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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
Targeted knock-down of a structurally atypical zebrafish 12S-lipoxygenase leads to severe impairment of embryonic development
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Citation:
Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20479-84. Epub 2011 Dec 5 Epub:
Not Epub Abstract:
Lipoxygenases (LO) are a class of dioxygenases, which form hydroperoxy, hydroxy, and epoxy derivatives of arachidonic acid with... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Haas U, Raschperger E, Hamberg M, Samuelsson B, Tryggvason K, Haeggström JZ. Targeted knock-down of a structurally atypical zebrafish 12S-lipoxygenase leads to severe impairment of embryonic development. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20479-84. Epub 2011 Dec 5. |
Tbx2b is essential for neuronal differentiation along the dorsal/ventral axis of the zebrafish retina
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Citation:
Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4371-6. Epub 2005 Mar 8 Epub:
Not Epub Abstract:
The mechanisms by which retinal neurons are patterned along the dorsal/ventral axis remain largely unknown, yet this patterning... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Gross JM, Dowling JE. Tbx2b is essential for neuronal differentiation along the dorsal/ventral axis of the zebrafish retina. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4371-6. Epub 2005 Mar 8. |
Tcf3 inhibits spinal cord neurogenesis by regulating sox4a expression
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Citation:
Development. 2009 Mar;136(5):781-9. Epub 2009 Jan 28 Epub:
Not Epub Abstract:
The Lef/Tcf factor Tcf3 is expressed throughout the developing vertebrate central nervous system (CNS), but its function and... Organism or Cell Type:
zebrafish Citation Extract: Gribble SL, Kim HS, Bonner J, Wang X, Dorsky RI. Tcf3 inhibits spinal cord neurogenesis by regulating sox4a expression. Development. 2009 Mar;136(5):781-9. Epub 2009 Jan 28. |
The 8-oxoguanine DNA glycosylase 1 (ogg1) decreases the vulnerability of the developing brain to DNA damage
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Citation:
DNA Repair (Amst). 2013 Sep 25. doi:pii: S1568-7864(13)00230-9. 10.1016/j.dnarep.2013.08.018. [Epub ahead of print] Epub:
Not Epub Abstract:
The developing brain is particularly vulnerable to oxidative DNA damage, which may be the cause of most major congenital mental... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Gu A, Ji G, Yan L, Zhou Y. The 8-oxoguanine DNA glycosylase 1 (ogg1) decreases the vulnerability of the developing brain to DNA damage. DNA Repair (Amst). 2013 Sep 25. doi:pii: S1568-7864(13)00230-9. 10.1016/j.dnarep.2013.08.018. [Epub ahead of print]. |
The Dependence Receptor UNC5H2/B Triggers Apoptosis via PP2A-Mediated Dephosphorylation of DAP Kinas
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Citation:
Mol Cell. 2010 Dec 22;40(6):863-76 Epub:
Not Epub Abstract:
The UNC5H dependence receptors promote apoptosis in the absence of their ligand, netrin-1, and this is important for neuronal... Delivery Method:
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zebrafish Citation Extract: Guenebeaud C, Goldschneider D, Castets M, Guix C, Chazot G, Delloye-Bourgeois C, Eisenberg-Lerner A, Shohat G, Zhang M, Laudet V, Kimchi A, Bernet A, Mehlen P. The Dependence Receptor UNC5H2/B Triggers Apoptosis via PP2A-Mediated Dephosphorylation of DAP Kinas. Mol Cell. 2010 Dec 22;40(6):863-76. |
The developing lamprey ear closely resembles the zebrafish otic vesicle: otx1 expression can account for all major patterning differences
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Citation:
Development. 2006 Apr;133(7):1347-57. Epub 2006 Mar 1 Epub:
Not Epub Abstract:
The inner ear of adult agnathan vertebrates is relatively symmetric about the anteroposterior axis, with only two semicircular... Delivery Method:
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Petromyzon marinus (sea lamprey) Citation Extract: Hammond KL, Whitfield TT. The developing lamprey ear closely resembles the zebrafish otic vesicle: otx1 expression can account for all major patterning differences. Development. 2006 Apr;133(7):1347-57. Epub 2006 Mar 1. |
The dystrophin associated protein complex in zebrafish
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Citation:
Hum Mol Genet 2003 Mar 15;12(6):601-15 Epub:
Not Epub Abstract:
Many cases of muscular dystrophy in humans are caused by mutations in members of the dystrophin associated protein complex (... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Guyon JR, Mosley AN, Zhou Y, O'Brien KF, Sheng X, Chiang K, Davidson AJ, Volinski JM, Zon LI, Kunkel LM. The dystrophin associated protein complex in zebrafish. Hum Mol Genet 2003 Mar 15;12(6):601-15. |
The INT6 Cancer Gene and MEK Signaling Pathways Converge during Zebrafish Development
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Citation:
PLoS ONE. 2007 Sep 26;2(9):e959 Epub:
Not Epub Abstract:
BACKGROUND: Int-6 (integration site 6) was identified as an oncogene in a screen of tumorigenic mouse mammary tumor virus (MMTV... Organism or Cell Type:
zebrafish Citation Extract: Grzmil M, Whiting D, Maule J, Anastasaki C, Amatruda JF, Kelsh RN, Norbury CJ, Patton EE. The INT6 Cancer Gene and MEK Signaling Pathways Converge during Zebrafish Development. PLoS ONE. 2007 Sep 26;2(9):e959. |
The lmx1b gene is pivotal in glomus development in Xenopus laevis
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Citation:
Dev Biol. 2008 Jul 21. [Epub ahead of print] Epub:
Not Epub Abstract:
We have previously shown that lmx1b, a LIM homeodomain protein, is expressed in the pronephric glomus. We now show temporal and... Organism or Cell Type:
Xenopus laevis Citation Extract: Haldin CE, Massé KL, Bhamra S, Simrick S, Kyuno JI, Jones EA. The lmx1b gene is pivotal in glomus development in Xenopus laevis. Dev Biol. 2008 Jul 21. [Epub ahead of print]. |
The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity
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Citation:
J Clin Invest. 2007 Dec;117(12):3940-51 Epub:
Not Epub Abstract:
Statins inhibit HMG-CoA reductase, a key enzyme in cholesterol synthesis, and are widely used to treat hypercholesterolemia.... Delivery Method:
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zebrafish Citation Extract: Hanai J, Cao P, Tanksale P, Imamura S, Koshimizu E, Zhao J, Kishi S, Yamashita M, Phillips PS, Sukhatme VP, Lecker SH. The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity. J Clin Invest. 2007 Dec;117(12):3940-51. |