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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Essential role of prostaglandin E2 and the EP3 receptor in lymphatic vessel development during zebrafish embryogenesis
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Citation:
Sci Rep. 2019;9(1):7650 doi:10.1038/s41598-019-44095-5 Epub:
Not Epub Abstract:
Lymphatic endothelial cells arise from the venous endothelial cells in embryonic lymphatic development. However, the molecular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Iwasaki R, Tsuge K, Kishimoto K, Hayashi Y, Iwaana T, Hohjoh H, Inazumi T, Kawahara A, Tsuchiya S, Sugimoto Y. Essential role of prostaglandin E2 and the EP3 receptor in lymphatic vessel development during zebrafish embryogenesis. Sci Rep. 2019;9(1):7650 doi:10.1038/s41598-019-44095-5. |
Genome-Wide Association Study-Driven Gene-Set Analyses, Genetic, and Functional Follow-Up Suggest GLIS1 as a Susceptibility Gene for Mitral Valve Prolapse
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Citation:
Circ Genom Precis Med. 2019 May;12(5):e002497. doi: 10.1161/CIRCGEN.119.002497 Epub:
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Background: Mitral valve prolapse (MVP) is a common heart valve disease, the most frequent indication for valve repair or... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yu M, Georges A, Tucker NR, Kyryachenko S, Toomer K, Schott JJ, Delling FN, Fernandez-Friera L, Solis J, Ellinor PT, Levine RA, Slaugenhaupt SA, Hagège AA, Dina C, Jeunemaitre X, Milan DJ, Norris RA, Bouatia-Naji N. Genome-Wide Association Study-Driven Gene-Set Analyses, Genetic, and Functional Follow-Up Suggest GLIS1 as a Susceptibility Gene for Mitral Valve Prolapse. Circ Genom Precis Med. 2019 May;12(5):e002497. doi: 10.1161/CIRCGEN.119.002497. |
The Innate Immune Response of Frog Embryos to Antisense Morpholino Oligomers Depends on Developmental Stage, GC Content and Dose
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Citation:
Dev Cell. 2019;49(4):506-7. doi:10.1016/j.devcel.2019.05.004 Epub:
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In this issue of Developmental Cell, Paraiso and colleagues report that antisense morpholino oligomers (MOs), frequently used... Organism or Cell Type:
Xenopus Citation Extract: Gentsch GE, Spruce T, Owens NDL, Monteiro RS, Smith JC. The Innate Immune Response of Frog Embryos to Antisense Morpholino Oligomers Depends on Developmental Stage, GC Content and Dose. Dev Cell. 2019;49(4):506-7. doi:10.1016/j.devcel.2019.05.004. |
Morpholinos Do Not Elicit an Innate Immune Response during Early Xenopus Embryogenesis
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Citation:
Dev Cell. 2019;49(4):643-50. doi:10.1016/j.devcel.2019.04.019 Epub:
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It has recently been reported that a common side effect of translation-blocking morpholino antisense oligonucleotides is the... Organism or Cell Type:
Xenopus Citation Extract: Paraiso KD, Blitz IL, Zhou JJ, Cho KWY. Morpholinos Do Not Elicit an Innate Immune Response during Early Xenopus Embryogenesis. Dev Cell. 2019;49(4):643-50. doi:10.1016/j.devcel.2019.04.019. |
Combined antisense knockdown of type 1 and type 2 iodothyronine deiodinases disrupts embryonic development in zebrafish (Danio rerio)
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Citation:
Gen Comp Endocrinol. 2010 Mar 1;166(1):134-41. doi: 10.1016/j.ygcen.2009.09.011. Epub 2009 Oct 1 Epub:
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Thyroid hormones (THs) are important regulators of gene expression during vertebrate development. In teleosts, early embryos... Organism or Cell Type:
zebrafish Citation Extract: Walpita CN, Crawford AD, Darras VM. Combined antisense knockdown of type 1 and type 2 iodothyronine deiodinases disrupts embryonic development in zebrafish (Danio rerio). Gen Comp Endocrinol. 2010 Mar 1;166(1):134-41. doi: 10.1016/j.ygcen.2009.09.011. Epub 2009 Oct 1. |
EGFR is required for Wnt9a–Fzd9b signalling specificity in haematopoietic stem cells
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Citation:
Nat Cell Biol. 2019;[Ebut ahead of print] doi:10.1038/s41556-019-0330-5 Epub:
Yes Abstract:
Wnt signalling drives many processes in development, homeostasis and disease; however, the role and mechanism of individual... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon CH, Wozniak JM, Barahona R, Kamei CN, Houston J, Carrillo-Terrazas M, Drummond IA, Gonzalez D, Willert K, Traver D. EGFR is required for Wnt9a–Fzd9b signalling specificity in haematopoietic stem cells. Nat Cell Biol. 2019;[Ebut ahead of print] doi:10.1038/s41556-019-0330-5. |
Cul4a promotes zebrafish primitive erythropoiesis via upregulating scl and gata1 expression
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Citation:
Cell Death Dis. 2019;10(6):388. doi:10.1038/s41419-019-1629-7 Epub:
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CUL4A and CUL4B are closely related members in Cullin family and can each assemble a Cullin-RING E3 ligase complex (Cullin-RING... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang F, Hu H, Liu Y, Shao M, Shao C, Gong Y. Cul4a promotes zebrafish primitive erythropoiesis via upregulating scl and gata1 expression. Cell Death Dis. 2019;10(6):388. doi:10.1038/s41419-019-1629-7. |
CiliaCarta: An integrated and validated compendium of ciliary genes
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Citation:
PLoS ONE. 2019;14(5):e0216705. doi:10.1371/journal.pone.0216705 Epub:
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The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wide range of genetic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: van Dam TJP, Kennedy J, van der Lee R, de Vrieze E, Wunderlich KA, Rix S, Dougherty GW, Lambacher NJ, Li C, Jensen VL, Leroux MR, Hjeij R, Horn N, Texier Y, Wissinger Y, van Reeuwijk J, Wheway G, Knapp B, Scheel JF, Franco B, Mans DA, van Wijk E, Képès F, Slaats GG, Toedt G, Kremer H, Omran H, Szymanska K, Koutroumpas K, Ueffing M, Nguyen T-MT, Letteboer SJF, Oud MM, van Beersum SEC, Schmidts M, Beales PL, Lu Q, Giles RH, Szklarczyk R, Russell RB, Gibson TJ, Johnson CA, Blacque OE, Wolfrum U, Boldt K, Roepman R, Hernandez-Hernandez V, Huynen MA. CiliaCarta: An integrated and validated compendium of ciliary genes. PLoS ONE. 2019;14(5):e0216705. doi:10.1371/journal.pone.0216705. |
Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis
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Citation:
J Clin Invest. 2019 May 16;130. pii: 98890. doi: 10.1172/JCI98890 Epub:
Yes Abstract:
About 1% of all newborns are affected by congenital heart disease (CHD). Recent findings identify aberrantly functioning cilia... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Burkhalter MD, Sridhar A, Sampaio P, Jacinto R, Burczyk MS, Donow C, Angenendt M, Investigators CNFCHD, Hempel M, Walther P, Pennekamp P, Omran H, Lopes SS, Ware SM, Philipp M. Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis. J Clin Invest. 2019 May 16;130. pii: 98890. doi: 10.1172/JCI98890. |
Heterogeneity across the dorso-ventral axis in zebrafish EVL is regulated by a novel module consisting of sox, snail1a and max genes
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Citation:
Mech Dev. 2012 Mar-Jun;129(1-4):13-23. doi: 10.1016/j.mod.2012.03.003. Epub 2012 Apr 12 Epub:
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In vertebrates, the dorso-ventral (DV) axis is defined by the combinatorial action of localised Wnt, FGF and Nodal signalling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen YY, Harris MP, Levesque MP, Nüsslein-Volhard C, Sonawane M. Heterogeneity across the dorso-ventral axis in zebrafish EVL is regulated by a novel module consisting of sox, snail1a and max genes. Mech Dev. 2012 Mar-Jun;129(1-4):13-23. doi: 10.1016/j.mod.2012.03.003. Epub 2012 Apr 12. |