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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Wolf-Hirschhorn Syndrome-Associated Genes Are Enriched in Motile Neural Crest Cells and Affect Craniofacial Development in Xenopus laevis
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Citation:
Front Physiol. 2019;10:431 doi:10.3389/fphys.2019.00431 Epub:
Not Epub Abstract:
Wolf-Hirschhorn Syndrome (WHS) is a human developmental disorder arising from a hemizygous perturbation, typically a... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Mills A, Bearce E, Cella R, Kim SW, Selig M, Lee S, Lowery LA. Wolf-Hirschhorn Syndrome-Associated Genes Are Enriched in Motile Neural Crest Cells and Affect Craniofacial Development in Xenopus laevis. Front Physiol. 2019;10:431 doi:10.3389/fphys.2019.00431. |
Mutations in the zebrafish hmgcs1 gene reveal a novel function for isoprenoids during red blood cell development
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Citation:
Blood Adv. 2019;3:1244-54. doi:10.1182/bloodadvances.2018024539 Epub:
Not Epub Abstract:
Erythropoiesis is the process by which new red blood cells (RBCs) are formed and defects in this process can lead to anemia or... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hernandez JA, Castro VL, Reyes-Nava N, Montes LP, Quintana AM. Mutations in the zebrafish hmgcs1 gene reveal a novel function for isoprenoids during red blood cell development. Blood Adv. 2019;3:1244-54. doi:10.1182/bloodadvances.2018024539. |
Morphology and genome of a snailfish from the Mariana Trench provide insights into deep-sea adaptation
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Citation:
Nature Ecol Evol. 2019;[Epub ahead of print] doi:10.1038/s41559-019-0864-8 Epub:
Yes Abstract:
It is largely unknown how living organisms - especially vertebrates - survive and thrive in the coldness, darkness and high... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang K, Shen Y, Yang Y, Gan X, Liu G, Hu K, Li Y, Gao Z, Zhu L, Yan G, He L, Shan X, Yang L, Lu S, Zeng H, Pan X, Liu C, Yuan Y, Feng C, Xu W, Zhu C, Xiao W, Dong Y, Wang W, Qiu Q, He S. Morphology and genome of a snailfish from the Mariana Trench provide insights into deep-sea adaptation. Nature Ecol Evol. 2019;[Epub ahead of print] doi:10.1038/s41559-019-0864-8. |
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia
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Citation:
Exp Eye Res. 2019;[Epub ahead of print] doi:10.1016/j.exer.2019.03.024 Epub:
Yes Abstract:
During an ENU (N-ethyl-N-nitrosourea) mutagenesis screen, we observed a dominant small-eye mutant mouse with viable homozygotes... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Vetrivel S, Tiso N, Kügler A, Irmler M, Horsch M, Beckers J, Hladik D, Giesert F, Gailus-Durner V, Fuchs H, Sabrautzki S, German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health GmbH, Adler T, Treise I, Busch DH, Aguilar-Pimentel A, Ollert M, Götz A, Amarie OV, Stoeger T, Schulz H, Becker L, Klopstock T, Schrewe A, Spielmann N, Bekeredjian R, Garrett L, Hölter SM, Zimprich A, Wurst W, Mayer-Kuckuk P, Hans W, Rozman J, Klingenspor M, Neff F, da Silva-Buttkus P, Calzada-Wack J, Rácz I, Zimmer A, Rathkolb B, Wolf E, Prehn C, Adamski J, Östereicher M, Miller G, Steinkamp R, Lengger C, Maier H, Stoeger C, Leuchtenberger S, Gailus-Durner V, Fuchs H, de Angelis MH, Graw J. Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia. Exp Eye Res. 2019;[Epub ahead of print] doi:10.1016/j.exer.2019.03.024. |
Genetic mosaics and time-lapse imaging identify functions of histone H3.3 residues in mouse oocytes and embryos
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Citation:
Development. 2017 Feb 1;144(3):519-528. doi: 10.1242/dev.141390. Epub 2016 Dec 19 Epub:
Not Epub Abstract:
During development from oocyte to embryo, genetic programs in mouse germ cells are reshaped by chromatin remodeling to... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Zhou L, Baibakov B, Canagarajah B, Xiong B, Dean J. Genetic mosaics and time-lapse imaging identify functions of histone H3.3 residues in mouse oocytes and embryos. Development. 2017 Feb 1;144(3):519-528. doi: 10.1242/dev.141390. Epub 2016 Dec 19. |
Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis
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Citation:
Dev Dyn. 2019 Apr 13. doi: 10.1002/dvdy.39. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: Kabuki syndrome is a haploinsufficient congenital multi-organ malformation syndrome, which frequently includes... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Schwenty-Lara J, Nürnberger A, Borchers A. Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis. Dev Dyn. 2019 Apr 13. doi: 10.1002/dvdy.39. [Epub ahead of print]. |
The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/583807 Epub:
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Understanding how complex organ systems are assembled from simple embryonic tissues is a major challenge. Across the animal... Delivery Method:
Endo-Porter PEG Organism or Cell Type:
cell culture: Gallus gallus (chick) somite tissue Citation Extract: Grocott T, Lozano-Velasco E, Mok GF, Münsterberg AE. The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network. bioRxiv. 2019;[preprint] doi:10.1101/583807. |
Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/570820 Epub:
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Coordinated migration of cell collectives is important during embryonic development and relies on cells integrating multiple... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wei L, Blader P, Roussigné M. Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration. bioRxiv. 2019;[preprint] doi:10.1101/570820. |
Developmentally regulated tcf7l2 splice variants mediate transcriptional repressor functions during eye formation
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/607713 Epub:
Not Epub Abstract:
Tcf7l2 mediates Wnt/β-Catenin signalling during development and is implicated in cancer and type-2 diabetes. The mechanisms by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Young RM, Ewan KB, Ferrer VP, Allende ML, Dale TC, Wilson SW. Developmentally regulated tcf7l2 splice variants mediate transcriptional repressor functions during eye formation. bioRxiv. 2019;[preprint] doi:10.1101/607713 . |
miR‐181a/b downregulation exerts a protective action on mitochondrial disease models
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Citation:
EMBO Molec Med. 2019;e8734 [Epub ahead of print] doi:10.15252/emmm.201708734 Epub:
Yes Abstract:
Mitochondrial diseases (MDs) are a heterogeneous group of devastating and often fatal disorders due to defective oxidative... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Indrieri A, Carrella S, Romano A, Spaziano A, Marrocco E, Fernandez‐Vizarra E, Barbato S, Pizzo M, Ezhova Y, Golia FM, Ciampi L, Tammaro R, Henao‐Mejia J, Williams A, Flavell RA, De Leonibus E, Zeviani M, Surace EM, Banfi S, Franco B. miR‐181a/b downregulation exerts a protective action on mitochondrial disease models. EMBO Molec Med. 2019;e8734 [Epub ahead of print] doi:10.15252/emmm.201708734. |