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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

Antisense morpholino oligonucleotide analog induces missplicing of c-myc mRNA

Authors:
Giles RV, Spiller DG, Clark RE, Tidd DM
Citation:
Antisense Nucleic Acid Drug Dev 1999 Apr;9(2):213-20
Epub:
Not Epub
Abstract:
A 28-mer morpholino oligonucleotide analog was designed to hybridize to 8 bases of intron 1 and extend 2 bases beyond the...
Delivery Method:
streptolysin O
Organism or Cell Type:
cell culture: human leukemia lines
Citation Extract:
Giles RV, Spiller DG, Clark RE, Tidd DM. Antisense morpholino oligonucleotide analog induces missplicing of c-myc mRNA. Antisense Nucleic Acid Drug Dev 1999 Apr;9(2):213-20.

Antisense phosphorodiamidate morpholino oligomer inhibits viability of Escherichia coli in pure culture and in mouse peritonitis

Authors:
Geller BL, Deere J, Tilley L, Iversen PL
Citation:
J Antimicrob Chemother. 2005 Jun;55(6):983-8. Epub 2005 May 4.
Epub:
Not Epub
Abstract:
OBJECTIVES: Antisense phosphorodiamidate morpholino oligomers (PMOs) are synthetic DNA mimics that specifically inhibit gene...
Delivery Method:
in vivo: injection
Organism or Cell Type:
Escherichia coli
Citation Extract:
Geller BL, Deere J, Tilley L, Iversen PL. Antisense phosphorodiamidate morpholino oligomer inhibits viability of Escherichia coli in pure culture and in mouse peritonitis. J Antimicrob Chemother. 2005 Jun;55(6):983-8. Epub 2005 May 4..

ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling

Authors:
Gee HY, Saisawat P, Ashraf S, Hurd TW, Vega-Warner V, Fang H, Beck BB, Gribouval O, Zhou W, Diaz KA, Natarajan S, Wiggins RC, Lovric S, Chernin G, Schoeb DS, Ovunc B, Frishberg Y, Soliman NA, Fathy HM, Goebel H, Hoefele J, Weber LT, Innis JW, Faul C, Han Z, Washburn J, Antignac C, Levy S, Otto EA, Hildebrandt F
Citation:
J Clin Invest. 2013;[Epub ahead of print] doi:10.1172/JCI69134
Epub:
Not Epub
Abstract:
Nephrotic syndrome (NS) is divided into steroid-sensitive (SSNS) and -resistant (SRNS) variants. SRNS causes end-stage kidney...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gee HY, Saisawat P, Ashraf S, Hurd TW, Vega-Warner V, Fang H, Beck BB, Gribouval O, Zhou W, Diaz KA, Natarajan S, Wiggins RC, Lovric S, Chernin G, Schoeb DS, Ovunc B, Frishberg Y, Soliman NA, Fathy HM, Goebel H, Hoefele J, Weber LT, Innis JW, Faul C, Han Z, Washburn J, Antignac C, Levy S, Otto EA, Hildebrandt F. ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling. J Clin Invest. 2013;[Epub ahead of print] doi:10.1172/JCI69134 .

Assembly and patterning of the vascular network of the vertebrate hindbrain

Authors:
Fujita M, Cha YR, Pham VN, Sakurai A, Roman BL, Gutkind JS, Weinstein BM
Citation:
Development. 2011 May;138(9):1705-15. Epub 2011 Mar 23.
Epub:
Not Epub
Abstract:
The cranial vasculature is essential for the survival and development of the central nervous system and is important in stroke...
Organism or Cell Type:
zebrafish
Citation Extract:
Fujita M, Cha YR, Pham VN, Sakurai A, Roman BL, Gutkind JS, Weinstein BM. Assembly and patterning of the vascular network of the vertebrate hindbrain. Development. 2011 May;138(9):1705-15. Epub 2011 Mar 23..

bHLH transcription factor Her5 links patterning to regional inhibition of neurogenesis at the midbrain-hindbrain boundary

Authors:
Geling A, Itoh M, Tallafuss A, Chapouton P, Tannhauser B, Kuwada JY, Chitnis AB, Bally-Cuif L
Citation:
Development 2003 Apr 15;130(8):1591-1604
Epub:
Not Epub
Abstract:
The midbrain-hindbrain (MH) domain of the vertebrate embryonic neural plate displays a stereotypical profile of neuronal...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Geling A, Itoh M, Tallafuss A, Chapouton P, Tannhauser B, Kuwada JY, Chitnis AB, Bally-Cuif L. bHLH transcription factor Her5 links patterning to regional inhibition of neurogenesis at the midbrain-hindbrain boundary. Development 2003 Apr 15;130(8):1591-1604.

Bisphenol A induces otolith malformations during vertebrate embryogenesis

Authors:
Gibert Y, Sassi-Messai S, Fini JB, Bernard L, Zalko D, Cravedi JP, Balaguer P, Andersson-Lendahl M, Demeneix B, Laudet V
Citation:
BMC Dev Biol. 2011 Jan 26;11(1):4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: The plastic monomer and plasticizer bisphenol A (BPA), used for manufacturing polycarbonate plastic and epoxy...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gibert Y, Sassi-Messai S, Fini JB, Bernard L, Zalko D, Cravedi JP, Balaguer P, Andersson-Lendahl M, Demeneix B, Laudet V. Bisphenol A induces otolith malformations during vertebrate embryogenesis. BMC Dev Biol. 2011 Jan 26;11(1):4. [Epub ahead of print].

BMP Signaling Modulates Hepcidin Expression in Zebrafish Embryos Independent of Hemojuvelin

Authors:
Gibert Y, Lattanzi VJ, Zhen AW, Vedder L, Brunet F, Faasse SA, Babitt JL, Lin HY, Hammerschmidt M, Fraenkel PG
Citation:
PLoS ONE. 2011;6(1):e14553. doi:10.1371/journal.pone.0014553
Epub:
Not Epub
Abstract:
Hemojuvelin (Hjv), a member of the repulsive-guidance molecule (RGM) family, upregulates transcription of the iron regulatory...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gibert Y, Lattanzi VJ, Zhen AW, Vedder L, Brunet F, Faasse SA, Babitt JL, Lin HY, Hammerschmidt M, Fraenkel PG. BMP Signaling Modulates Hepcidin Expression in Zebrafish Embryos Independent of Hemojuvelin. PLoS ONE. 2011;6(1):e14553. doi:10.1371/journal.pone.0014553.

BMP, Wnt and FGF signals are integrated through evolutionarily conserved enhancers to achieve robust expression of Pax3 and Zic genes at the zebrafish neural plate border

Authors:
Garnett AT, Square TA, Medeiros DM
Citation:
Development. 2012 Oct 3. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Neural crest cells generate a range of cells and tissues in the vertebrate head and trunk, including peripheral neurons,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Garnett AT, Square TA, Medeiros DM. BMP, Wnt and FGF signals are integrated through evolutionarily conserved enhancers to achieve robust expression of Pax3 and Zic genes at the zebrafish neural plate border. Development. 2012 Oct 3. [Epub ahead of print].

Brain tumor tandem targeting using a combination of monoclonal antibodies attached to biopoly(beta-L-malic acid)

Authors:
Fujita M, Lee BS, Khazenzon NM, Penichet ML, Wawrowsky KA, Patil R, Ding H, Holler E, Black KL, Ljubimova JY
Citation:
J Control Release. 2007 Oct 8;122(3):356-63. Epub 2007 Jun 5
Epub:
Not Epub
Abstract:
Tumor-specific targeting using achievements of nanotechnology is a mainstay of increasing efficacy of anti-tumor drugs. To...
Delivery Method:
Polycefin: poly(malic acid) from Physarum polycephalum
Organism or Cell Type:
mice
Citation Extract:
Fujita M, Lee BS, Khazenzon NM, Penichet ML, Wawrowsky KA, Patil R, Ding H, Holler E, Black KL, Ljubimova JY. Brain tumor tandem targeting using a combination of monoclonal antibodies attached to biopoly(beta-L-malic acid). J Control Release. 2007 Oct 8;122(3):356-63. Epub 2007 Jun 5.

c-Flip expression and function in fetal mouse gonocytes

Authors:
Giampietri C, Petrungaro S, Klinger FG, Coluccia P, Paone A, Vivarelli E, Filippini A, De Cesaris P, De Felici M, Ziparo E
Citation:
FASEB J. 2006 Jan;20(1):124-6. Epub 2005 Nov 1
Epub:
Not Epub
Abstract:
Apoptosis is a key mechanism in spermatogenesis, and in testis, most gonocytes degenerate at fetal and postnatal ages to select...
Delivery Method:
Not Specific
Organism or Cell Type:
mouse gonocytes
Citation Extract:
Giampietri C, Petrungaro S, Klinger FG, Coluccia P, Paone A, Vivarelli E, Filippini A, De Cesaris P, De Felici M, Ziparo E. c-Flip expression and function in fetal mouse gonocytes. FASEB J. 2006 Jan;20(1):124-6. Epub 2005 Nov 1.

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