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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12092 scientific papers returned from the database with the search filters currently being used below.

Determination of Endothelial Stalk versus Tip Cell Potential during Angiogenesis by H2.0-like Homeobox-1

Authors:
Herbert SP, Cheung JY, Stainier DY
Citation:
Curr Biol. 2012 Oct 9;22(19):1789-94. doi: 10.1016/j.cub.2012.07.037. Epub 2012 Aug 23
Epub:
Not Epub
Abstract:
Tissue branching morphogenesis requires the hierarchical organization of sprouting cells into leading \"tip\" and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Herbert SP, Cheung JY, Stainier DY. Determination of Endothelial Stalk versus Tip Cell Potential during Angiogenesis by H2.0-like Homeobox-1. Curr Biol. 2012 Oct 9;22(19):1789-94. doi: 10.1016/j.cub.2012.07.037. Epub 2012 Aug 23.

Development of an efficient method for phosphorodiamidate bond formation by using inorganic salts

Authors:
Harakawa T, Tsunoda H, Ohkubo A, Seio K, Sekine M
Citation:
Bioorg Med Chem Lett. 2011;[Epub ahead of print] doi:10.1016/j.bmcl.2011.12.021
Epub:
Not Epub
Abstract:
Phosphorodiamidate morpholino oligonucleotides (PMOs) have been extensively applied in antisense strategies for gene regulation...
Citation Extract:
Harakawa T, Tsunoda H, Ohkubo A, Seio K, Sekine M. Development of an efficient method for phosphorodiamidate bond formation by using inorganic salts. Bioorg Med Chem Lett. 2011;[Epub ahead of print] doi:10.1016/j.bmcl.2011.12.021.

Differential Role of PTEN Phosphatase in Chemotactic Growth Cone Guidance

Authors:
Henle SJ, Carlstrom LP, Cheever TR, Henley JR
Citation:
J Biol Chem. 2013 Jun 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Negatively targeting the tumor suppressor and phosphoinositide phosphatase PTEN promotes axon re-growth after injury. How PTEN...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Henle SJ, Carlstrom LP, Cheever TR, Henley JR. Differential Role of PTEN Phosphatase in Chemotactic Growth Cone Guidance. J Biol Chem. 2013 Jun 17. [Epub ahead of print].

Disruption of Esrom and Ryk identifies the roof plate boundary as an intermediate target for commissure formation

Authors:
Hendricks M, Mathuru AS, Wang H, Silander O, Kee MZ, Jesuthasan S
Citation:
Mol Cell Neurosci. 2008 Feb;37(2):271-83. Epub 2007 Oct 16.
Epub:
Not Epub
Abstract:
Growth cones are guided to their final destination by intermediate targets. Here, we identify intermediate targets and...
Organism or Cell Type:
zebrafish
Citation Extract:
Hendricks M, Mathuru AS, Wang H, Silander O, Kee MZ, Jesuthasan S. Disruption of Esrom and Ryk identifies the roof plate boundary as an intermediate target for commissure formation. Mol Cell Neurosci. 2008 Feb;37(2):271-83. Epub 2007 Oct 16..

Eif4a3 is required for accurate splicing of the Xenopus laevis ryanodine receptor pre-mRNA

Authors:
Haremaki T, Weinstein DC
Citation:
Dev Biol. 2012;[Epub ahead of print]
Epub:
Not Epub
Abstract:
The Exon Junction Complex (EJC) plays a critical role in multiple posttranscriptional events, including RNA subcellular l...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Haremaki T, Weinstein DC. Eif4a3 is required for accurate splicing of the Xenopus laevis ryanodine receptor pre-mRNA. Dev Biol. 2012;[Epub ahead of print] .

Eye and neural defects associated with loss of GDF6

Authors:
Hanel ML, Hensey C
Citation:
BMC Dev Biol. 2006 Sep 29;6:43.
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: In Xenopus the bone morphogenetic protein growth and differentiation factor 6 (GDF6) is expressed at the...
Organism or Cell Type:
Xenopus
Citation Extract:
Hanel ML, Hensey C. Eye and neural defects associated with loss of GDF6. BMC Dev Biol. 2006 Sep 29;6:43..

Fgf-dependent otic induction requires competence provided by Foxi1 and Dlx3b

Authors:
Hans S, Christison J, Liu D, Westerfield M
Citation:
BMC Dev Biol. 2007 Jan 19;7:5
Epub:
Not Epub
Abstract:
BACKGROUND: The inner ear arises from a specialized set of cells, the otic placode, that forms at the lateral edge of the...
Organism or Cell Type:
zebrafish
Citation Extract:
Hans S, Christison J, Liu D, Westerfield M. Fgf-dependent otic induction requires competence provided by Foxi1 and Dlx3b. BMC Dev Biol. 2007 Jan 19;7:5.

Generation and Characterization of a zebrafish model of SMA carrying the human SMN2 gene

Authors:
Hao LT, Burghes AHM, Beattie CE
Citation:
Molecular Neurodegeneration 2011, 6:24 doi:10.1186/1750-1326-6-24
Epub:
Not Epub
Abstract:
Animal models of human diseases are essential as they allow analysis of the disease process at the cellular level and can...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hao LT, Burghes AHM, Beattie CE. Generation and Characterization of a zebrafish model of SMA carrying the human SMN2 gene. Molecular Neurodegeneration 2011, 6:24 doi:10.1186/1750-1326-6-24.

Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development

Authors:
Hartwig S, Ho J, Pandey P, Macisaac K, Taglienti M, Xiang M, Alterovitz G, Ramoni M, Fraenkel E, Kreidberg JA
Citation:
Development. 2010 Apr;137(7):1189-203
Epub:
Not Epub
Abstract:
The Wilms' tumor suppressor 1 (WT1) gene encodes a DNA- and RNA-binding protein that plays an essential role in nephron...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Mouse kidney explants, embryonic
Citation Extract:
Hartwig S, Ho J, Pandey P, Macisaac K, Taglienti M, Xiang M, Alterovitz G, Ramoni M, Fraenkel E, Kreidberg JA. Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development. Development. 2010 Apr;137(7):1189-203.

Glucose metabolism impacts the spatio-temporal onset and magnitude of HSC induction in vivo

Authors:
Harris JM, Esain V, Frechette GM, Harris LJ, Cox AG, Cortes M, Garnaas MK, Carroll KJ, Cutting CC, Khan T, Elks PM, Renshaw SA, Dickinson BC, Chang CJ, Murphy MP, Paw BH, Heiden MGV, Goessling W, North TE
Citation:
Blood. 2012;[Epub ahead of print] doi:10.1182/blood-2012-12-471201
Epub:
Not Epub
Abstract:
Many pathways regulating blood formation have been elucidated, yet how each coordinates with embryonic biophysiology to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Harris JM, Esain V, Frechette GM, Harris LJ, Cox AG, Cortes M, Garnaas MK, Carroll KJ, Cutting CC, Khan T, Elks PM, Renshaw SA, Dickinson BC, Chang CJ, Murphy MP, Paw BH, Heiden MGV, Goessling W, North TE. Glucose metabolism impacts the spatio-temporal onset and magnitude of HSC induction in vivo. Blood. 2012;[Epub ahead of print] doi:10.1182/blood-2012-12-471201.

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