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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12092 scientific papers returned from the database with the search filters currently being used below.

Kremen is required for neural crest induction in Xenopus and promotes LRP6-mediated Wnt signaling

Authors:
Hassler C, Cruciat CM, Huang YL, Kuriyama S, Mayor R, Niehrs C
Citation:
Development. 2007 Dec;134(23):4255-63. Epub 2007 Oct 31
Epub:
Not Epub
Abstract:
Kremen 1 and 2 (Krm1/2) are transmembrane receptors for Wnt antagonists of the Dickkopf (Dkk) family and function by inhibiting...
Organism or Cell Type:
Xenopus
Citation Extract:
Hassler C, Cruciat CM, Huang YL, Kuriyama S, Mayor R, Niehrs C. Kremen is required for neural crest induction in Xenopus and promotes LRP6-mediated Wnt signaling. Development. 2007 Dec;134(23):4255-63. Epub 2007 Oct 31.

Lengsin expression and function during zebrafish lens formation

Authors:
Harding RL, Howley S, Baker LJ, Murphy TR, Archer WE, Wistow G, Hyde DR, Vihtelic TS
Citation:
Exp Eye Res. 2008 May;86(5):807-18. Epub 2008 Mar 2.
Epub:
Not Epub
Abstract:
A zebrafish ortholog of human lengsin was identified by EST analysis of an adult lens cDNA library. During zebrafish...
Organism or Cell Type:
zebrafish
Citation Extract:
Harding RL, Howley S, Baker LJ, Murphy TR, Archer WE, Wistow G, Hyde DR, Vihtelic TS. Lengsin expression and function during zebrafish lens formation. Exp Eye Res. 2008 May;86(5):807-18. Epub 2008 Mar 2..

miR-10 Regulates the Angiogenic Behavior of Zebrafish and Human Endothelial Cells by Promoting VEGF Signaling

Authors:
Hassel D, Cheng P, White MP, Ivey KN, Kroll J, Augustin HG, Katus HA, Stainier DY, Srivastava D
Citation:
Circ Res. 2012 Sep 5. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Rationale: Formation and remodeling of the vasculature during development and disease involves a highly conserved and precisely...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hassel D, Cheng P, White MP, Ivey KN, Kroll J, Augustin HG, Katus HA, Stainier DY, Srivastava D. miR-10 Regulates the Angiogenic Behavior of Zebrafish and Human Endothelial Cells by Promoting VEGF Signaling. Circ Res. 2012 Sep 5. [Epub ahead of print].

miR-196 regulates axial patterning and pectoral appendage initiation

Authors:
He X, Yan YL, Eberhart JK, Herpin A, Wagner TU, Schartl M, Postlethwait JH
Citation:
Dev Biol. 2011 Jul 20. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Vertebrate Hox clusters contain protein-coding genes that regulate body axis development and microRNA (miRNA) genes whose...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
He X, Yan YL, Eberhart JK, Herpin A, Wagner TU, Schartl M, Postlethwait JH. miR-196 regulates axial patterning and pectoral appendage initiation. Dev Biol. 2011 Jul 20. [Epub ahead of print].

Molecular biology of flaviviruses

Authors:
Harris E, Holden KL, Edgil D, Polacek C, Clyde K
Citation:
Novartis Found Symp. 2006;277:23-39; discussion 40, 71-3, 251-3
Epub:
Not Epub
Abstract:
Flaviviruses are enveloped viruses with a single-stranded, 10.7kb positive-sense RNA genome. The genomic RNA, which has a 5...
Delivery Method:
peptide-coupled
Citation Extract:
Harris E, Holden KL, Edgil D, Polacek C, Clyde K. Molecular biology of flaviviruses. Novartis Found Symp. 2006;277:23-39; discussion 40, 71-3, 251-3.

Morpholino Oligo Antisense efficiently suppresses BCR/ABL and cell proliferation in CML: specific inhibition of BCR-ABL gene expression by Morpholino Oligo Antisense in BCR-ABL(+) cells

Authors:
Haririan M, Kaviani S, Soleimani M, Ghaemi SR, Delalat B, Atashi A
Citation:
Hematology. 2012 Jan;17(1):28-34
Epub:
Not Epub
Abstract:
Chronic myeloid leukemia is a disorder that develops when a hematopoietic stem cell acquires the Philadelphia chromosome...
Organism or Cell Type:
cell culture: human K562
Citation Extract:
Haririan M, Kaviani S, Soleimani M, Ghaemi SR, Delalat B, Atashi A. Morpholino Oligo Antisense efficiently suppresses BCR/ABL and cell proliferation in CML: specific inhibition of BCR-ABL gene expression by Morpholino Oligo Antisense in BCR-ABL(+) cells. Hematology. 2012 Jan;17(1):28-34.

Morpholino oligonucleotide knockdown of the extracellular calcium-sensing receptor impairs early skeletal development in zebrafish

Authors:
Herberger AL, Loretz CA
Citation:
Comp Biochem Physiol A Mol Integr Physiol. 2013 Aug 1. doi:pii: S1095-6433(13)00205-5. 10.1016/j.cbpa.2013.07.027. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The complex vertebrate skeleton depends on regulated cell activities to lay down protein matrix and mineral components of bone...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Herberger AL, Loretz CA. Morpholino oligonucleotide knockdown of the extracellular calcium-sensing receptor impairs early skeletal development in zebrafish. Comp Biochem Physiol A Mol Integr Physiol. 2013 Aug 1. doi:pii: S1095-6433(13)00205-5. 10.1016/j.cbpa.2013.07.027. [Epub ahead of print].

Morpholino oligos: making sense of antisense?

Authors:
Heasman J
Citation:
Dev Biol. 2002 Mar 15;243(2):209-14
Epub:
Not Epub
Abstract:
Since morpholino oligos were first introduced as a means to inhibit gene function in embryos, in the Spring of 2000, they have...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Heasman J. Morpholino oligos: making sense of antisense?. Dev Biol. 2002 Mar 15;243(2):209-14.

Muscular dystrophy candidate gene FRG1 is critical for muscle development

Authors:
Hanel ML, Wuebbles RD, Jones PL
Citation:
Dev Dyn. 2008 Dec 18. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The leading candidate gene responsible for facioscapulohumeral muscular dystrophy (FSHD) is FRG1 (FSHD region gene 1). However...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hanel ML, Wuebbles RD, Jones PL. Muscular dystrophy candidate gene FRG1 is critical for muscle development. Dev Dyn. 2008 Dec 18. [Epub ahead of print].

Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model

Authors:
He S, Lamers GE, Beenakker JW, Cui C, Ghotra VP, Danen EH, Meijer AH, Spaink HP, Snaar-Jagalska BE
Citation:
J Pathol. 2012 Aug;227(4):431-45. doi: 10.1002/path.4013. Epub 2012 Jul 3
Epub:
Not Epub
Abstract:
Inhibition of VEGF signalling effectively suppresses localized tumour growth but accelerates tumour invasiveness and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
He S, Lamers GE, Beenakker JW, Cui C, Ghotra VP, Danen EH, Meijer AH, Spaink HP, Snaar-Jagalska BE. Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model. J Pathol. 2012 Aug;227(4):431-45. doi: 10.1002/path.4013. Epub 2012 Jul 3.

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