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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Mannose Phosphate Isomerase and Mannose Regulate Hepatic Stellate Cell Activation and Fibrosis in Zebrafish and Humans
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Citation:
Hepatology. 2019 Dec;70(6):2107-2122. doi: 10.1002/hep.30677. Epub 2019 May 24. PMID: 31016744; PMCID: PMC6812593 Epub:
Not Epub Abstract:
The growing burden of liver fibrosis and lack of effective antifibrotic therapies highlight the need for identification of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: DeRossi C, Bambino K, Morrison J, Sakarin I, Villacorta-Martin C, Zhang C, Ellis JL, Fiel MI, Ybanez M, Lee YA, Huang KL, Yin C, Sakaguchi TF, Friedman SL, Villanueva A, Chu J. Mannose Phosphate Isomerase and Mannose Regulate Hepatic Stellate Cell Activation and Fibrosis in Zebrafish and Humans. Hepatology. 2019 Dec;70(6):2107-2122. doi: 10.1002/hep.30677. Epub 2019 May 24. PMID: 31016744; PMCID: PMC6812593. |
AP endonuclease 1 (Apex1) influences brain development linking oxidative stress and DNA repair
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Citation:
Cell Death Dis. 2019:10(5):348. doi:10.1038/s41419-019-1578-1 Epub:
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Brain and neurons are particularly sensitive to reactive oxygen species (ROS). Oxidative damage from ROS results in increased 8... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pei D-S, Jia P-P, Luo J-J, Liu W, Strauss PR
. AP endonuclease 1 (Apex1) influences brain development linking oxidative stress and DNA repair. Cell Death Dis. 2019:10(5):348. doi:10.1038/s41419-019-1578-1. |
penner/lgl2 is required for the integrity of the photoreceptor layer in the zebrafish retina
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Citation:
Bio Open. 2019;8:bio041830 doi:10.1242/bio.041830 Epub:
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The vertebrate retina is a complex tissue built from multiple neuronal cell types, which develop from a pseudostratified... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kujawski S, Sonawane M, Knust E. penner/lgl2 is required for the integrity of the photoreceptor layer in the zebrafish retina. Bio Open. 2019;8:bio041830 doi:10.1242/bio.041830. |
Synthesis of Nucleobase-Functionalized Morpholino Monomers
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Citation:
Methods Mol Biol. 2019;1973:107-130. doi: 10.1007/978-1-4939-9216-4_7 Epub:
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Morpholino antisense oligonucleotides are used as routine tools in developmental biology to investigate gene function during... Citation Extract: Nandi B, Pattanayak S, Paul S, Kundu J, Sinha S. Synthesis of Nucleobase-Functionalized Morpholino Monomers. Methods Mol Biol. 2019;1973:107-130. doi: 10.1007/978-1-4939-9216-4_7. |
Oligonucleotide-directed STAT3 alternative splicing switch drives anti-tumorigenic outcomes in MCF10 human breast cancer cells
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Citation:
Biochem Biophys Res Commun. 2019 Apr 19. pii: S0006-291X(19)30682-5. doi: 10.1016/j.bbrc.2019.04.054. [Epub ahead of print] Epub:
Yes Abstract:
Signal transducer and activator of transcription 3 (STAT3), a transcription factor responsive to the activation of cytokine... Organism or Cell Type:
cell culture: human MCF10CA1h Citation Extract: Tano V, Jans DA, Bogoyevitch MA. Oligonucleotide-directed STAT3 alternative splicing switch drives anti-tumorigenic outcomes in MCF10 human breast cancer cells. Biochem Biophys Res Commun. 2019 Apr 19. pii: S0006-291X(19)30682-5. doi: 10.1016/j.bbrc.2019.04.054. [Epub ahead of print]. |
Manipulation of Gene Function in Mexican Cavefish
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Citation:
J Vis Exp. 2019;146:e59093, doi:10.3791/59093 Epub:
Not Epub Abstract:
Cave animals provide a compelling system for investigating the evolutionary mechanisms and genetic bases underlying changes in... Delivery Method:
microinjection Organism or Cell Type:
Astyanax mexicanus (Mexican cavefish) Citation Extract: Stahl BA, Jaggard JB, Chin JS, Kowalko JE, Keene AC, Duboué ER. Manipulation of Gene Function in Mexican Cavefish. J Vis Exp. 2019;146:e59093, doi:10.3791/59093. |
Prostaglandin signaling regulates renal multiciliated cell specification and maturation
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Citation:
Proc Natl Acad Sci U S A. 2019 Apr 4. pii: 201813492. doi: 10.1073/pnas.1813492116. [Epub ahead of print] Epub:
Yes Abstract:
Multiciliated cells (MCCs) are specialized epithelia with apical bundles of motile cilia that direct fluid flow. MCC... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Marra AN, Adeeb BD, Chambers BE, Drummond BE, Ulrich M, Addiego A, Springer M, Poureetezadi SJ, Chambers JM, Ronshaugen M, Wingert RA. Prostaglandin signaling regulates renal multiciliated cell specification and maturation. Proc Natl Acad Sci U S A. 2019 Apr 4. pii: 201813492. doi: 10.1073/pnas.1813492116. [Epub ahead of print]. |
Neural crest streaming as an emergent property of tissue interactions during morphogenesis
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Citation:
PLoS Comput Biol. 2019;15(4):e1007002. doi:10.1371/journal.pcbi.1007002 Epub:
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A fundamental question in embryo morphogenesis is how a complex pattern is established in seemingly uniform tissues. During... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Szabó A, Theveneau E, Turan M, Mayor R. Neural crest streaming as an emergent property of tissue interactions during morphogenesis. PLoS Comput Biol. 2019;15(4):e1007002. doi:10.1371/journal.pcbi.1007002. |
Primary cilia regulate hematopoietic stem and progenitor cell specification through Notch signaling in zebrafish
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Citation:
Nat Comm. 2019;10(1):1839. doi:10.1038/s41467-019-09403-7 Epub:
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Hematopoietic stem and progenitor cells (HSPCs) are capable of producing all mature blood lineages, as well as maintaining the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu Z, Tu H, Kang Y, Xue Y, Ma D, Zhao C, Li H, Wang L, Liu F. Primary cilia regulate hematopoietic stem and progenitor cell specification through Notch signaling in zebrafish. Nat Comm. 2019;10(1):1839. doi:10.1038/s41467-019-09403-7. |
Iroquois transcription factor irx2a is required for multiciliated and transporter cell fate decisions during zebrafish pronephros development
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Citation:
Sci Rep. 2019;9(1):6454. doi:10.1038/s41598-019-42943-y Epub:
Not Epub Abstract:
The genetic regulation of nephron patterning during kidney organogenesis remains poorly understood. Nephron tubules in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Marra AN, Cheng CN, Adeeb B, Addiego A, Wesselman HM, Chambers BE, Chambers JM, Wingert RA. Iroquois transcription factor irx2a is required for multiciliated and transporter cell fate decisions during zebrafish pronephros development. Sci Rep. 2019;9(1):6454. doi:10.1038/s41598-019-42943-y. |