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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation
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Citation:
PLoS Genet. 2021;17(3):e1009263. doi:10.1371/journal.pgen.1009263 Epub:
Not Epub Abstract:
Eukaryotic gene expression is extensively regulated by cellular stress and pathogen infections. We have previously shown that... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HEK293 Citation Extract: Wang X, Liu L, Whisnant AW, Hennig T, Djakovic L, Haque N, Bach C, Sandri-Goldin RM, Erhard F, Friedel CC, Dölken L, Shi Y. Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation. PLoS Genet. 2021;17(3):e1009263. doi:10.1371/journal.pgen.1009263. |
Stepwise candidate drug screening for myopia control by using zebrafish, mouse, and Golden Syrian Hamster myopia models
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Citation:
EBioMedicine. 2021;65:103263. doi:10.1016/j.ebiom.2021.103263 Epub:
Not Epub Abstract:
Background: We developed a preclinical protocol for the screening of candidate drugs able to control myopia and prevent its... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin M-Y, Lin I-T, Wu Y-C, Wang I-J. Stepwise candidate drug screening for myopia control by using zebrafish, mouse, and Golden Syrian Hamster myopia models. EBioMedicine. 2021;65:103263. doi:10.1016/j.ebiom.2021.103263. |
Conditional gene knockdowns in sea urchins using caged morpholinos
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Citation:
Dev Biol . 2021 Mar 5;475:21-29. doi: 10.1016/j.ydbio.2021.02.014 Epub:
Not Epub Abstract:
Sea urchins and other echinoderms are important experimental models for analyzing embryonic development, but a lack of spatial... Delivery Method:
microinjection Organism or Cell Type:
sea urchin Citation Extract: Bardhan A, Deiters A, Ettensohn CA. Conditional gene knockdowns in sea urchins using caged morpholinos. Dev Biol . 2021 Mar 5;475:21-29. doi: 10.1016/j.ydbio.2021.02.014. |
The altered expression of neurofilament in mouse models and patients with spinal muscular atrophy
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Citation:
Ann Clin Transl Neurol. 2021 Mar 8. doi: 10.1002/acn3.51336. Online ahead of print Epub:
Not Epub Abstract:
Objectives: To investigate the levels of neurofilaments (NFs) in transgenic mice and patients with spinal muscular atrophy (SMA... Delivery Method:
subcutaneous (s.c.) injection Organism or Cell Type:
severe SMA mice Citation Extract: Spicer C, Lu CH, Catapano F, Scoto M, Zaharieva I, Malaspina A, Morgan JE, Greensmith L, Muntoni F, Zhou H. The altered expression of neurofilament in mouse models and patients with spinal muscular atrophy. Ann Clin Transl Neurol. 2021 Mar 8. doi: 10.1002/acn3.51336. Online ahead of print. |
Knockdown of hspg2 is associated with abnormal mandibular joint formation and neural crest cell dysfunction in zebrafish
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Citation:
BMC Dev Biol. 2021 Mar 8;21(1):7. doi: 10.1186/s12861-021-00238-4 Epub:
Not Epub Abstract:
Background: Heparan sulfate proteoglycan 2 (HSPG2) encodes for perlecan, a large proteoglycan that plays an important role in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Castellanos BS, Reyes-Nava NG, Quintana AM. Knockdown of hspg2 is associated with abnormal mandibular joint formation and neural crest cell dysfunction in zebrafish. BMC Dev Biol. 2021 Mar 8;21(1):7. doi: 10.1186/s12861-021-00238-4. |
Na+/H+-exchangers differentially contribute to midgut fluid sodium and proton concentration in the sea urchin larva
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Citation:
J Exp Biol. 2021 Apr 1;224(7):jeb240705. doi: 10.1242/jeb.240705. Epub 2021 Apr 15 Epub:
Not Epub Abstract:
Regulation of ionic composition and pH is a requisite of all digestive systems in the animal kingdom. Larval stages of the... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Petersen I, Chang WWJ, Hu MY. Na+/H+-exchangers differentially contribute to midgut fluid sodium and proton concentration in the sea urchin larva. J Exp Biol. 2021 Apr 1;224(7):jeb240705. doi: 10.1242/jeb.240705. Epub 2021 Apr 15. |
Antiviral Activity of a New Class of Chemically Modified Antisense Oligonucleotides against Influenza А Virus
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Citation:
Russ J Bioorg Chem. 2019;45(6):774-782. doi:10.1134/S1068162019060268 Epub:
Not Epub Abstract:
The paper reports the synthesis of a series of antisense oligonucleotides (aONs) directed against different segments of the... Delivery Method:
Endo-Porter, scrape delivery Organism or Cell Type:
cell culture: (H1N1)/MDCK, (H1N1)/A549 influenza in cells Citation Extract: Markov AV, Kupryushkin MS, Goncharova EP, Amirkhanov RN, Vasilyeva SV, Pyshnyi DV, Zenkova MA, Logashenko EB. Antiviral Activity of a New Class of Chemically Modified Antisense Oligonucleotides against Influenza А Virus. Russ J Bioorg Chem. 2019;45(6):774-782. doi:10.1134/S1068162019060268. |
Human-specific staphylococcal virulence factors enhance pathogenicity in a humanised zebrafish C5a receptor model
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Citation:
J Cell Sci. 2021;134:jcs252205 doi:10.1242/jcs.252205 Epub:
Not Epub Abstract:
Staphylococcus aureus infects ∼30% of the human population and causes a spectrum of pathologies ranging from mild skin... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Buchan KD, van Gent M, Prajsnar TK, Ogryzko NV, de Jong NWM, Kolata J, Foster SJ, van Strijp JAG, Renshaw SA. Human-specific staphylococcal virulence factors enhance pathogenicity in a humanised zebrafish C5a receptor model. J Cell Sci. 2021;134:jcs252205 doi:10.1242/jcs.252205. |
Novel Dioxane and Morpholino Nucleotide Analogues: Syntheses and RNA-Hybridization Properties
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Citation:
Chembiochem. 2020 Oct 28. doi: 10.1002/cbic.202000693 Epub:
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A novel class of nucleotide analogues with a dioxane ring as central scaffold has been developed. Synthetic routes in two... Citation Extract: Hofmeister A, Jahn-Hofmann K, Krack A, Müller A, Kurz M, Scheidler S. Novel Dioxane and Morpholino Nucleotide Analogues: Syntheses and RNA-Hybridization Properties. Chembiochem. 2020 Oct 28. doi: 10.1002/cbic.202000693. |
Jagged–Notch-mediated divergence of immune cell crosstalk maintains the anti-inflammatory response in visceral leishmaniasis
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Citation:
J Cell Sci. 2021;134:jcs252494 doi:10.1242/jcs.252494 Epub:
Not Epub Abstract:
Notch signaling governs crucial aspects of intercellular communication spanning antigen-presenting cells and T-cells. In this... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Balb/c mice and sometimes Leishmania donovani infections Citation Extract: Chandrakar P, Seth A, Rani A, Dutta M, Parmar N, Descoteaux A, Kar S. Jagged–Notch-mediated divergence of immune cell crosstalk maintains the anti-inflammatory response in visceral leishmaniasis. J Cell Sci. 2021;134:jcs252494 doi:10.1242/jcs.252494 . |