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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Cdc42 Effector Protein 3 Interacts With Cdc42 in Regulating Xenopus Somite Segmentation

Authors:
Kho M, Shi H, Nie S
Citation:
Front Physiol. 2019 May 7;10:542. doi: 10.3389/fphys.2019.00542. eCollection 2019
Epub:
Not Epub
Abstract:
Somitogenesis is a critical process during vertebrate development that establishes the segmented body plan and gives rise to...
Link:
https://www.frontiersin.org/articles/10.3389/fphys.2019.00542/full
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kho M, Shi H, Nie S. Cdc42 Effector Protein 3 Interacts With Cdc42 in Regulating Xenopus Somite Segmentation. Front Physiol. 2019 May 7;10:542. doi: 10.3389/fphys.2019.00542. eCollection 2019.

Coupling Genome-wide Transcriptomics and Developmental Toxicity Profiles in Zebrafish to Characterize Polycyclic Aromatic Hydrocarbon (PAH) Hazard

Authors:
Shankar P, Geier MC, Truong L, McClure RS, Pande P, Waters KM, Tanguay RL
Citation:
Int J Mol Sci. 2019 May 25;20(10). pii: E2570. doi: 10.3390/ijms20102570
Epub:
Not Epub
Abstract:
Polycyclic Aromatic Hydrocarbons (PAHs) are diverse environmental pollutants associated with adverse human health effects. Many...
Link:
https://www.mdpi.com/1422-0067/20/10/2570
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shankar P, Geier MC, Truong L, McClure RS, Pande P, Waters KM, Tanguay RL. Coupling Genome-wide Transcriptomics and Developmental Toxicity Profiles in Zebrafish to Characterize Polycyclic Aromatic Hydrocarbon (PAH) Hazard. Int J Mol Sci. 2019 May 25;20(10). pii: E2570. doi: 10.3390/ijms20102570.

Involvement of Myt1 kinase in the G2 phase of the first cell cycle in Xenopus laevis

Authors:
Yoshitome S, Aiba Y, Yuge M, Furuno N, Watanabe M, Nakajo N
Citation:
Biochem Biophys Res Commun. 2019 May 23. pii: S0006-291X(19)30990-8. doi: 10.1016/j.bbrc.2019.05.104. [Epub ahead of print]
Epub:
Yes
Abstract:
During cleavage of Xenopus laevis, the first mitotic cell cycle immediately following fertilization is approximately 90 min and...
Link:
https://www.sciencedirect.com/science/article/pii/S0006291X19309908
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yoshitome S, Aiba Y, Yuge M, Furuno N, Watanabe M, Nakajo N. Involvement of Myt1 kinase in the G2 phase of the first cell cycle in Xenopus laevis. Biochem Biophys Res Commun. 2019 May 23. pii: S0006-291X(19)30990-8. doi: 10.1016/j.bbrc.2019.05.104. [Epub ahead of print].

Wnt11 regulates cardiac chamber development and disease during perinatal maturation

Authors:
Touma M, Kang X, Gao F, Zhao Y, Cass AA, Biniwale R, Xiao X, Eghbali M, Coppola G, Reemtsen B, Wang Y
Citation:
JCI Insight. 2017 Sep 7;2(17). pii: 94904. doi: 10.1172/jci.insight.94904. eCollection 2017 Sep 7
Epub:
Not Epub
Abstract:
Ventricular chamber growth and development during perinatal circulatory transition is critical for functional adaptation of the...
Link:
https://insight.jci.org/articles/view/94904
Delivery Method:
maternal i.v. for embryo delivery, Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Touma M, Kang X, Gao F, Zhao Y, Cass AA, Biniwale R, Xiao X, Eghbali M, Coppola G, Reemtsen B, Wang Y. Wnt11 regulates cardiac chamber development and disease during perinatal maturation. JCI Insight. 2017 Sep 7;2(17). pii: 94904. doi: 10.1172/jci.insight.94904. eCollection 2017 Sep 7.

Changes in Thyroid Hormone Activity Disrupt Photomotor Behavior of Larval Zebrafish

Authors:
Walter KM, Miller GW, Chen X, Harvey DJ, Puschner B, Lein PJ
Citation:
Neurotoxicology. 2019 May 20. pii: S0161-813X(19)30048-8. doi: 10.1016/j.neuro.2019.05.008. [Epub ahead of print]
Epub:
Yes
Abstract:
High throughput in vitro, in silico, and computational approaches have identified numerous environmental chemicals that...
Link:
https://www.sciencedirect.com/science/article/pii/S0161813X19300488
Organism or Cell Type:
zebrafish
Citation Extract:
Walter KM, Miller GW, Chen X, Harvey DJ, Puschner B, Lein PJ. Changes in Thyroid Hormone Activity Disrupt Photomotor Behavior of Larval Zebrafish. Neurotoxicology. 2019 May 20. pii: S0161-813X(19)30048-8. doi: 10.1016/j.neuro.2019.05.008. [Epub ahead of print].

AcrAB-TolC Inhibition by Peptide-conjugated Phosphorodiamidate Morpholino Oligomers Restores Antibiotic Activity in vitro and in vivo

Authors:
Sturge CR, Felder-Scott CF, Pifer R, Pybus C, Jain R, Geller B, Greenberg D
Citation:
ACS Infect Dis. 2019 May 23. doi: 10.1021/acsinfecdis.9b00123. [Epub ahead of print]
Epub:
Yes
Abstract:
Overexpression of bacterial efflux pumps are a driver of increasing antibiotic resistance in gram-negative pathogens. The AcrAB...
Link:
https://pubs.acs.org/doi/10.1021/acsinfecdis.9b00123
Delivery Method:
peptide-linked
Organism or Cell Type:
Enterobacteriaceae strains, Klebsiella pneumoniae, Pseudomonas aeruginosa
Citation Extract:
Sturge CR, Felder-Scott CF, Pifer R, Pybus C, Jain R, Geller B, Greenberg D. AcrAB-TolC Inhibition by Peptide-conjugated Phosphorodiamidate Morpholino Oligomers Restores Antibiotic Activity in vitro and in vivo. ACS Infect Dis. 2019 May 23. doi: 10.1021/acsinfecdis.9b00123. [Epub ahead of print].

EvpP inhibits neutrophils recruitment via Jnk-caspy inflammasome signaling in vivo

Authors:
Tan J, Yang D, Wang Z, Zheng X, Zhang Y, Liu Q
Citation:
Fish & Shellfish Immunol. 2019;[Epub ahead of print] doi:10.1016/j.fsi.2019.05.051
Epub:
Yes
Abstract:
Innate immunity is regulated by phagocytic cells and is critical for host control of bacterial infection. In many bacteria, the...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1050464819306187
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tan J, Yang D, Wang Z, Zheng X, Zhang Y, Liu Q. EvpP inhibits neutrophils recruitment via Jnk-caspy inflammasome signaling in vivo. Fish & Shellfish Immunol. 2019;[Epub ahead of print] doi:10.1016/j.fsi.2019.05.051.

Specific miRNA-GPCR networks regulate Sox9a/Sox9b activities to promote gonadal rejuvenation in zebrafish

Authors:
Guo H, Du X, Zhang Y, Wu J, Wang C, Li M, Hua X, Zhang XA, Yan J
Citation:
Stem Cells. 2019 May 22. doi: 10.1002/stem.3040. [Epub ahead of print]
Epub:
Yes
Abstract:
Fertility and endocrine function rely on a tightly regulated synchronicity within the hypothalamic-pituitary gonadal (HPG) axis...
Link:
https://stemcellsjournals.onlinelibrary.wiley.com/doi/abs/10.1002/stem.3040
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Guo H, Du X, Zhang Y, Wu J, Wang C, Li M, Hua X, Zhang XA, Yan J. Specific miRNA-GPCR networks regulate Sox9a/Sox9b activities to promote gonadal rejuvenation in zebrafish. Stem Cells. 2019 May 22. doi: 10.1002/stem.3040. [Epub ahead of print].

Loss of abcd4 in zebrafish leads to vitamin B12-deficiency anemia

Authors:
Choi YM, Kim YI, Choi JH, Bhandari S, Nam IK, Hong K, Kwak S, So HS, Park DS, Kim CH, Choi TY, Choe SK
Citation:
Biochem Biophys Res Commun. 2019 May 18. pii: S0006-291X(19)30979-9. doi: 10.1016/j.bbrc.2019.05.099. [Epub ahead of print]
Epub:
Yes
Abstract:
ABCD4, a member of the ATP-binding cassette transporter superfamily, is associated with the transport of vitamin B12 which is...
Link:
https://www.sciencedirect.com/science/article/pii/S0006291X19309799
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Choi YM, Kim YI, Choi JH, Bhandari S, Nam IK, Hong K, Kwak S, So HS, Park DS, Kim CH, Choi TY, Choe SK. Loss of abcd4 in zebrafish leads to vitamin B12-deficiency anemia. Biochem Biophys Res Commun. 2019 May 18. pii: S0006-291X(19)30979-9. doi: 10.1016/j.bbrc.2019.05.099. [Epub ahead of print].

Japanese Encephalitis Virus-induced let-7a/b interacted with the NOTCH-TLR7 pathway in microglia and facilitated neuronal death via caspase activation

Authors:
Mukherjee S, Akbar I, Kumari B, Vrati S, Basu A, Banerjee A
Citation:
J Neurochem. 2019 May;149(4):518-534. doi: 10.1111/jnc.14645. Epub 2019 Jan 31. PMID: 30556910
Epub:
Yes
Abstract:
MicroRNAs (miRNAs) released from the activated microglia upon neurotropic virus infection may exacerbate the neuronal damage....
Link:
https://onlinelibrary.wiley.com/doi/epdf/10.1111/jnc.14645
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice (brain)
Citation Extract:
Mukherjee S, Akbar I, Kumari B, Vrati S, Basu A, Banerjee A. Japanese Encephalitis Virus-induced let-7a/b interacted with the NOTCH-TLR7 pathway in microglia and facilitated neuronal death via caspase activation. J Neurochem. 2019 May;149(4):518-534. doi: 10.1111/jnc.14645. Epub 2019 Jan 31. PMID: 30556910.

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