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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Conserved IL-2Rγc Signaling Mediates Lymphopoiesis in Zebrafish

Authors:
Sertori R, Liongue C, Basheer F, Lewis KL, Rasighaemi P, de Coninck D, Traver D, Ward AC
Citation:
J Immunol. 2016 Jan 1;196(1):135-43. doi: 10.4049/jimmunol.1403060. Epub 2015 Nov 20
Epub:
Not Epub
Abstract:
The IL-2 receptor γ common (IL-2Rγc) chain is the shared subunit of the receptors for the IL-2 family of cytokines, which...
Link:
https://www.jimmunol.org/content/196/1/135.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sertori R, Liongue C, Basheer F, Lewis KL, Rasighaemi P, de Coninck D, Traver D, Ward AC. Conserved IL-2Rγc Signaling Mediates Lymphopoiesis in Zebrafish. J Immunol. 2016 Jan 1;196(1):135-43. doi: 10.4049/jimmunol.1403060. Epub 2015 Nov 20.

LSD1/KDM1A promotes hematopoietic commitment of hemangioblasts through downregulation of Etv2

Authors:
Takeuchi M, Fuse Y, Watanabe M, Andrea CS, Takeuchi M, Nakajima H, Ohashi K, Kaneko H, Kobayashi-Osaki M, Yamamoto M, Kobayashi M
Citation:
Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13922-7. doi: 10.1073/pnas.1517326112. Epub 2015 Oct 28
Epub:
Not Epub
Abstract:
The hemangioblast is a progenitor cell with the capacity to give rise to both hematopoietic and endothelial progenitors....
Link:
https://www.pnas.org/content/112/45/13922.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Takeuchi M, Fuse Y, Watanabe M, Andrea CS, Takeuchi M, Nakajima H, Ohashi K, Kaneko H, Kobayashi-Osaki M, Yamamoto M, Kobayashi M. LSD1/KDM1A promotes hematopoietic commitment of hemangioblasts through downregulation of Etv2. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13922-7. doi: 10.1073/pnas.1517326112. Epub 2015 Oct 28.

A role for nitric oxide in the control of breathing in zebrafish (Danio rerio)

Authors:
Porteus CS, Pollack J, Tzaneva V, Kwong RW, Kumai Y, Abdallah SJ, Zaccone G, Lauriano ER, Milsom WK, Perry SF
Citation:
J Exp Biol. 2015 Dec;218(Pt 23):3746-53. doi: 10.1242/jeb.127795. Epub 2015 Oct 20
Epub:
Not Epub
Abstract:
Nitric oxide (NO) is a gaseous neurotransmitter, which, in adult mammals, modulates the acute hypoxic ventilatory response; its...
Link:
https://jeb.biologists.org/content/218/23/3746.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Porteus CS, Pollack J, Tzaneva V, Kwong RW, Kumai Y, Abdallah SJ, Zaccone G, Lauriano ER, Milsom WK, Perry SF. A role for nitric oxide in the control of breathing in zebrafish (Danio rerio). J Exp Biol. 2015 Dec;218(Pt 23):3746-53. doi: 10.1242/jeb.127795. Epub 2015 Oct 20.

lin28 proteins promote expression of 17∼92 family miRNAs during amphibian development

Authors:
Warrander F, Faas L, Kovalevskiy O, Peters D, Coles M, Antson AA, Genever P, Isaacs HV
Citation:
Dev Dyn. 2016 Jan;245(1):34-46. doi: 10.1002/dvdy.24358. Epub 2015 Nov 14
Epub:
Not Epub
Abstract:
BACKGROUND: Lin28 proteins are post-transcriptional regulators of gene expression with multiple roles in development and the...
Link:
https://anatomypubs.onlinelibrary.wiley.com/doi/full/10.1002/dvdy.24358
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Warrander F, Faas L, Kovalevskiy O, Peters D, Coles M, Antson AA, Genever P, Isaacs HV. lin28 proteins promote expression of 17∼92 family miRNAs during amphibian development. Dev Dyn. 2016 Jan;245(1):34-46. doi: 10.1002/dvdy.24358. Epub 2015 Nov 14.

Esco2 regulates cx43 expression during skeletal regeneration in the zebrafish fin

Authors:
Banerji R, Eble DM, Iovine MK, Skibbens RV
Citation:
Dev Dyn. 2016 Jan;245(1):7-21. doi: 10.1002/dvdy.24354. Epub 2015 Nov 25
Epub:
Not Epub
Abstract:
Background: Roberts syndrome (RBS) is a rare genetic disorder characterized by craniofacial abnormalities, limb malformation,...
Link:
https://anatomypubs.onlinelibrary.wiley.com/doi/full/10.1002/dvdy.24354
Delivery Method:
injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Banerji R, Eble DM, Iovine MK, Skibbens RV. Esco2 regulates cx43 expression during skeletal regeneration in the zebrafish fin. Dev Dyn. 2016 Jan;245(1):7-21. doi: 10.1002/dvdy.24354. Epub 2015 Nov 25.

The Proto-oncogene Transcription Factor Ets1 Regulates Neural Crest Development through Histone Deacetylase 1 to Mediate Output of Bone Morphogenetic Protein Signaling

Authors:
Wang C, Kam RK, Shi W, Xia Y, Chen X, Cao Y, Sun J, Du Y, Lu G, Chen Z, Chan WY, Chan SO, Deng Y, Zhao H
Citation:
J Biol Chem. 2015 Sep 4;290(36):21925-38. doi: 10.1074/jbc.M115.644864. Epub 2015 Jul 20
Epub:
Not Epub
Abstract:
The neural crest (NC) is a transient, migratory cell population that differentiates into a large variety of tissues including...
Link:
https://www.jbc.org/content/290/36/21925.long
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Wang C, Kam RK, Shi W, Xia Y, Chen X, Cao Y, Sun J, Du Y, Lu G, Chen Z, Chan WY, Chan SO, Deng Y, Zhao H. The Proto-oncogene Transcription Factor Ets1 Regulates Neural Crest Development through Histone Deacetylase 1 to Mediate Output of Bone Morphogenetic Protein Signaling. J Biol Chem. 2015 Sep 4;290(36):21925-38. doi: 10.1074/jbc.M115.644864. Epub 2015 Jul 20.

G protein-coupled receptors Flop1 and Flop2 inhibit Wnt/β-catenin signaling and are essential for head formation in Xenopus

Authors:
Miyagi A, Negishi T, Yamamoto TS, Ueno N
Citation:
Dev Biol. 2015 Nov 1;407(1):131-44. doi: 10.1016/j.ydbio.2015.08.001. Epub 2015 Aug 3
Epub:
Not Epub
Abstract:
Patterning of the vertebrate anterior–posterior axis is regulated by the coordinated action of growth factors whose effects can...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160615300981
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Miyagi A, Negishi T, Yamamoto TS, Ueno N. G protein-coupled receptors Flop1 and Flop2 inhibit Wnt/β-catenin signaling and are essential for head formation in Xenopus. Dev Biol. 2015 Nov 1;407(1):131-44. doi: 10.1016/j.ydbio.2015.08.001. Epub 2015 Aug 3.

TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells

Authors:
Bestle D, Heindl MR, Limburg H, Van Lam van T, Pilgram O, Moulton H, Stein DA, Hardes K, Eickmann M, Dolnik O, Rohde C, Klenk HD, Garten W, Steinmetzer T, Böttcher-Friebertshäuser E
Citation:
Life Sci Alliance. 2020 Jul 23;3(9):e202000786. doi: 10.26508/lsa.202000786. PMID: 32703818; PMCID: PMC7383062
Epub:
Not Epub
Abstract:
The novel emerged SARS-CoV-2 has rapidly spread around the world causing acute infection of the respiratory tract (COVID-19)...
Link:
https://www.life-science-alliance.org/content/3/9/e202000786
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: Calu-3
Citation Extract:
Bestle D, Heindl MR, Limburg H, Van Lam van T, Pilgram O, Moulton H, Stein DA, Hardes K, Eickmann M, Dolnik O, Rohde C, Klenk HD, Garten W, Steinmetzer T, Böttcher-Friebertshäuser E. TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells. Life Sci Alliance. 2020 Jul 23;3(9):e202000786. doi: 10.26508/lsa.202000786. PMID: 32703818; PMCID: PMC7383062.

Knockdown of poc1b causes abnormal photoreceptor sensory cilium and vision impairment in zebrafish

Authors:
Zhang C, Zhang Q, Wang F, Liu Q
Citation:
Biochem Biophys Res Commun. 2015 Oct 2;465(4):651-7. doi: 10.1016/j.bbrc.2015.06.083. Epub 2015 Jul 15
Epub:
Not Epub
Abstract:
Proteomic analysis of the mouse photoreceptor sensory cilium identified a set of cilia proteins, including Poc1 centriolar...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0006291X15301364
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang C, Zhang Q, Wang F, Liu Q. Knockdown of poc1b causes abnormal photoreceptor sensory cilium and vision impairment in zebrafish. Biochem Biophys Res Commun. 2015 Oct 2;465(4):651-7. doi: 10.1016/j.bbrc.2015.06.083. Epub 2015 Jul 15.

Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling

Authors:
Zhou Z, Yao X, Li S, Xiong Y, Dong X, Zhao Y, Jiang J, Zhang Q
Citation:
Dev Cell. 2015 Jul 6;34(1):58-72. doi: 10.1016/j.devcel.2015.05.016. Epub 2015 Jun 25
Epub:
Not Epub
Abstract:
Hedgehog (Hh) signaling plays essential roles in animal development and tissue homeostasis, and its misregulation causes...
Link:
https://www.cell.com/developmental-cell/fulltext/S1534-5807(15)00352-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou Z, Yao X, Li S, Xiong Y, Dong X, Zhao Y, Jiang J, Zhang Q. Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling. Dev Cell. 2015 Jul 6;34(1):58-72. doi: 10.1016/j.devcel.2015.05.016. Epub 2015 Jun 25.

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