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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12092 scientific papers returned from the database with the search filters currently being used below.

Her5 acts as a prepattern factor that blocks neurogenin1 and coe2 expression upstream of Notch to inhibit neurogenesis at the midbrain-hindbrain boundary

Authors:
Geling A, Plessy C, Rastegar S, Strähle U, Bally-Cuif L
Citation:
Development. 2004 May;131(9):1993-2006. Epub 2004 Mar 31
Epub:
Not Epub
Abstract:
Neurogenesis in both vertebrates and invertebrates is tightly controlled in time and space involving both positive and negative...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Geling A, Plessy C, Rastegar S, Strähle U, Bally-Cuif L. Her5 acts as a prepattern factor that blocks neurogenin1 and coe2 expression upstream of Notch to inhibit neurogenesis at the midbrain-hindbrain boundary. Development. 2004 May;131(9):1993-2006. Epub 2004 Mar 31.

Homer regulates calcium signalling in growth cone turning

Authors:
Gasperini R, Choi-Lundberg D, Thompson MJ, Mitchell CB, Foa L
Citation:
Neural Dev. 2009 Aug 3;4:29
Epub:
Not Epub
Abstract:
BACKGROUND: Homer proteins are post-synaptic density proteins with known functions in receptor trafficking and calcium...
Delivery Method:
syringe loading
Organism or Cell Type:
Dorsal root ganglia (DRG) sensory neurons from Wistar rats
Citation Extract:
Gasperini R, Choi-Lundberg D, Thompson MJ, Mitchell CB, Foa L. Homer regulates calcium signalling in growth cone turning. Neural Dev. 2009 Aug 3;4:29.

HpSulf, a heparan sulfate 6-O-endosulfatase, is involved in the regulation of VEGF signaling during sea urchin development

Authors:
Fujita K, Takechi E, Sakamoto N, Sumiyoshi N, Izumi S, Miyamoto T, Matsuura S, Tsurugaya T, Akasaka K, Yamamoto T
Citation:
Mech Dev. 2009 Dec 24. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cell surface heparan sulfate proteoglycans (HSPGs) play significant roles in the regulation of developmental signaling,...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Hemicentrotus pulcherrimus
Citation Extract:
Fujita K, Takechi E, Sakamoto N, Sumiyoshi N, Izumi S, Miyamoto T, Matsuura S, Tsurugaya T, Akasaka K, Yamamoto T. HpSulf, a heparan sulfate 6-O-endosulfatase, is involved in the regulation of VEGF signaling during sea urchin development. Mech Dev. 2009 Dec 24. [Epub ahead of print].

Human retinopathy-associated ciliary protein Retinitis Pigmentosa GTPase Regulator (RPGR) regulates cilia-dependent vertebrate development

Authors:
Ghosh AK, Murga-Zamalloa CA, Chan L, Hitchcock PF, Swaroop A, Khanna H
Citation:
Hum Mol Genet. 2009 Oct 8. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Dysfunction of primary cilia is associated with tissue-specific or syndromic disorders. RPGR is a ciliary protein, mutations in...
Organism or Cell Type:
zebrafish
Citation Extract:
Ghosh AK, Murga-Zamalloa CA, Chan L, Hitchcock PF, Swaroop A, Khanna H. Human retinopathy-associated ciliary protein Retinitis Pigmentosa GTPase Regulator (RPGR) regulates cilia-dependent vertebrate development. Hum Mol Genet. 2009 Oct 8. [Epub ahead of print].

Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis

Authors:
Ghosh G, Subramanian IV, Adhikari N, Zhang X, Joshi HP, Basi D, Chandrashekhar YS, Hall JL, Roy S, Zeng Y, Ramakrishnan S
Citation:
J Clin Invest. 2010 Oct 25. pii: 42980. doi: 10.1172/JCI42980. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Adaptive changes to oxygen availability are critical for cell survival and tissue homeostasis. Prolonged oxygen deprivation due...
Delivery Method:
Endo-Porter
Organism or Cell Type:
Cell Culture: human umbilical vein endothelial cells (HUVECs)
Citation Extract:
Ghosh G, Subramanian IV, Adhikari N, Zhang X, Joshi HP, Basi D, Chandrashekhar YS, Hall JL, Roy S, Zeng Y, Ramakrishnan S. Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis. J Clin Invest. 2010 Oct 25. pii: 42980. doi: 10.1172/JCI42980. [Epub ahead of print].

Identification of direct T-box target genes in the developing zebrafish mesoderm

Authors:
Garnett AT, Han TM, Gilchrist MJ, Smith JC, Eisen MB, Wardle FC, Amacher SL
Citation:
Development. 2009 Mar;136(5):749-60. Epub 2009 Jan 21
Epub:
Not Epub
Abstract:
The zebrafish genes spadetail (spt) and no tail (ntl) encode T-box transcription factors that are important for early mesoderm...
Organism or Cell Type:
zebrafish
Citation Extract:
Garnett AT, Han TM, Gilchrist MJ, Smith JC, Eisen MB, Wardle FC, Amacher SL. Identification of direct T-box target genes in the developing zebrafish mesoderm. Development. 2009 Mar;136(5):749-60. Epub 2009 Jan 21.

In Vivo T-Box Transcription Factor Profiling Reveals Joint Regulation of Embryonic Neuromesodermal Bipotency

Authors:
Gentsch GE, Owens NDL, Martin SR, Piccinelli P, Faial T, Trotter MWB, Gilchrist MJ, Smith JC
Citation:
Cell Rep. 2013;[Epub ahead of print] doi:10.1016/j.celrep.2013.08.012
Epub:
Not Epub
Abstract:
The design of effective cell replacement therapies requires detailed knowledge of how embryonic stem cells form primary tissues...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Gentsch GE, Owens NDL, Martin SR, Piccinelli P, Faial T, Trotter MWB, Gilchrist MJ, Smith JC. In Vivo T-Box Transcription Factor Profiling Reveals Joint Regulation of Embryonic Neuromesodermal Bipotency. Cell Rep. 2013;[Epub ahead of print] doi:10.1016/j.celrep.2013.08.012.

Inappropriate gene activation in FSHD: a repressor complex binds a chromosomal repeat deleted in dystrophic muscle

Authors:
Gabellini D, Green MR, Tupler R
Citation:
Cell. 2002 Aug 9;110(3):339-48
Epub:
Not Epub
Abstract:
Facioscapulohumeral muscular dystrophy (FSHD), a common myopathy, is an autosomal dominant disease of unknown molecular...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: HeLa cells
Citation Extract:
Gabellini D, Green MR, Tupler R. Inappropriate gene activation in FSHD: a repressor complex binds a chromosomal repeat deleted in dystrophic muscle. Cell. 2002 Aug 9;110(3):339-48.

Inhibition of gene expression in Escherichia coli by antisense phosphorodiamidate morpholino oligomers.

Authors:
Geller BL, Deere JD, Stein DA, Kroeker AD, Moulton HM, Iversen PL.
Citation:
Antimicrob Agents Chemother. 2003 Oct;47(10):3233-9.
Epub:
Not Epub
Abstract:
Antisense phosphorodiamidate morpholino oligomers (PMOs) were tested for the ability to inhibit gene expression in Escherichia...
Delivery Method:
peptide-coupled
Organism or Cell Type:
Escherichia coli
Citation Extract:
Geller BL, Deere JD, Stein DA, Kroeker AD, Moulton HM, Iversen PL.. Inhibition of gene expression in Escherichia coli by antisense phosphorodiamidate morpholino oligomers.. Antimicrob Agents Chemother. 2003 Oct;47(10):3233-9..

Inhibition of influenza A virus production in vero cells with morpholino oligomers

Authors:
Ge Q, Stein D, Kroeker A, Iversen P, Chen J
Citation:
Program and abstracts of the 44th Interscience Conference of Antimicrobial Agents and Chemotherapy; October 30-November 2, 2004; Washington, DC. Abstract V-1268
Epub:
Not Epub
Citation Extract:
Ge Q, Stein D, Kroeker A, Iversen P, Chen J. Inhibition of influenza A virus production in vero cells with morpholino oligomers. Program and abstracts of the 44th Interscience Conference of Antimicrobial Agents and Chemotherapy; October 30-November 2, 2004; Washington, DC. Abstract V-1268.

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