene regulatory network in sea urchin embryos up to mid-blastula stage. Dev Biol. 2010 Apr 15;340(2):188-99. doi: 10.1016/j.ydbio.2009.10.037. Epub 2009 Nov 3.

CHD7, the gene mutated in CHARGE syndrome, regulates genes involved in neural crest cell guidance

Authors:
Schulz Y, Wehner P, Opitz L, Salinas-Riester G, Bongers EMHF, van Ravenswaaij-Arts CMA, Wincent J, Schoumans J, Kohlhase J, Borchers A, Pauli S
Citation:
Hum Genet. 2014;[Epub ahead of print] doi:10.1007/s00439-014-1444-2
Epub:
Yes
Abstract:
Heterozygous loss of function mutations in CHD7 (chromodomain helicase DNA-binding protein 7) lead to CHARGE syndrome, a...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Schulz Y, Wehner P, Opitz L, Salinas-Riester G, Bongers EMHF, van Ravenswaaij-Arts CMA, Wincent J, Schoumans J, Kohlhase J, Borchers A, Pauli S. CHD7, the gene mutated in CHARGE syndrome, regulates genes involved in neural crest cell guidance. Hum Genet. 2014;[Epub ahead of print] doi:10.1007/s00439-014-1444-2.

Spinal Muscular Atrophy Phenotype Is Ameliorated Either By SMN Increase Or Modulation Of Secondary Cell Death Events With RNA Therapy (S56.006)

Authors:
Riboldi G, Nizzardo M, Simone C, Rizzo F, Ruggieri M, Pagliarani S, Ulzi G, Salani S, DalMas A, Bucchia M, Frattini E, Stuppia G, Magri F, Bresolin N, Pagani F, Comi G, Corti S
Citation:
Neurology. 2014;82(10):Supplement S56.006
Epub:
Not Epub
Abstract:
OBJECTIVE: The aim of the study was to develop therapeutic strategies based on RNA modulation for Spinal Muscular Atrophy (SMA...
Organism or Cell Type:
cell culture: SMA motor neurons
Citation Extract:
Riboldi G, Nizzardo M, Simone C, Rizzo F, Ruggieri M, Pagliarani S, Ulzi G, Salani S, DalMas A, Bucchia M, Frattini E, Stuppia G, Magri F, Bresolin N, Pagani F, Comi G, Corti S. Spinal Muscular Atrophy Phenotype Is Ameliorated Either By SMN Increase Or Modulation Of Secondary Cell Death Events With RNA Therapy (S56.006). Neurology. 2014;82(10):Supplement S56.006 .

TIGAR Inhibition Rescues Dopaminergic Neurons in Common Forms of Early Onset Parkinson's' Disease (I5-2.003)

Authors:
Bandmann O, Keatinge M, DaCosta M, Mortiboys H, Flinn L
Citation:
Neurology. 2014;82(10):Supplement I5-2.003
Epub:
Not Epub
Abstract:
OBJECTIVE: To identify novel mechanisms which lead to dopaminergic cell death in early onset PD (EOPD) and determine whether...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bandmann O, Keatinge M, DaCosta M, Mortiboys H, Flinn L. TIGAR Inhibition Rescues Dopaminergic Neurons in Common Forms of Early Onset Parkinson's' Disease (I5-2.003). Neurology. 2014;82(10):Supplement I5-2.003.

Isradipine Rescues Alpha-synuclein Toxicity in a ZebrafishModel of Parkinson’s Disease by Upregulating Autophagy (1II-2.004)

Authors:
Stahl M, Prabhudesai S, Lulla A, Bronstein J
Citation:
Neurology. 2014. 82(10):Supplement 1II-2.004
Epub:
Not Epub
Abstract:
OBJECTIVE: To investigate the effect of isradipine, an L-type calcium channel blocker of the dihydropyridine class, on a...
Organism or Cell Type:
zebrafish
Citation Extract:
Stahl M, Prabhudesai S, Lulla A, Bronstein J. Isradipine Rescues Alpha-synuclein Toxicity in a ZebrafishModel of Parkinson’s Disease by Upregulating Autophagy (1II-2.004). Neurology. 2014. 82(10):Supplement 1II-2.004.

Protein tyrosine phosphatase PTPN9 regulates erythroid cell development through STAT3 dephosphorylation in zebrafish

Authors:
Bu Y, Su F, Wang X, Gao H, Lei L, Chang N, Wu Q, Hu K, Zhu X, Chang Z, Meng K, Xiong J-W
Citation:
J Cell Sci. 2014 Jun 15;127(Pt 12):2761-70. doi: 10.1242/jcs.145367. Epub 2014 Apr 11
Epub:
Yes
Abstract:
Protein tyrosine phosphatases (PTPs) such as SHP-1, SHP-2 and CD45 are involved in hematopoiesis, but the function of many PTPs...
Organism or Cell Type:
zebrafish
Citation Extract:
Bu Y, Su F, Wang X, Gao H, Lei L, Chang N, Wu Q, Hu K, Zhu X, Chang Z, Meng K, Xiong J-W. Protein tyrosine phosphatase PTPN9 regulates erythroid cell development through STAT3 dephosphorylation in zebrafish. J Cell Sci. 2014 Jun 15;127(Pt 12):2761-70. doi: 10.1242/jcs.145367. Epub 2014 Apr 11.

Antisense-Mediated Therapeutic Pseudoexon Skipping In Tmem165-Cdg

Authors:
Yuste-Checa P, Medrano C, Gámez A, Desviat L, Matthijs G, Ugarte M, Pérez-Cerdá C, Pérez B
Citation:
Clin Genet. 2014 Apr 10. doi: 10.1111/cge.12402. [Epub ahead of print]
Epub:
Yes
Abstract:
Deficiencies in glycosyltransferases, glycosidases or nucleotide-sugar transporters involved in protein glycosylation lead to...
Organism or Cell Type:
cell culture: patient-derived fibroblasts
Citation Extract:
Yuste-Checa P, Medrano C, Gámez A, Desviat L, Matthijs G, Ugarte M, Pérez-Cerdá C, Pérez B. Antisense-Mediated Therapeutic Pseudoexon Skipping In Tmem165-Cdg. Clin Genet. 2014 Apr 10. doi: 10.1111/cge.12402. [Epub ahead of print].

Sp8 regulates inner ear development

Authors:
Chung HA, Medina-Ruiz S, Harland RM
Citation:
PNAS. 2014;[Epub ahead of print] doi:10.1073/pnas.1319301111
Epub:
Not Epub
Abstract:
Deficits in hearing or balance are common and result from both developmental and environmental causes. Model organisms have...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Chung HA, Medina-Ruiz S, Harland RM. Sp8 regulates inner ear development. PNAS. 2014;[Epub ahead of print] doi:10.1073/pnas.1319301111 .

A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development

Authors:
Villefranc JA, Nicoli S, Bentley K, Jeltsch M, Zarkada G, Moore JC, Gerhardt H, Alitalo K, Lawson ND
Citation:
Development. 2013 Apr;140(7):1497-506. doi:10.1242/dev.084152. Epub 2013 Mar 5
Epub:
Not Epub
Abstract:
Vascular endothelial growth factor C (Vegfc) is a secreted protein that guides lymphatic development in vertebrate embryos....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Villefranc JA, Nicoli S, Bentley K, Jeltsch M, Zarkada G, Moore JC, Gerhardt H, Alitalo K, Lawson ND. A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development. Development. 2013 Apr;140(7):1497-506. doi:10.1242/dev.084152. Epub 2013 Mar 5.

Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut

Authors:
Dush MK, Nascone-Yoder NM
Citation:
Development. 2013 Apr;140(7):1457-66. doi: 10.1242/dev.086850. Epub 2013 Mar 5
Epub:
Not Epub
Abstract:
Tissue elongation is a fundamental morphogenetic process that generates the proper anatomical topology of the body plan and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Dush MK, Nascone-Yoder NM. Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut. Development. 2013 Apr;140(7):1457-66. doi: 10.1242/dev.086850. Epub 2013 Mar 5.

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