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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

An essential role for Radar (Gdf6a) in inducing dorsal fate in the zebrafish retina

Authors:
Gosse NJ, Baier H
Citation:
Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2236-41. Epub 2009 Jan 21
Epub:
Not Epub
Abstract:
Retinal ganglion cells form orderly topographic connections with the tectum, establishing a continuous neural representation of...
Organism or Cell Type:
zebrafish
Citation Extract:
Gosse NJ, Baier H. An essential role for Radar (Gdf6a) in inducing dorsal fate in the zebrafish retina. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2236-41. Epub 2009 Jan 21.

atp2b1a regulates Ca(2+) export during differentiation and regeneration of mechanosensory hair cells in zebrafish

Authors:
Go W, Bessarab D, Korzh V
Citation:
Cell Calcium. 2010 Nov 15. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The molecular mechanisms of development of mechanosensory hair cells have been tackled successfully due to in vivo studies in...
Organism or Cell Type:
zebrafish
Citation Extract:
Go W, Bessarab D, Korzh V. atp2b1a regulates Ca(2+) export during differentiation and regeneration of mechanosensory hair cells in zebrafish. Cell Calcium. 2010 Nov 15. [Epub ahead of print].

CC2D2A is mutated in Joubert syndrome and interacts with the ciliopathy-associated basal body protein CEP290

Authors:
Gorden NT, Arts HH, Parisi MA, Coene KL, Letteboer SJ, van Beersum SE, Mans DA, Hikida A, Eckert M, Knutzen D, Alswaid AF, Ozyurek H, Dibooglu S, Otto EA, Liu Y, Davis EE, Hutter CM, Bammler TK, Farin FM, Dorschner M, Topçu M, Zackai EH, Rosenthal P, Owens KN, Katsanis N, Vincent JB, Hildebrandt F, Rubel EW, Raible DW, Knoers NV, Chance PF, Roepman R, Moens CB, Glass IA, Doherty D
Citation:
Am J Hum Genet. 2008 Nov;83(5):559-71. Epub 2008 Oct 23
Epub:
Not Epub
Abstract:
Joubert syndrome and related disorders (JSRD) are primarily autosomal-recessive conditions characterized by hypotonia, ataxia,...
Organism or Cell Type:
zebrafish
Citation Extract:
Gorden NT, Arts HH, Parisi MA, Coene KL, Letteboer SJ, van Beersum SE, Mans DA, Hikida A, Eckert M, Knutzen D, Alswaid AF, Ozyurek H, Dibooglu S, Otto EA, Liu Y, Davis EE, Hutter CM, Bammler TK, Farin FM, Dorschner M, Topçu M, Zackai EH, Rosenthal P, Owens KN, Katsanis N, Vincent JB, Hildebrandt F, Rubel EW, Raible DW, Knoers NV, Chance PF, Roepman R, Moens CB, Glass IA, Doherty D . CC2D2A is mutated in Joubert syndrome and interacts with the ciliopathy-associated basal body protein CEP290. Am J Hum Genet. 2008 Nov;83(5):559-71. Epub 2008 Oct 23.

Challenges to oligonucleotides-based therapeutics for Duchenne muscular dystrophy

Authors:
Goyenvalle A, Davies KE
Citation:
Skeletal Muscle. 2011;1:8 doi:10.1186/2044-5040-1-8
Epub:
Not Epub
Abstract:
Antisense oligonucleotides are short nucleic acids designed to bind to specific messenger RNAs in order to modulate splicing...
Citation Extract:
Goyenvalle A, Davies KE. Challenges to oligonucleotides-based therapeutics for Duchenne muscular dystrophy. Skeletal Muscle. 2011;1:8 doi:10.1186/2044-5040-1-8.

Characterization of DrCol15a1b, a Novel Component of the Stem-Cell Niche in the Zebrafish Retina

Authors:
Gonzalez-Nunez V, Nocco V, Budd A
Citation:
Stem Cells. 2010 Jun 14. [Epub ahead of print]
Epub:
Not Epub
Abstract:
There is a clear need to develop novel tools to help improve our understanding of stem-cell biology, and potentially also the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gonzalez-Nunez V, Nocco V, Budd A. Characterization of DrCol15a1b, a Novel Component of the Stem-Cell Niche in the Zebrafish Retina. Stem Cells. 2010 Jun 14. [Epub ahead of print].

Chemokine ligand Xenopus CXCLC (XCXCLC) regulates cell movements during early morphogenesis

Authors:
Goto T, Asashima M
Citation:
Dev Growth Differ. 2011 Nov 22. doi: 10.1111/j.1440-169X.2011.01304.x. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We cloned the gene for the CXC-type chemokine ligand, Xenopus CXCLC (XCXCLC), the transcripts of which were detected at the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Goto T, Asashima M. Chemokine ligand Xenopus CXCLC (XCXCLC) regulates cell movements during early morphogenesis. Dev Growth Differ. 2011 Nov 22. doi: 10.1111/j.1440-169X.2011.01304.x. [Epub ahead of print].

Combinatorial interaction between CCM pathway genes precipitates hemorrhagic stroke

Authors:
Gore AV, Lampugnani MG, Dye L, Dejana E, Weinstein BM
Citation:
Dis Model Mech. 2008 Nov-Dec;1(4-5):275-81. Epub 2008 Oct 28
Epub:
Not Epub
Abstract:
Intracranial hemorrhage (ICH) is a particularly severe form of stroke whose etiology remains poorly understood, with a highly...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gore AV, Lampugnani MG, Dye L, Dejana E, Weinstein BM. Combinatorial interaction between CCM pathway genes precipitates hemorrhagic stroke. Dis Model Mech. 2008 Nov-Dec;1(4-5):275-81. Epub 2008 Oct 28.

Cytochrome P450 1D1: A novel CYP1A-related gene that is not transcriptionally activated by PCB126 or TCDD

Authors:
Goldstone JV, Jönsson ME, Behrendt L, Woodin BR, Jenny MJ, Nelson DR, Stegeman JJ
Citation:
Arch Biochem Biophys. 2008 Dec 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Enzymes in the cytochrome P450 1 family oxidize many common environmental toxicants. We identified a new CYP1, termed CYP1D1,...
Organism or Cell Type:
zebrafish
Citation Extract:
Goldstone JV, Jönsson ME, Behrendt L, Woodin BR, Jenny MJ, Nelson DR, Stegeman JJ. Cytochrome P450 1D1: A novel CYP1A-related gene that is not transcriptionally activated by PCB126 or TCDD. Arch Biochem Biophys. 2008 Dec 10. [Epub ahead of print].

Def6 Is Required for Convergent Extension Movements during Zebrafish Gastrulation Downstream of Wnt5b Signaling

Authors:
Goudevenou K, Martin P, Yeh Y-J, Jones P, Sablitzky F
Citation:
PLoS ONE. 2011;6(10):e26548. doi:10.1371/journal.pone.0026548
Epub:
Not Epub
Abstract:
During gastrulation, convergent extension (CE) cell movements are regulated through the non-canonical Wnt signaling pathway....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Goudevenou K, Martin P, Yeh Y-J, Jones P, Sablitzky F. Def6 Is Required for Convergent Extension Movements during Zebrafish Gastrulation Downstream of Wnt5b Signaling. PLoS ONE. 2011;6(10):e26548. doi:10.1371/journal.pone.0026548.

Design and analysis of effects of triplet repeat oligonucleotides in cell models for myotonic dystrophy

Authors:
González-Barriga A, Mulders SA, van de Giessen J, Hooijer JD, Bijl S, van Kessel ID, van Beers J, van Deutekom JC, Fransen JA, Wieringa B, Wansink DG
Citation:
Mol Ther Nucleic Acids. 2013 Mar 19;2:e81. doi: 10.1038/mtna.2013.9
Epub:
Not Epub
Abstract:
Myotonic dystrophy type 1 (DM1) is caused by DM protein kinase (DMPK) transcripts containing an expanded (CUG)n repeat....
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: mouse immortalized DM500 myoblasts differentiated to myotubes
Citation Extract:
González-Barriga A, Mulders SA, van de Giessen J, Hooijer JD, Bijl S, van Kessel ID, van Beers J, van Deutekom JC, Fransen JA, Wieringa B, Wansink DG. Design and analysis of effects of triplet repeat oligonucleotides in cell models for myotonic dystrophy. Mol Ther Nucleic Acids. 2013 Mar 19;2:e81. doi: 10.1038/mtna.2013.9.

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