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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Homeodomain protein otp and activity-dependent splicing modulate neuronal adaptation to stress

Authors:
Amir-Zilberstein L, Blechman J, Sztainberg Y, Norton WH, Reuveny A, Borodovsky N, Tahor M, Bonkowsky JL, Bally-Cuif L, Chen A, Levkowitz G
Citation:
Neuron. 2012 Jan 26;73(2):279-91. doi: 10.1016/j.neuron.2011.11.019
Epub:
Not Epub
Abstract:
Regulation of corticotropin-releasing hormone (CRH) activity is critical for the animal's adaptation to stressful...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Amir-Zilberstein L, Blechman J, Sztainberg Y, Norton WH, Reuveny A, Borodovsky N, Tahor M, Bonkowsky JL, Bally-Cuif L, Chen A, Levkowitz G. Homeodomain protein otp and activity-dependent splicing modulate neuronal adaptation to stress. Neuron. 2012 Jan 26;73(2):279-91. doi: 10.1016/j.neuron.2011.11.019.

Eph/Ephrin signaling regulates the mesenchymal-to-epithelial transition of the paraxial mesoderm during somite morphogenesis

Authors:
Barrios A, Poole RJ, Durbin L, Brennan C, Holder N, Wilson SW
Citation:
Curr Biol. 2003 Sep 16;13(18):1571-82
Epub:
Not Epub
Abstract:
BACKGROUND: During somitogenesis, segmental patterns of gene activity provide the instructions by which mesenchymal cells...
Delivery Method:
microinjection
Citation Extract:
Barrios A, Poole RJ, Durbin L, Brennan C, Holder N, Wilson SW. Eph/Ephrin signaling regulates the mesenchymal-to-epithelial transition of the paraxial mesoderm during somite morphogenesis. Curr Biol. 2003 Sep 16;13(18):1571-82.

Manipulation of BK channel expression is sufficient to alter auditory hair cell thresholds in larval zebrafish

Authors:
Rohmann KN, Tripp JA, Genova RM, Bass AH
Citation:
J Exp Biol. 2014;[Epub ahead of print] doi:10.1242/jeb.103093
Epub:
Yes
Abstract:
Non-mammalian vertebrates rely on electrical resonance for frequency tuning in auditory hair cells. A key component of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rohmann KN, Tripp JA, Genova RM, Bass AH. Manipulation of BK channel expression is sufficient to alter auditory hair cell thresholds in larval zebrafish. J Exp Biol. 2014;[Epub ahead of print] doi:10.1242/jeb.103093.

Genome-wide studies of copy number variation and exome sequencing identify rare variants in BAG3 as a cause of dilated cardiomyopathy

Authors:
Norton N, Li D, Rieder MJ, Siegfried JD, Rampersaud E, Züchner S, Mangos S, Gonzalez-Quintana J, Wang L, McGee S, Reiser J, Martin E, Nickerson DA, Hershberger RE
Citation:
Am J Hum Genet. 2011 Mar 11;88(3):273-82. doi: 10.1016/j.ajhg.2011.01.016. Epub 2011 Feb 25
Epub:
Not Epub
Abstract:
Dilated cardiomyopathy commonly causes heart failure and is the most frequent precipitating cause of heart transplantation....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Norton N, Li D, Rieder MJ, Siegfried JD, Rampersaud E, Züchner S, Mangos S, Gonzalez-Quintana J, Wang L, McGee S, Reiser J, Martin E, Nickerson DA, Hershberger RE. Genome-wide studies of copy number variation and exome sequencing identify rare variants in BAG3 as a cause of dilated cardiomyopathy. Am J Hum Genet. 2011 Mar 11;88(3):273-82. doi: 10.1016/j.ajhg.2011.01.016. Epub 2011 Feb 25.

Expression of zebrafish anterior gradient 2 in the semicircular canals and supporting cells of otic vesicle sensory patches is regulated by Sox10

Authors:
Tang CH, Lai YR, Chen YC, Li CH, Lu YF, Chen HY, Lien HW, Yang CH, Huang CJ, Wang CY, Kao CF, Hwang SP
Citation:
Biochim Biophys Acta. 2014 Apr 21. pii: S1874-9399(14)00094-7. doi: 10.1016/j.bbagrm.2014.04.017. [Epub ahead of print]
Epub:
Not Epub
Abstract:
AGR2 is a member of the protein disulfide isomerase (PDI) family, which is implicated in cancer cell growth and metastasis,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tang CH, Lai YR, Chen YC, Li CH, Lu YF, Chen HY, Lien HW, Yang CH, Huang CJ, Wang CY, Kao CF, Hwang SP. Expression of zebrafish anterior gradient 2 in the semicircular canals and supporting cells of otic vesicle sensory patches is regulated by Sox10. Biochim Biophys Acta. 2014 Apr 21. pii: S1874-9399(14)00094-7. doi: 10.1016/j.bbagrm.2014.04.017. [Epub ahead of print].

Involvement of histamine in endothelium-dependent relaxation of mesenteric lymphatic vessels

Authors:
Nizamutdinova IT, Maejima D, Nagai T, Bridenbaugh E, Thangaswamy S, Chatterjee V, Meininger CJ, Gashev AA
Citation:
Microcirculation. 2014 Apr 21. doi: 10.1111/micc.12143. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVES: The knowledge of the basic principles of lymphatic function, still remains, to a large degree, rudimentary and will...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
rat
Citation Extract:
Nizamutdinova IT, Maejima D, Nagai T, Bridenbaugh E, Thangaswamy S, Chatterjee V, Meininger CJ, Gashev AA. Involvement of histamine in endothelium-dependent relaxation of mesenteric lymphatic vessels. Microcirculation. 2014 Apr 21. doi: 10.1111/micc.12143. [Epub ahead of print].

Microenvironmental Regulation of Telomerase Isoforms in Human Embryonic Stem Cells

Authors:
Radan L, Hughes CS, Teichroeb JH, Vieira Zamora FM, Jewer M, Postovit LM, Betts DH
Citation:
Stem Cells Dev. 2014 Apr 22. [Epub ahead of print]
Epub:
Yes
Abstract:
Recent evidence points to extra-telomeric, non-canonical roles for telomerase in regulating stem cell function. In this study,...
Organism or Cell Type:
cell culture: human embryonic stem cells (hESCs)
Citation Extract:
Radan L, Hughes CS, Teichroeb JH, Vieira Zamora FM, Jewer M, Postovit LM, Betts DH. Microenvironmental Regulation of Telomerase Isoforms in Human Embryonic Stem Cells. Stem Cells Dev. 2014 Apr 22. [Epub ahead of print].

Knocking down 10-formyltetrahydrofolate dehydrogenase increased oxidative stress and impeded zebrafish embryogenesis by obstructing morphogenetic movement

Authors:
Chang WN, Lee GH, Kao TT, Lin CY, Hsiao TH, Tsai JN, Chen BH, Chen YH, Wu HR, Tsai HJ, Fu TF
Citation:
Biochim Biophys Acta. 2014 Apr 18. pii: S0304-4165(14)00142-1. doi: 10.1016/j.bbagen.2014.04.009. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Folate is an essential nutrient for cell survival and embryogenesis. 10-Formyltetrahydrofolate dehydrogenase (FDH)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chang WN, Lee GH, Kao TT, Lin CY, Hsiao TH, Tsai JN, Chen BH, Chen YH, Wu HR, Tsai HJ, Fu TF. Knocking down 10-formyltetrahydrofolate dehydrogenase increased oxidative stress and impeded zebrafish embryogenesis by obstructing morphogenetic movement. Biochim Biophys Acta. 2014 Apr 18. pii: S0304-4165(14)00142-1. doi: 10.1016/j.bbagen.2014.04.009. [Epub ahead of print].

Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia

Authors:
Wallmeier J, Al-Mutairi DA, Chen CT, Loges NT, Pennekamp P, Menchen T, Ma L, Shamseldin HE, Olbrich H, Dougherty GW, Werner C, Alsabah BH, Köhler G, Jaspers M, Boon M, Griese M, Schmitt-Grohé S, Zimmermann T, Koerner-Rettberg C, Horak E, Kintner C, Alkuraya FS, Omran H
Citation:
Nat Genet. 2014 Apr 20. doi: 10.1038/ng.2961. [Epub ahead of print]
Epub:
Yes
Abstract:
Using a whole-exome sequencing strategy, we identified recessive CCNO (encoding cyclin O) mutations in 16 individuals suffering...
Organism or Cell Type:
Xenopus
Citation Extract:
Wallmeier J, Al-Mutairi DA, Chen CT, Loges NT, Pennekamp P, Menchen T, Ma L, Shamseldin HE, Olbrich H, Dougherty GW, Werner C, Alsabah BH, Köhler G, Jaspers M, Boon M, Griese M, Schmitt-Grohé S, Zimmermann T, Koerner-Rettberg C, Horak E, Kintner C, Alkuraya FS, Omran H. Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia. Nat Genet. 2014 Apr 20. doi: 10.1038/ng.2961. [Epub ahead of print].

Identification of a splicing variant that regulates type 2 diabetes risk factor CDKAL1 level by a coding-independent mechanism in human

Authors:
Zhou B, Wei FY, Kanai N, Fujimura A, Kaitsuka T, Tomizawa K
Citation:
Hum Mol Genet. 2014 Apr 23. [Epub ahead of print]
Epub:
Yes
Abstract:
SNPs in CDKAL1 have been associated with the development of type 2 diabetes (T2D). CDKAL1 catalyzes 2-methylthio modification...
Citation Extract:
Zhou B, Wei FY, Kanai N, Fujimura A, Kaitsuka T, Tomizawa K. Identification of a splicing variant that regulates type 2 diabetes risk factor CDKAL1 level by a coding-independent mechanism in human. Hum Mol Genet. 2014 Apr 23. [Epub ahead of print].

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