You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Inhibition of Neogenin Promotes Neuronal Survival and Improved Behavior Recovery after Spinal Cord Injury

Authors:
Chen J, Shifman MI
Citation:
Neuroscience. 2019;[Epub ahead of print] doi:10.1016/j.neuroscience.2019.03.055
Epub:
Yes
Abstract:
Following spinal cord trauma, axonal regeneration in the mammalian spinal cord do not occur and functional recovery may be...
Organism or Cell Type:
lamprey
Citation Extract:
Chen J, Shifman MI. Inhibition of Neogenin Promotes Neuronal Survival and Improved Behavior Recovery after Spinal Cord Injury. Neuroscience. 2019;[Epub ahead of print] doi:10.1016/j.neuroscience.2019.03.055.

Time Space Translation: A Confirmed Primary Axial Patterning Mechanism in Vertebrates

Authors:
Durston AJ
Citation:
Preprints. 2019:2019030262 [preprint]
Epub:
Not Epub
Abstract:
The vertebrate anterior-posterior (A-P) body axis arises due to time space translation (TST). BMP dependent Hox temporal...
Organism or Cell Type:
Xenopus
Citation Extract:
Durston AJ. Time Space Translation: A Confirmed Primary Axial Patterning Mechanism in Vertebrates. Preprints. 2019:2019030262 [preprint] .

A U2-snRNP-independent role of SF3b in promoting mRNA export

Authors:
Wang K, Yin C, Du X, Chen S, Wang J, Zhang L, Wang L, Yu Y, Chi B, Shi M, Wang C, Reed R, Zhou Y, Huang J, Cheng H
Citation:
Proc Natl Acad Sci USA. 2019;116(16):7837-46. doi:10.1073/pnas.1818835116
Epub:
Not Epub
Abstract:
To ensure efficient and accurate gene expression, pre-mRNA processing and mRNA export need to be balanced. However, how this...
Delivery Method:
microinjection
Organism or Cell Type:
cell culture
Citation Extract:
Wang K, Yin C, Du X, Chen S, Wang J, Zhang L, Wang L, Yu Y, Chi B, Shi M, Wang C, Reed R, Zhou Y, Huang J, Cheng H. A U2-snRNP-independent role of SF3b in promoting mRNA export. Proc Natl Acad Sci USA. 2019;116(16):7837-46. doi:10.1073/pnas.1818835116 .

Latrophilin2 is involved in neural crest cell migration and placode patterning in Xenopus laevis

Authors:
Yokote N, Suzuki-Kosaka MY, Michiue T, Hara T, Tanegashima K
Citation:
Int J Dev Biol. 2019;63(1-2):29-35. doi: 10.1387/ijdb.180184kt
Epub:
Not Epub
Abstract:
Latrophilin2 (Lphn2) is an adhesion-class of G protein-coupled receptor with an unknown function in development. Here, we show...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yokote N, Suzuki-Kosaka MY, Michiue T, Hara T, Tanegashima K. Latrophilin2 is involved in neural crest cell migration and placode patterning in Xenopus laevis. Int J Dev Biol. 2019;63(1-2):29-35. doi: 10.1387/ijdb.180184kt.

Loss of PKC mu function induces cytoskeletal defects in mouse oocyte meiosis

Authors:
Zhang Y, Wu LL, Wan X, Wang HH, Li XH, Pan ZN, Sun SC
Citation:
J Cell Physiol. 2019 Mar 25. doi: 10.1002/jcp.28487. [Epub ahead of print]
Epub:
Yes
Abstract:
Cytoskeleton which includes microtubule and actin filaments plays important roles during mammalian oocyte maturation. In the...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Zhang Y, Wu LL, Wan X, Wang HH, Li XH, Pan ZN, Sun SC. Loss of PKC mu function induces cytoskeletal defects in mouse oocyte meiosis. J Cell Physiol. 2019 Mar 25. doi: 10.1002/jcp.28487. [Epub ahead of print].

Epigenetic inactivation of miR-203 as a key step in neural crest epithelial-to-mesenchymal transition

Authors:
Sánchez-Vásquez E, Bronner ME, Strobl-Mazzulla PH
Citation:
Development. 2019;[Epub ahead of print] doi:10.1242/dev.171017
Epub:
Yes
Abstract:
miR-203 is a tumor-suppressor microRNA with known functions in cancer metastasis. Here, we explore its normal developmental...
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Sánchez-Vásquez E, Bronner ME, Strobl-Mazzulla PH. Epigenetic inactivation of miR-203 as a key step in neural crest epithelial-to-mesenchymal transition. Development. 2019;[Epub ahead of print] doi:10.1242/dev.171017.

A threonyl-tRNA synthetase-mediated translation initiation machinery

Authors:
Jeong SJ, Park S, Nguyen LT, Hwang J, Lee E-Y, Giong H-K, Lee J-S, Yoon I, Lee J-H, Kim JH, Kim HK, Kim D, Yang WS, Kim S-Y, Lee CY, Yu K, Sonenberg N, Kim MH, Kim S
Citation:
Nat Comm. 2019;10:1357. doi:10.1038/s41467-019-09086-0
Epub:
Not Epub
Abstract:
A fundamental question in biology is how vertebrates evolved and differ from invertebrates, and little is known about...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jeong SJ, Park S, Nguyen LT, Hwang J, Lee E-Y, Giong H-K, Lee J-S, Yoon I, Lee J-H, Kim JH, Kim HK, Kim D, Yang WS, Kim S-Y, Lee CY, Yu K, Sonenberg N, Kim MH, Kim S. A threonyl-tRNA synthetase-mediated translation initiation machinery. Nat Comm. 2019;10:1357. doi:10.1038/s41467-019-09086-0.

A recurrent COL6A1 pseudoexon insertion causes muscular dystrophy and is effectively targeted by splice-correction therapies

Authors:
Bolduc V, Foley AR, Solomon-Degefa H, Sarathy A, Donkervoort S, Hu Y, Chen GS, Sizov K, Nalls M, Zhou H, Aguti S, Cummings BB, Lek M, Tukiainen T, Marshall JL, Regev O, Marek-Yagel D, Sarkozy A, Butterfield RJ, Jou C, Jimenez-Mallebrera C, Li Y, Gartioux C, Mamchaoui K, Allamand V, Gualandi F, Ferlini A, Hanssen E; COL6A1 Intron 11 Study Group, Wilton SD, Lamandé SR, MacArthur DG, Wagener R, Muntoni F, Bönnemann CG
Citation:
JCI Insight. 2019 Mar 21;4(6). pii: 124403. doi: 10.1172/jci.insight.124403. eCollection 2019 Mar 21
Epub:
Not Epub
Abstract:
The clinical application of advanced next-generation sequencing technologies is increasingly uncovering novel classes of...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human dermal fibroblasts, HEK293T
Citation Extract:
Bolduc V, Foley AR, Solomon-Degefa H, Sarathy A, Donkervoort S, Hu Y, Chen GS, Sizov K, Nalls M, Zhou H, Aguti S, Cummings BB, Lek M, Tukiainen T, Marshall JL, Regev O, Marek-Yagel D, Sarkozy A, Butterfield RJ, Jou C, Jimenez-Mallebrera C, Li Y, Gartioux C, Mamchaoui K, Allamand V, Gualandi F, Ferlini A, Hanssen E; COL6A1 Intron 11 Study Group, Wilton SD, Lamandé SR, MacArthur DG, Wagener R, Muntoni F, Bönnemann CG. A recurrent COL6A1 pseudoexon insertion causes muscular dystrophy and is effectively targeted by splice-correction therapies. JCI Insight. 2019 Mar 21;4(6). pii: 124403. doi: 10.1172/jci.insight.124403. eCollection 2019 Mar 21.

Moderate Nucleoporin 133 deficiency leads to glomerular damage in zebrafish

Authors:
Cianciolo Cosentino C, Berto A, Pelletier S, Hari M, Loffing J, Neuhauss SCF, Doye V
Citation:
Sci Rep. 2019 Mar 18;9(1):4750. doi: 10.1038/s41598-019-41202-4
Epub:
Not Epub
Abstract:
Although structural nuclear pore proteins (nucleoporins) are seemingly required in every cell type to assemble a functional...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cianciolo Cosentino C, Berto A, Pelletier S, Hari M, Loffing J, Neuhauss SCF, Doye V. Moderate Nucleoporin 133 deficiency leads to glomerular damage in zebrafish. Sci Rep. 2019 Mar 18;9(1):4750. doi: 10.1038/s41598-019-41202-4.

Genome-wide identification of alternative splicing events that regulate protein transport across the secretory pathway

Authors:
Neumann A, Schindler M, Olofsson D, Wilhelmi I, Schürmann A, Heyd F
Citation:
J Cell Sci. 2019 Mar 19. pii: jcs.230201. doi: 10.1242/jcs.230201. [Epub ahead of print]
Epub:
Yes
Abstract:
Alternative splicing (AS) strongly increases proteome diversity and functionality in eukaryotic cells. Protein secretion is a...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture:HEK293T
Citation Extract:
Neumann A, Schindler M, Olofsson D, Wilhelmi I, Schürmann A, Heyd F. Genome-wide identification of alternative splicing events that regulate protein transport across the secretory pathway. J Cell Sci. 2019 Mar 19. pii: jcs.230201. doi: 10.1242/jcs.230201. [Epub ahead of print].

Pages