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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Inhibition of enterovirus 71 infection by antisense octaguanidinium dendrimer-conjugated morpholino oligomers

Authors:
Tan CW, Chan YF, Quah YW, Poh CL
Citation:
Antiviral Res. 2014 Jul;107:35-41. doi: 10.1016/j.antiviral.2014.04.004. Epub 2014 Apr 24. PMID: 24769243; PMCID: PMC7118997
Epub:
Yes
Abstract:
Enterovirus 71 (EV-71) infections are generally manifested as mild hand, foot and mouth disease, but have been reported to...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: RD cells
Citation Extract:
Tan CW, Chan YF, Quah YW, Poh CL. Inhibition of enterovirus 71 infection by antisense octaguanidinium dendrimer-conjugated morpholino oligomers. Antiviral Res. 2014 Jul;107:35-41. doi: 10.1016/j.antiviral.2014.04.004. Epub 2014 Apr 24. PMID: 24769243; PMCID: PMC7118997.

Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4

Authors:
Hildick-Smith GJ, Cooney JD, Garone C, Kremer LS, Haack TB, Thon JN, Miyata N, Lieber DS, Calvo SE, Akman HO, Yien YY, Huston NC, Branco DS, Shah DI, Freedman ML, Koehler CM, Italiano JE Jr, Merkenschlager A, Beblo S, Strom TM, Meitinger T, Freisinger P, Donati MA, Prokisch H, Mootha VK, DiMauro S, Paw BH
Citation:
Am J Hum Genet. 2013 Nov 7;93(5):906-14. doi: 10.1016/j.ajhg.2013.09.011. Epub 2013 Oct 10
Epub:
Not Epub
Abstract:
We used exome sequencing to identify mutations in sideroflexin 4 (SFXN4) in two children with mitochondrial disease (the more...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hildick-Smith GJ, Cooney JD, Garone C, Kremer LS, Haack TB, Thon JN, Miyata N, Lieber DS, Calvo SE, Akman HO, Yien YY, Huston NC, Branco DS, Shah DI, Freedman ML, Koehler CM, Italiano JE Jr, Merkenschlager A, Beblo S, Strom TM, Meitinger T, Freisinger P, Donati MA, Prokisch H, Mootha VK, DiMauro S, Paw BH. Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4. Am J Hum Genet. 2013 Nov 7;93(5):906-14. doi: 10.1016/j.ajhg.2013.09.011. Epub 2013 Oct 10.

Genome-wide RNA-binding analysis of the trypanosome U1 snRNP proteins U1C and U1-70K reveals cis/trans-spliceosomal network

Authors:
Preußer C, Rossbach O, Hung L-H, Li D, Bindereif A
Citation:
Nucl Acids Res. 2014;[Epub ahead of print] doi:10.1093/nar/gku286
Epub:
Not Epub
Abstract:
Trans-splicing in trypanosomes adds a 39-nucleotide mini-exon from the spliced leader (SL) RNA to the 5′ end of each protein-...
Delivery Method:
electroporation
Organism or Cell Type:
Trypanosoma brucei 29-13 cells
Citation Extract:
Preußer C, Rossbach O, Hung L-H, Li D, Bindereif A. Genome-wide RNA-binding analysis of the trypanosome U1 snRNP proteins U1C and U1-70K reveals cis/trans-spliceosomal network. Nucl Acids Res. 2014;[Epub ahead of print] doi:10.1093/nar/gku286.

The Asparaginyl Endopeptidase Legumain Is Essential for Functional Recovery after Spinal Cord Injury in Adult Zebrafish

Authors:
Ma L, Shen Y-Q, Khatri HP, Schachner M
Citation:
PLoS ONE. 2014;9(4):e95098. doi:10.1371/journal.pone.0095098
Epub:
Not Epub
Abstract:
Unlike mammals, adult zebrafish are capable of regenerating severed axons and regaining locomotor function after spinal cord...
Delivery Method:
Gelfoam at injury
Organism or Cell Type:
zebrafish
Citation Extract:
Ma L, Shen Y-Q, Khatri HP, Schachner M. The Asparaginyl Endopeptidase Legumain Is Essential for Functional Recovery after Spinal Cord Injury in Adult Zebrafish. PLoS ONE. 2014;9(4):e95098. doi:10.1371/journal.pone.0095098.

A molecular base for cell sorting at embryonic boundaries: contact inhibition of cadherin adhesion by ephrin/ Eph-dependent contractility

Authors:
Fagotto F, Rohani N, Touret AS, Li R
Citation:
Dev Cell. 2013 Oct 14;27(1):72-87. doi: 10.1016/j.devcel.2013.09.004. Epub 2013 Oct 3
Epub:
Not Epub
Abstract:
The mechanism responsible for subdividing the embryo into individual tissues is a fundamental, yet still poorly understood,...
Citation Extract:
Fagotto F, Rohani N, Touret AS, Li R. A molecular base for cell sorting at embryonic boundaries: contact inhibition of cadherin adhesion by ephrin/ Eph-dependent contractility. Dev Cell. 2013 Oct 14;27(1):72-87. doi: 10.1016/j.devcel.2013.09.004. Epub 2013 Oct 3.

Cytoplasmic carboxypeptidase 5 regulates tubulin glutamylation and zebrafish cilia formation and function

Authors:
Pathak N, Austin-Tse CA, Liu Y, Vasilyev A, Drummond IA
Citation:
Mol Biol Cell. 2014 Apr 17. [Epub ahead of print]
Epub:
Yes
Abstract:
Glutamylation is a functionally important tubulin posttranslational modification enriched on stable microtubules of neuronal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pathak N, Austin-Tse CA, Liu Y, Vasilyev A, Drummond IA. Cytoplasmic carboxypeptidase 5 regulates tubulin glutamylation and zebrafish cilia formation and function. Mol Biol Cell. 2014 Apr 17. [Epub ahead of print].

C-terminal COOH of Integrin β1 Is Necessary for β1 Association with the Kindlin-2 Adapter Protein

Authors:
Fitzpatrick P, Shattil SJ, Ablooglu AJ
Citation:
J Biol Chem. 2014;289:11183-111. doi:10.1074/jbc.M113.535369
Epub:
Not Epub
Abstract:
Protein-protein interactions are driving forces in cellular processes. As a prime example, transmembrane integrins link...
Organism or Cell Type:
zebrafish
Citation Extract:
Fitzpatrick P, Shattil SJ, Ablooglu AJ. C-terminal COOH of Integrin β1 Is Necessary for β1 Association with the Kindlin-2 Adapter Protein. J Biol Chem. 2014;289:11183-111. doi:10.1074/jbc.M113.535369 .

Estrogen-related receptor γ is an in vivo receptor of bisphenol A

Authors:
Tohmé M, Prud’homme SM, Boulahtouf A, Samarut E, Brunet F, Bernard L, Bourguet W, Gibert Y, Balaguer P, Laudet V
Citation:
FASEB J. 2014;[Epubl ahead of print] doi:10.1096/fj.13-240465
Epub:
Yes
Abstract:
Bisphenol A (BPA) is an endocrine disruptor that displays estrogenic activity. Several reports suggest that BPA may have...
Organism or Cell Type:
zebrafish
Citation Extract:
Tohmé M, Prud’homme SM, Boulahtouf A, Samarut E, Brunet F, Bernard L, Bourguet W, Gibert Y, Balaguer P, Laudet V. Estrogen-related receptor γ is an in vivo receptor of bisphenol A. FASEB J. 2014;[Epubl ahead of print] doi:10.1096/fj.13-240465 .

Recurrent CNVs and SNVs at the NPHP1 Locus Contribute Pathogenic Alleles to Bardet-Biedl Syndrome

Authors:
Lindstrand A, Davis EE, Carvalho CMB, Pehlivan D, Willer JR, Tsai I-C, Ramanathan S, Zuppan C, Sabo A, Muzny D, Gibbs R, Liu P, Lewis RA, Banin E, Lupski JR, Clark R, Katsanis N
Citation:
Am J Hum Genet. 2014;[Epub ahead ofprint] doi:10.1016/j.ajhg.2014.03.017
Epub:
Yes
Abstract:
Homozygosity for a recurrent 290 kb deletion of NPHP1 is the most frequent cause of isolated nephronophthisis (NPHP) in humans...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lindstrand A, Davis EE, Carvalho CMB, Pehlivan D, Willer JR, Tsai I-C, Ramanathan S, Zuppan C, Sabo A, Muzny D, Gibbs R, Liu P, Lewis RA, Banin E, Lupski JR, Clark R, Katsanis N. Recurrent CNVs and SNVs at the NPHP1 Locus Contribute Pathogenic Alleles to Bardet-Biedl Syndrome. Am J Hum Genet. 2014;[Epub ahead ofprint] doi:10.1016/j.ajhg.2014.03.017.

Uracil-DNA Glycosylase is involved in DNA demethylation and required for embryonic development in the zebrafish embryo

Authors:
Wu D, Chen L, Sun Q, Wu X, Jia S, Meng A
Citation:
J Biol Chem. 2014 Apr 16. [Epub ahead of print]
Epub:
Yes
Abstract:
Uracil DNA glycosylase (Ung) is a component of base excision repair process and has the ability to remove uracil from U:G...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu D, Chen L, Sun Q, Wu X, Jia S, Meng A. Uracil-DNA Glycosylase is involved in DNA demethylation and required for embryonic development in the zebrafish embryo. J Biol Chem. 2014 Apr 16. [Epub ahead of print].

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