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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Transglutaminase Type 2 regulates the Wnt/β-catenin pathway in vertebrates
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Citation:
Cell Death Dis. 2021;12(3):249. doi:10.1038/s41419-021-03485-2 Epub:
Not Epub Abstract:
TG2 is a multifunctional enzyme involved in several cellular processes and has emerging as a potential regulator of gene... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rossin F, Costa R, Bordi M, D’Eletto M, Occhigrossi L, Farrace MG, Barlev N, Ciccosanti F, Muccioli S, Chieregato L, Szabo I, Fimia GM, Piacentini M, Leanza L. Transglutaminase Type 2 regulates the Wnt/β-catenin pathway in vertebrates. Cell Death Dis. 2021;12(3):249. doi:10.1038/s41419-021-03485-2. |
Adherens junctions are involved in polarized contractile ring formation in dividing epithelial cells of Xenopus laevis embryos
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Citation:
Exp Cell Res. 2021:112525. doi:10.1016/j.yexcr.2021.112525 Epub:
Not Epub Abstract:
Cells dividing in the plane of epithelial tissues proceed by polarized constriction of the actomyosin contractile ring, leading... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Hatte G, Prigent C, Tassan J-P. Adherens junctions are involved in polarized contractile ring formation in dividing epithelial cells of Xenopus laevis embryos. Exp Cell Res. 2021:112525. doi:10.1016/j.yexcr.2021.112525. |
Modular Synthesis of Trifunctional Peptide-oligonucleotide Conjugates via Native Chemical Ligation
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Citation:
Front Chem. 2021;9:9. doi:10.3389/fchem.2021.627329 Epub:
Not Epub Abstract:
Cell penetrating peptides (CPPs) are being increasingly used as efficient vectors for intracellular delivery of biologically... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: spinal muscular atrophy (SMA) patient fibroblasts Citation Extract: Dastpeyman M, Karas JA, Amin A, Turner BJ, Shabanpoor F. Modular Synthesis of Trifunctional Peptide-oligonucleotide Conjugates via Native Chemical Ligation. Front Chem. 2021;9:9. doi:10.3389/fchem.2021.627329. |
hnRNP L is essential for myogenic differentiation and modulates myotonic dystrophy pathologies
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Citation:
Muscle Nerve. 2021 Mar 2. doi: 10.1002/mus.27216. Online ahead of print Epub:
Yes Abstract:
Introduction/aims: RNA binding proteins (RBPs) play an important role in skeletal muscle development and disease by regulating... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Alexander MS, Hightower RM, Reid AL, Bennett AH, Iyer L, Slonim DK, Saha M, Kawahara G, Kunkel LM, Kopin AS, Gupta VA, Kang PB, Draper I. hnRNP L is essential for myogenic differentiation and modulates myotonic dystrophy pathologies. Muscle Nerve. 2021 Mar 2. doi: 10.1002/mus.27216. Online ahead of print. |
Tdrd3 regulates the progression of meiosis II through translational control of Emi2 mRNA in mouse oocytes
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.17.431574 Epub:
Not Epub Abstract:
After completion of meiosis I, the oocyte immediately enters meiosis II and forms a metaphase II (MII) spindle without an... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Takei N, Sato K, Takada Y, Iyyappan R, Susor A, Yamamoto T, Kotani T. Tdrd3 regulates the progression of meiosis II through translational control of Emi2 mRNA in mouse oocytes. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.17.431574. |
Mechanically Sensitive HSF1 is a Key Regulator of Left-Right Symmetry Breaking in Zebrafish Embryos
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.25.432863 Epub:
Not Epub Abstract:
The left-right symmetry breaking of vertebrate embryos requires fluid flow (called nodal flow in zebrafish). However, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Du J, Li SK, Guan L-Y, Guo Z, Yin J-F, Gao L, Kawanishi T, Shimada A, Zhang Q-p, Zheng L-S, Liu Y-Y, Feng X-X, Chen D-Y, Takeda H, Fan Y. Mechanically Sensitive HSF1 is a Key Regulator of Left-Right Symmetry Breaking in Zebrafish Embryos. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.25.432863 . |
Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.24.432660 Epub:
Not Epub Abstract:
The developmental strategies used by progenitor cells to endure a safe journey from their induction place towards the site of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pulgar E, Schwayer C, Guerrero N, López L, Márquez S, Härtel S, Soto R, Heisenberg CP, Concha ML. Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.24.432660 . |
Dlc1 controls cardio-vascular development downstream of Vegfa/Kdrl/Nrp1 signaling in the zebrafish embryo
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.11.430763 Epub:
Not Epub Abstract:
The family of deleted-in-liver-cancer (dlc) genes encodes RhoGTPases and plays pivotal roles in cardiovascular development, but... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Linnerz T, Bertrand JY. Dlc1 controls cardio-vascular development downstream of Vegfa/Kdrl/Nrp1 signaling in the zebrafish embryo. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.11.430763. |
Excessive R-loops trigger an inflammatory cascade leading to increased HSPC production
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Citation:
Dev Cell. 2021 Mar 8;56(5):627-640.e5. doi: 10.1016/j.devcel.2021.02.006. Epub 2021 Mar 1 Epub:
Yes Abstract:
Hematopoietic stem and progenitor cells (HSPCs) arise during embryonic development and are essential for sustaining the blood... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Weinreb JT, Ghazale N, Pradhan K, Gupta V, Potts KS, Tricomi B, Daniels NJ, Padgett RA, De Oliveira S, Verma A, Bowman TV. Excessive R-loops trigger an inflammatory cascade leading to increased HSPC production. Dev Cell. 2021 Mar 8;56(5):627-640.e5. doi: 10.1016/j.devcel.2021.02.006. Epub 2021 Mar 1. |
Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns
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Citation:
Nucl Acids Res. 2021;gkab118. doi:10.1093/nar/gkab118 Epub:
Not Epub Abstract:
Vertebrate genomes contain major (>99.5%) and minor (<0.5%) introns that are spliced by the major and minor spliceosomes... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HEK293T Citation Extract: Olthof AM, White AK, Mieruszynski S, Doggett K, Lee MF, Chakroun A, Abdel Aleem AK, Rousseau J, Magnani C, Roifman CM, Campeau PM, Heath JK, Kanadia RN. Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns. Nucl Acids Res. 2021;gkab118. doi:10.1093/nar/gkab118. |