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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12067 scientific papers returned from the database with the search filters currently being used below.

De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia

Authors:
Gauthier J, Champagne N, Lafrenière RG, Xiong L, Spiegelman D, Brustein E, Lapointe M, Peng H, Côté M, Noreau A, Hamdan FF, Addington AM, Rapoport JL, Delisi LE, Krebs MO, Joober R, Fathalli F, Mouaffak F, Haghighi AP, Néri C, Dubé MP, Samuels ME, Marineau C, Stone EA, Awadalla P, Barker PA, Carbonetto S, Drapeau P, Rouleau GA; the S2D Team
Citation:
Proc Natl Acad Sci U S A. 2010 Apr 12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Schizophrenia likely results from poorly understood genetic and environmental factors. We studied the gene encoding the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gauthier J, Champagne N, Lafrenière RG, Xiong L, Spiegelman D, Brustein E, Lapointe M, Peng H, Côté M, Noreau A, Hamdan FF, Addington AM, Rapoport JL, Delisi LE, Krebs MO, Joober R, Fathalli F, Mouaffak F, Haghighi AP, Néri C, Dubé MP, Samuels ME, Marineau C, Stone EA, Awadalla P, Barker PA, Carbonetto S, Drapeau P, Rouleau GA; the S2D Team. De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia . Proc Natl Acad Sci U S A. 2010 Apr 12. [Epub ahead of print].

Developmental time rather than local environment regulates the schedule of epithelial polarization in the zebrafish neural rod

Authors:
Girdler GC, Araya C, Ren X, Clarke JD
Citation:
Neural Dev. 2013 Mar 24;8:5. doi: 10.1186/1749-8104-8-5
Epub:
Not Epub
Abstract:
Background Morphogenesis requires developmental processes to occur both at the right time and in the right place. During neural...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Girdler GC, Araya C, Ren X, Clarke JD. Developmental time rather than local environment regulates the schedule of epithelial polarization in the zebrafish neural rod. Neural Dev. 2013 Mar 24;8:5. doi: 10.1186/1749-8104-8-5.

Direct role of Bardet-Biedl syndrome proteins in transcriptional regulation

Authors:
Gascue C, Tan PL, Cardenas-Rodriguez M, Libisch G, Fernandez-Calero T, Liu YP, Astrada S, Robello C, Naya H, Katsanis N, Badano JL
Citation:
J Cell Sci. 2012 Jan 15;125(Pt 2):362-75. doi: 10.1242/jcs.089375. Epub 2012 Feb 2
Epub:
Not Epub
Abstract:
Primary cilia are conserved organelles that play crucial roles as mechano- and chemosensors, as well as transducing signaling...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gascue C, Tan PL, Cardenas-Rodriguez M, Libisch G, Fernandez-Calero T, Liu YP, Astrada S, Robello C, Naya H, Katsanis N, Badano JL. Direct role of Bardet-Biedl syndrome proteins in transcriptional regulation. J Cell Sci. 2012 Jan 15;125(Pt 2):362-75. doi: 10.1242/jcs.089375. Epub 2012 Feb 2.

Directional asymmetry of the zebrafish epithalamus guides dorsoventral innervation of the midbrain target

Authors:
Gamse JT, Kuan YS, Macurak M, Brosamle C, Thisse B, Thisse C, Halpern ME
Citation:
Development. 2005 Nov;132(21):4869-81. Epub 2005 Oct 5
Epub:
Not Epub
Abstract:
The zebrafish epithalamus, consisting of the pineal complex and flanking dorsal habenular nuclei, provides a valuable model for...
Organism or Cell Type:
zebrafish
Citation Extract:
Gamse JT, Kuan YS, Macurak M, Brosamle C, Thisse B, Thisse C, Halpern ME. Directional asymmetry of the zebrafish epithalamus guides dorsoventral innervation of the midbrain target. Development. 2005 Nov;132(21):4869-81. Epub 2005 Oct 5.

Dissociation of cardiogenic and postnatal myocardial activities of GATA4

Authors:
Gallagher JM, Komati H, Roy E, Nemer M, Latinkić BV
Citation:
Mol Cell Biol. 2012 Jun;32(12):2214-23. Epub 2012 Apr 2
Epub:
Not Epub
Abstract:
Transcription factor GATA4 is a critical regulator of the embryonic and postnatal heart, but the mechanisms and cofactors...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Gallagher JM, Komati H, Roy E, Nemer M, Latinkić BV. Dissociation of cardiogenic and postnatal myocardial activities of GATA4. Mol Cell Biol. 2012 Jun;32(12):2214-23. Epub 2012 Apr 2.

Distinct phenotypes in zebrafish models of human startle disease

Authors:
Ganser LR, Yan Q, James VM, Kozol R, Topf M, Harvey RJ, Dallman JE
Citation:
Neurobiol Dis. 2013 Sep 9. doi:pii: S0969-9961(13)00238-6. 10.1016/j.nbd.2013.09.002. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Startle disease is an inherited neurological disorder that causes affected individuals to suffer noise- or touch-induced non-...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ganser LR, Yan Q, James VM, Kozol R, Topf M, Harvey RJ, Dallman JE. Distinct phenotypes in zebrafish models of human startle disease. Neurobiol Dis. 2013 Sep 9. doi:pii: S0969-9961(13)00238-6. 10.1016/j.nbd.2013.09.002. [Epub ahead of print].

EDEN-BP-dependent post-transcriptional regulation of gene expression in Xenopus somitic segmentation

Authors:
Gautier-Courteille C, Le Clainche C, Barreau C, Audic Y, Graindorge A, Maniey D, Osborne HB, Paillard L
Citation:
Development. 2004 Dec;131(24):6107-17. Epub 2004 Nov 17.
Epub:
Not Epub
Abstract:
EDEN-BP is a Xenopus RNA-binding protein that triggers deadenylation [poly(A) tail shortening], and thereby translational...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Gautier-Courteille C, Le Clainche C, Barreau C, Audic Y, Graindorge A, Maniey D, Osborne HB, Paillard L. EDEN-BP-dependent post-transcriptional regulation of gene expression in Xenopus somitic segmentation. Development. 2004 Dec;131(24):6107-17. Epub 2004 Nov 17..

Embryological and genetic manipulation of chick development

Authors:
Gammill LS, Krull CE
Citation:
Methods Mol Biol. 2011;770:119-37
Epub:
Not Epub
Abstract:
The ability to combine embryological manipulations with gene function analysis makes the chick a valuable system for the...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Gammill LS, Krull CE. Embryological and genetic manipulation of chick development. Methods Mol Biol. 2011;770:119-37.

Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice

Authors:
Fu J, Gerhardt H, McDaniel JM, Xia B, Liu X, Ivanciu L, Ny A, Hermans K, Silasi-Mansat R, McGee S, Nye E, Ju T, Ramirez MI, Carmeliet P, Cummings RD, Lupu F, Xia L
Citation:
J Clin Invest. 2008 Nov;118(11):3725-37. Epub 2008 Oct 16
Epub:
Not Epub
Abstract:
Mucin-type O-glycans (O-glycans) are highly expressed in vascular ECs. However, it is not known whether they are important for...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus and zebrafish
Citation Extract:
Fu J, Gerhardt H, McDaniel JM, Xia B, Liu X, Ivanciu L, Ny A, Hermans K, Silasi-Mansat R, McGee S, Nye E, Ju T, Ramirez MI, Carmeliet P, Cummings RD, Lupu F, Xia L. Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice. J Clin Invest. 2008 Nov;118(11):3725-37. Epub 2008 Oct 16.

Essential role for fibrillin-2 in zebrafish notochord and vascular morphogenesis

Authors:
Gansner JM, Madsen EC, Mecham RP, Gitlin JD
Citation:
Dev Dyn. 2008 Sep 24;237(10):2844-2861. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Recent studies demonstrate that lysyl oxidase cuproenzymes are critical for zebrafish notochord formation, but the molecular...
Organism or Cell Type:
zebrafish
Citation Extract:
Gansner JM, Madsen EC, Mecham RP, Gitlin JD. Essential role for fibrillin-2 in zebrafish notochord and vascular morphogenesis. Dev Dyn. 2008 Sep 24;237(10):2844-2861. [Epub ahead of print].

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