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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers for In Situ Live-Cell Molecular Imaging of Dengue Virus Replication

Authors:
Victorio CB, Novera W, Tham JY, Watanabe S, Vasudevan SG, Chacko A-M
Citation:
Int J Molec Sci. 2020;21(23):1422-0067 doi:10.3390/ijms21239260
Epub:
Not Epub
Abstract:
Current methods to detect and monitor pathogens in biological systems are largely limited by the tradeoffs between spatial...
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: Vero, BHK-21
Citation Extract:
Victorio CB, Novera W, Tham JY, Watanabe S, Vasudevan SG, Chacko A-M. Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers for In Situ Live-Cell Molecular Imaging of Dengue Virus Replication. Int J Molec Sci. 2020;21(23):1422-0067 doi:10.3390/ijms21239260.

The N-glycome regulates the endothelial-to-hematopoietic transition

Authors:
Kasper DM, Hintzen J, Wu Y, Ghersi JJ, Mandl HK, Salinas KE, Armero W, He Z, Sheng Y, Xie Y, Heindel DW, Park EJ, William C. Sessa WC, Mahal LK, Lebrilla C, Hirschi KK, Nicoli S
Citation:
Science. 2020:370(6521):1186-1191. doi:10.1126/science.aaz2121
Epub:
Not Epub
Abstract:
Definitive hematopoietic stem and progenitor cells (HSPCs) arise from the transdifferentiation of hemogenic endothelial cells (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kasper DM, Hintzen J, Wu Y, Ghersi JJ, Mandl HK, Salinas KE, Armero W, He Z, Sheng Y, Xie Y, Heindel DW, Park EJ, William C. Sessa WC, Mahal LK, Lebrilla C, Hirschi KK, Nicoli S. The N-glycome regulates the endothelial-to-hematopoietic transition. Science. 2020:370(6521):1186-1191. doi:10.1126/science.aaz2121.

Unravelling the developmental and functional significance of an ancient Argonaute duplication

Authors:
Fridrich A, Modepalli V, Lewandowska M, Aharoni R, Moran Y
Citation:
Nat Comm. 2020;11:6187. doi:10.1038/s41467-020-20003-8
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) base-pair to messenger RNA targets and guide Argonaute proteins to mediate their silencing. This target...
Organism or Cell Type:
Nematostella vectensis (cniderian)
Citation Extract:
Fridrich A, Modepalli V, Lewandowska M, Aharoni R, Moran Y. Unravelling the developmental and functional significance of an ancient Argonaute duplication. Nat Comm. 2020;11:6187. doi:10.1038/s41467-020-20003-8.

Histone H4K20 methylation synchronizes cytoskeletal dynamics with cell cycle phases during epidermal differentiation

Authors:
Angerilli A, Tait J, Berges J, Shcherbakova I, Schauer T, Smialowski P, Hsam O, Mentele E, Nicetto D, Rupp RAW
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.12.01.404053
Epub:
Not Epub
Abstract:
Histone tails are subject to various post-translational modifications, which play a fundamental role in altering chromatin...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis, Xenopus tropicalis
Citation Extract:
Angerilli A, Tait J, Berges J, Shcherbakova I, Schauer T, Smialowski P, Hsam O, Mentele E, Nicetto D, Rupp RAW. Histone H4K20 methylation synchronizes cytoskeletal dynamics with cell cycle phases during epidermal differentiation. bioRxiv. 2020;[preprint] doi:10.1101/2020.12.01.404053 .

Pax9 is essential for granulopoiesis but dispensable for erythropoiesis in zebrafish

Authors:
Pak B, Schmitt CE, Oh S, Kim JD, Choi W, Han O, Kim M, Kim MJ, Ham HJ, Kim S, Huh TL, Kim JI, Jin SW
Citation:
Biochem Biophys Res Commun. 2020 Nov 27:S0006-291X(20)32121-5. doi: 10.1016/j.bbrc.2020.11.077. Online ahead of print
Epub:
Yes
Abstract:
Paired Box (Pax) gene family, a group of transcription regulators have been implicated in diverse physiological processes....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pak B, Schmitt CE, Oh S, Kim JD, Choi W, Han O, Kim M, Kim MJ, Ham HJ, Kim S, Huh TL, Kim JI, Jin SW. Pax9 is essential for granulopoiesis but dispensable for erythropoiesis in zebrafish. Biochem Biophys Res Commun. 2020 Nov 27:S0006-291X(20)32121-5. doi: 10.1016/j.bbrc.2020.11.077. Online ahead of print.

Istaroxime treatment ameliorates calcium dysregulation in a zebrafish model for Phospholamban R14del cardiomyopathy

Authors:
Kamel SM, van Opbergen CJM, Koopman CD, Verkerk AO, Onderwater YL, Chocron S, Polidoro Pontalti C, Vos MA, de Boer TP, van Veen TAB, Bakkers J
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.25.397422
Epub:
Not Epub
Abstract:
The heterozygous phospholamban (PLN) p.Arg14del (R14del) mutation is found in patients with dilated or arrhythmogenic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kamel SM, van Opbergen CJM, Koopman CD, Verkerk AO, Onderwater YL, Chocron S, Polidoro Pontalti C, Vos MA, de Boer TP, van Veen TAB, Bakkers J. Istaroxime treatment ameliorates calcium dysregulation in a zebrafish model for Phospholamban R14del cardiomyopathy. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.25.397422.

Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation

Authors:
Wang X, Liu L, Whisnant AW, Hennig T, Djakovic L, Haque N, Bach C, Sandri-Goldin RM, Erhard F, Friedel CC, Dölken L, Shi Y
Citation:
PLoS Genet. 2021 Mar 8;17(3):e1009263. doi: 10.1371/journal.pgen.1009263. PMID: 33684133; PMCID: PMC7971895.
Epub:
Not Epub
Abstract:
Eukaryotic gene expression is extensively regulated by cellular stress and pathogen infections. We have previously shown that...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HEK293
Citation Extract:
Wang X, Liu L, Whisnant AW, Hennig T, Djakovic L, Haque N, Bach C, Sandri-Goldin RM, Erhard F, Friedel CC, Dölken L, Shi Y. Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation. PLoS Genet. 2021 Mar 8;17(3):e1009263. doi: 10.1371/journal.pgen.1009263. PMID: 33684133; PMCID: PMC7971895..

H2S promotes developmental brain angiogenesis via the NOS/NO pathway in zebrafish

Authors:
Jiang W, Liu C, Deng M, Wang F, Ren X, Fan Y, Du J, Wang Y
Citation:
Stroke Vasc Neurol. 2020 Nov 27:svn-2020-000584. doi: 10.1136/svn-2020-000584. Online ahead of print
Epub:
Yes
Abstract:
Background: Hydrogen sulphide (H2S) is considered as the third member of the gasotransmitter family, along with nitric oxide (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jiang W, Liu C, Deng M, Wang F, Ren X, Fan Y, Du J, Wang Y. H2S promotes developmental brain angiogenesis via the NOS/NO pathway in zebrafish. Stroke Vasc Neurol. 2020 Nov 27:svn-2020-000584. doi: 10.1136/svn-2020-000584. Online ahead of print.

Abnormal Vasculature Development in Zebrafish Embryos with Reduced Expression of Pantothenate Kinase 2 Gene

Authors:
Khatri D, Mignani L, Zizioli D, Ritelli M, Monti E, Finazzi D
Citation:
Bull Exp Biol Med. 2020 Nov 25. doi: 10.1007/s10517-020-05004-3. Online ahead of print
Epub:
Yes
Abstract:
Mutations in pank2 gene encoding pantothenate kinase 2 determine a pantothenate kinase-associated neurodegeneration, a rare...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Khatri D, Mignani L, Zizioli D, Ritelli M, Monti E, Finazzi D. Abnormal Vasculature Development in Zebrafish Embryos with Reduced Expression of Pantothenate Kinase 2 Gene. Bull Exp Biol Med. 2020 Nov 25. doi: 10.1007/s10517-020-05004-3. Online ahead of print.

Loss of ITGB3 in Ovine Conceptuses Decreases Conceptus Expression of NOS3 and SPP1: Implications for the Developing Placental Vasculature†

Authors:
Frank JW, Steinhauser CB, Wang X, Burghardt RC, Bazer FW, Johnson GA
Citation:
Biol Reprod. 2020;[Epub ahead of print] doi:10.1093/biolre/ioaa212
Epub:
Yes
Abstract:
During the peri-implantation period of pregnancy in sheep there is an initial period of loose apposition of the elongating...
Organism or Cell Type:
Ovis aries (sheep)
Citation Extract:
Frank JW, Steinhauser CB, Wang X, Burghardt RC, Bazer FW, Johnson GA. Loss of ITGB3 in Ovine Conceptuses Decreases Conceptus Expression of NOS3 and SPP1: Implications for the Developing Placental Vasculature†. Biol Reprod. 2020;[Epub ahead of print] doi:10.1093/biolre/ioaa212.

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