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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Formation and cultivation of medaka primordial germ cells

Authors:
Li Z, Li M, Hong N, Yi M, Hong Y
Citation:
Cell Tiss Res. 2014:{Epub ahead pf print} doi:10.1007/s00441-014-1867-z
Epub:
Yes
Abstract:
Primordial germ cell (PGC) formation is pivotal for fertility. Mammalian PGCs are epigenetically induced without the need for...
Delivery Method:
microinjection
Organism or Cell Type:
Medaka (Oryzias latipes)
Citation Extract:
Li Z, Li M, Hong N, Yi M, Hong Y. Formation and cultivation of medaka primordial germ cells. Cell Tiss Res. 2014:{Epub ahead pf print} doi:10.1007/s00441-014-1867-z.

Identification of KLHL41 Mutations Implicates BTB-Kelch-Mediated Ubiquitination as an Alternate Pathway to Myofibrillar Disruption in Nemaline Myopathy

Authors:
Gupta VA, Ravenscroft G, Shaheen R, Todd EJ, Swanson LC, Shiina M, Ogata K, Hsu C, Clarke NF, Darras BT, Farrar MA, Hashem A, Manton ND, Muntoni F, North KN, Sandaradura SA, Nishino I, Hayashi YK, Sewry CA, Thompson EM, Yau KS, Brownstein CA, Yu TW, Allcock RJ, Davis MR, Wallgren-Pettersson C, Matsumoto N, Alkuraya FS, Laing NG, Beggs AH
Citation:
Am J Hum Genet. 2013 Dec 5;93(6):1108-17. doi: 10.1016/j.ajhg.2013.10.020. Epub 2013 Nov 21
Epub:
Not Epub
Abstract:
Nemaline myopathy (NM) is a rare congenital muscle disorder primarily affecting skeletal muscles that results in neonatal death...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gupta VA, Ravenscroft G, Shaheen R, Todd EJ, Swanson LC, Shiina M, Ogata K, Hsu C, Clarke NF, Darras BT, Farrar MA, Hashem A, Manton ND, Muntoni F, North KN, Sandaradura SA, Nishino I, Hayashi YK, Sewry CA, Thompson EM, Yau KS, Brownstein CA, Yu TW, Allcock RJ, Davis MR, Wallgren-Pettersson C, Matsumoto N, Alkuraya FS, Laing NG, Beggs AH. Identification of KLHL41 Mutations Implicates BTB-Kelch-Mediated Ubiquitination as an Alternate Pathway to Myofibrillar Disruption in Nemaline Myopathy. Am J Hum Genet. 2013 Dec 5;93(6):1108-17. doi: 10.1016/j.ajhg.2013.10.020. Epub 2013 Nov 21.

CLP1 Founder Mutation Links tRNA Splicing and Maturation to Cerebellar Development and Neurodegeneration

Authors:
Schaffer AE, Eggens VRC, Caglayan AO, Reuter MS, Scott E, Coufal NG, Silhavy JL, Xue Y, Kayserili H, Yasuno K, Rosti RO, Abdellateef M, Caglar C, Kasher PR, Cazemier JL, Weterman MA, Cantagrel V, Cai N, Zweier C, Altunoglu U, Satkin NB, Aktar F, Tuysuz B, Yalcinkaya C, Caksen H, Bilguvar K, Fu X-D, Trotta CR, Gabriel S, Reis A, Gunel M, Baas F, Gleeson JG
Citation:
Cell. 2014;157(3):651-63. doi:10.1016/j.cell.2014.03.049
Epub:
Not Epub
Abstract:
Neurodegenerative diseases can occur so early as to affect neurodevelopment. From a cohort of more than 2,000 consanguineous...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schaffer AE, Eggens VRC, Caglayan AO, Reuter MS, Scott E, Coufal NG, Silhavy JL, Xue Y, Kayserili H, Yasuno K, Rosti RO, Abdellateef M, Caglar C, Kasher PR, Cazemier JL, Weterman MA, Cantagrel V, Cai N, Zweier C, Altunoglu U, Satkin NB, Aktar F, Tuysuz B, Yalcinkaya C, Caksen H, Bilguvar K, Fu X-D, Trotta CR, Gabriel S, Reis A, Gunel M, Baas F, Gleeson JG. CLP1 Founder Mutation Links tRNA Splicing and Maturation to Cerebellar Development and Neurodegeneration. Cell. 2014;157(3):651-63. doi:10.1016/j.cell.2014.03.049.

A conserved axon type hierarchy governing peripheral nerve assembly

Authors:
Wang L, Mongera A, Bonanomi D, Cyganek L, Pfaff SL, Nüsslein-Volhard C, Marquardt T
Citation:
Development. 2014 May;141(9):1875-83. doi: 10.1242/dev.106211. Epub 2014 Apr 3
Epub:
Not Epub
Abstract:
In gnathostome vertebrates, including fish, birds and mammals, peripheral nerves link nervous system, body and immediate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang L, Mongera A, Bonanomi D, Cyganek L, Pfaff SL, Nüsslein-Volhard C, Marquardt T. A conserved axon type hierarchy governing peripheral nerve assembly. Development. 2014 May;141(9):1875-83. doi: 10.1242/dev.106211. Epub 2014 Apr 3.

Pkd1 Regulates Lymphatic Vascular Morphogenesis during Development

Authors:
Coxam B, Sabine A, Bower NI, Smith KA, Pichol-Thievend C, Skoczylas R, Astin JW, Frampton E, Jaquet M, Crosier PS, Parton RG, Harvey NL, Petrova TV, Schulte-Merker S, Francois M, Hogan BM
Citation:
Cell Rep. 2014; doi:10.1016/j.celrep.2014.03.063
Epub:
Yes
Abstract:
Lymphatic vessels arise during development through sprouting of precursor cells from veins, which is regulated by known...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Coxam B, Sabine A, Bower NI, Smith KA, Pichol-Thievend C, Skoczylas R, Astin JW, Frampton E, Jaquet M, Crosier PS, Parton RG, Harvey NL, Petrova TV, Schulte-Merker S, Francois M, Hogan BM. Pkd1 Regulates Lymphatic Vascular Morphogenesis during Development. Cell Rep. 2014; doi:10.1016/j.celrep.2014.03.063.

WLS Retrograde Transport to the Endoplasmic Reticulum during Wnt Secretion

Authors:
Yu J, Chia J, Canning CA, Jones CM, Bard FA, Virshup DM
Citation:
Dev Cell. 2014:[Epub ahead of print] doi:10.1016/j.devcel.2014.03.016
Epub:
Yes
Abstract:
Wnts are transported to the cell surface by the integral membrane protein WLS (also known as Wntless, Evi, and GPR177)....
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yu J, Chia J, Canning CA, Jones CM, Bard FA, Virshup DM. WLS Retrograde Transport to the Endoplasmic Reticulum during Wnt Secretion. Dev Cell. 2014:[Epub ahead of print] doi:10.1016/j.devcel.2014.03.016.

Essential roles of zebrafish rtn4/Nogo paralogues in embryonic development

Authors:
Pinzón-Olejua A, Welte C, Abdesselem H, Málaga-Trillo E, Stuermer CA
Citation:
Neural Dev. 2014 Apr 23;9(1):8. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: As a consequence of gene/genome duplication, the RTN4/Nogo gene has two counterparts in zebrafish: rtn4a and rtn4b...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pinzón-Olejua A, Welte C, Abdesselem H, Málaga-Trillo E, Stuermer CA. Essential roles of zebrafish rtn4/Nogo paralogues in embryonic development. Neural Dev. 2014 Apr 23;9(1):8. [Epub ahead of print].

Fluoxetine prevents dystrophic changes in a zebrafish model of Duchenne muscular dystrophy

Authors:
Waugh TA, Horstick E, Hur J, Jackson SW, Davidson AE, Li X, Dowling JJ
Citation:
Hum Mol Genet. 2014 Apr 23. [Epub ahead of print]
Epub:
Yes
Abstract:
Duchenne muscular dystrophy (DMD) is a common and relentlessly progressive muscle disease. Some interventions have been...
Organism or Cell Type:
zebrafish
Citation Extract:
Waugh TA, Horstick E, Hur J, Jackson SW, Davidson AE, Li X, Dowling JJ. Fluoxetine prevents dystrophic changes in a zebrafish model of Duchenne muscular dystrophy. Hum Mol Genet. 2014 Apr 23. [Epub ahead of print].

Frizzled 5 signaling governs the neural potential of progenitors in the developing Xenopus retina

Authors:
Van Raay TJ, Moore KB, Iordanova I, Steele M, Jamrich M, Harris WA, Vetter ML
Citation:
Neuron. 2005 Apr 7;46(1):23-36
Epub:
Not Epub
Abstract:
Progenitors in the developing central nervous system acquire neural potential and proliferate to expand the pool of precursors...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Van Raay TJ, Moore KB, Iordanova I, Steele M, Jamrich M, Harris WA, Vetter ML. Frizzled 5 signaling governs the neural potential of progenitors in the developing Xenopus retina. Neuron. 2005 Apr 7;46(1):23-36.

High-resolution analysis of gene activity during the Xenopus mid-blastula transition

Authors:
Collart C, Owens ND, Bhaw-Rosun L, Cooper B, De Domenico E, Patrushev I, Sesay AK, Smith JN, Smith JC, Gilchrist MJ
Citation:
Development. 2014 May;141(9):1927-39. doi: 10.1242/dev.102012
Epub:
Not Epub
Abstract:
The Xenopus mid-blastula transition (MBT) marks the onset of large-scale zygotic transcription, as well as an increase in cell...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Collart C, Owens ND, Bhaw-Rosun L, Cooper B, De Domenico E, Patrushev I, Sesay AK, Smith JN, Smith JC, Gilchrist MJ. High-resolution analysis of gene activity during the Xenopus mid-blastula transition. Development. 2014 May;141(9):1927-39. doi: 10.1242/dev.102012.

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