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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12092 scientific papers returned from the database with the search filters currently being used below.

Zebrafish M(2) muscarinic acetylcholine receptor: cloning, pharmacological characterization, expression patterns and roles in embryonic bradycardia

Authors:
Hsieh DJ, Liao CF
Citation:
Br J Pharmacol. 2002 Nov 6;137(6):782-792
Epub:
Not Epub
Abstract:
1. A zebrafish M(2) muscarinic acetylcholine receptor (mAChR) gene was cloned. It encodes 495 amino acids in a single exon. The...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hsieh DJ, Liao CF. Zebrafish M(2) muscarinic acetylcholine receptor: cloning, pharmacological characterization, expression patterns and roles in embryonic bradycardia. Br J Pharmacol. 2002 Nov 6;137(6):782-792.

Zebrafish Mef2ca and Mef2cb are essential for both first and second heart field cardiomyocyte differentiation

Authors:
Hinits Y, Pan L, Walker C, Dowd J, Moens CB, Hughes SM
Citation:
Dev Biol. 2012 Jun 28. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Mef2 transcription factors have been strongly linked with early heart development. D-mef2 is required for heart formation in...
Organism or Cell Type:
zebrafish
Citation Extract:
Hinits Y, Pan L, Walker C, Dowd J, Moens CB, Hughes SM. Zebrafish Mef2ca and Mef2cb are essential for both first and second heart field cardiomyocyte differentiation. Dev Biol. 2012 Jun 28. [Epub ahead of print].

Zebrafish models for ectopic mineralization disorders: practical issues from morpholino design to post-injection observations

Authors:
Hosen MJ, Vanakker OM, Willaert A, Huysseune A, Coucke P, De Paepe A
Citation:
Frontiers Genet. 2013;74 doi:10.3389/fgene.2013.00074
Epub:
Not Epub
Abstract:
Zebrafish (ZF, Danio rerio) has emerged as an important and popular model species to study different human diseases. Key...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hosen MJ, Vanakker OM, Willaert A, Huysseune A, Coucke P, De Paepe A. Zebrafish models for ectopic mineralization disorders: practical issues from morpholino design to post-injection observations. Frontiers Genet. 2013;74 doi:10.3389/fgene.2013.00074.

Zebrafish relatively relaxed mutants have a ryanodine receptor defect, show slow swimming and provide a model of multi-minicore disease

Authors:
Hirata H, Watanabe T, Hatakeyama J, Sprague SM, Saint-Amant L, Nagashima A, Cui WW, Zhou W, Kuwada JY
Citation:
Development. 2007 Aug;134(15):2771-81. Epub 2007 Jun 27
Epub:
Not Epub
Abstract:
Wild-type zebrafish embryos swim away in response to tactile stimulation. By contrast, relatively relaxed mutants swim slowly...
Organism or Cell Type:
zebrafish
Citation Extract:
Hirata H, Watanabe T, Hatakeyama J, Sprague SM, Saint-Amant L, Nagashima A, Cui WW, Zhou W, Kuwada JY. Zebrafish relatively relaxed mutants have a ryanodine receptor defect, show slow swimming and provide a model of multi-minicore disease. Development. 2007 Aug;134(15):2771-81. Epub 2007 Jun 27.

[Impaired effect of BHC80 gene knock-down on the cardiac development in zebrafish]

Authors:
Hou J-Y, Song DL, Jin D-Q, Hu JY, Wang X-D
Citation:
Acta Physiol Sinica. 2013;(65)5:[Epub ahead of print][Article in Chinese]
Epub:
Not Epub
Abstract:
The effect of BHC80 ( BRAF35-HDAC complex protein BHC80 ) on development was not well studied, because BHC80 gene knock-out...
Link:
http://www.actaps.com.cn/qikan/manage/wenzhang/2013-5-11.pdf
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hou J-Y, Song DL, Jin D-Q, Hu JY, Wang X-D. [Impaired effect of BHC80 gene knock-down on the cardiac development in zebrafish]. Acta Physiol Sinica. 2013;(65)5:[Epub ahead of print][Article in Chinese].

A comparison of in vitro and in vivo stability in mice of two morpholino duplexes differing in chain length.

Authors:
He J, Liu G, Zhang S, Vanderheyden JL, Liu N, Liu C, Zhang Y, Gupta S, Rusckowski M, Hnatowich DJ
Citation:
Bioconjug Chem. 2003 Sep-Oct;14(5):1018-23
Epub:
Not Epub
Abstract:
The stability of hybridized duplexes is an important criterion for any radiopharmaceutical application of DNAs or their...
Delivery Method:
in vivo: injection
Organism or Cell Type:
male CD-1 mice
Citation Extract:
He J, Liu G, Zhang S, Vanderheyden JL, Liu N, Liu C, Zhang Y, Gupta S, Rusckowski M, Hnatowich DJ. A comparison of in vitro and in vivo stability in mice of two morpholino duplexes differing in chain length.. Bioconjug Chem. 2003 Sep-Oct;14(5):1018-23.

A Gap Junction Connexin Is Required In The Vertebrate Left-Right Organizer

Authors:
Hatler JM, Essner JJ, Johnson RG
Citation:
Dev Biol. 2009 Sep 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Early patterning of vertebrate embryos involves the generation of asymmetric signals across the left-right (L-R) axis that...
Organism or Cell Type:
zebrafish
Citation Extract:
Hatler JM, Essner JJ, Johnson RG. A Gap Junction Connexin Is Required In The Vertebrate Left-Right Organizer. Dev Biol. 2009 Sep 29. [Epub ahead of print].

A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon

Authors:
Heisenberg CP, Houart C, Take-Uchi M, Rauch GJ, Young N, Coutinho P, Masai I, Caneparo L, Concha ML, Geisler R, Dale TC, Wilson SW, Stemple DL
Citation:
Genes Dev. 2001 Jun 1;15(11):1427-34
Epub:
Not Epub
Abstract:
Zebrafish embryos homozygous for the masterblind (mbl) mutation exhibit a striking phenotype in which the eyes and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Heisenberg CP, Houart C, Take-Uchi M, Rauch GJ, Young N, Coutinho P, Masai I, Caneparo L, Concha ML, Geisler R, Dale TC, Wilson SW, Stemple DL. A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon. Genes Dev. 2001 Jun 1;15(11):1427-34.

A role for Tbx5 in proepicardial cell migration during cardiogenesis

Authors:
Hatcher CJ, Diman NY, Kim MS, Pennisi D, Song Y, Goldstein MM, Mikawa T, Basson CT
Citation:
Physiol Genomics. 2004 Jul 8;18(2):129-40
Epub:
Not Epub
Abstract:
Transcriptional regulatory cascades during epicardial and coronary vascular development from proepicardial progenitor cells...
Delivery Method:
Special Delivery
Organism or Cell Type:
organ culture: chick proepicardial organ explant
Citation Extract:
Hatcher CJ, Diman NY, Kim MS, Pennisi D, Song Y, Goldstein MM, Mikawa T, Basson CT. A role for Tbx5 in proepicardial cell migration during cardiogenesis. Physiol Genomics. 2004 Jul 8;18(2):129-40.

A sensitive and reproducible assay to measure the activity of glucosylceramide synthase and lactosylceramide synthase using HPLC and fluorescent substrates

Authors:
Hayashi Y, Horibata Y, Sakaguchi K, Okino N, Ito M
Citation:
Anal Biochem. 2005 Oct 15;345(2):181-6. Epub 2005 Jun 13.
Epub:
Not Epub
Abstract:
Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hayashi Y, Horibata Y, Sakaguchi K, Okino N, Ito M. A sensitive and reproducible assay to measure the activity of glucosylceramide synthase and lactosylceramide synthase using HPLC and fluorescent substrates. Anal Biochem. 2005 Oct 15;345(2):181-6. Epub 2005 Jun 13..

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