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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12092 scientific papers returned from the database with the search filters currently being used below.

Inhibition of laminin-8 in vivo using a novel poly(malic acid)-based carrier reduces glioma angiogenesis

Authors:
Fujita M, Khazenzon NM, Ljubimov AV, Lee BS, Virtanen I, Holler E, Black KL, Ljubimova JY
Citation:
Angiogenesis. 2006;9(4):183-91. Epub 2006 Nov 16
Epub:
Not Epub
Abstract:
We have previously shown that laminin-8, a vascular basement membrane component, was overexpressed in human glioblastomas...
Link:
http://link.springer.com/article/10.1007%2Fs10456-006-9046-9
Delivery Method:
Polycefin: poly(malic acid) from Physarum polycephalum
Organism or Cell Type:
cell culture: glioblastoma cells,nude rats with human glioblastomas
Citation Extract:
Fujita M, Khazenzon NM, Ljubimov AV, Lee BS, Virtanen I, Holler E, Black KL, Ljubimova JY. Inhibition of laminin-8 in vivo using a novel poly(malic acid)-based carrier reduces glioma angiogenesis. Angiogenesis. 2006;9(4):183-91. Epub 2006 Nov 16.

Inhibition of Multiple Subtypes of Influenza A Virus in Cell Cultures with Morpholino Oligomers

Authors:
Ge Q, Pastey M, Kobasa D, Puthavathana P, Lupfer C, Bestwick RK, Iversen PL, Chen J, Stein DA
Citation:
Antimicrob Agents Chemother. 2006 Nov;50(11):3724-33. Epub 2006 Sep 11
Epub:
Not Epub
Abstract:
Peptide conjugated phosphorodiamidate morpholino oligomers (P-PMO) are single-stranded-nucleic-acid-like antisense agents that...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture
Citation Extract:
Ge Q, Pastey M, Kobasa D, Puthavathana P, Lupfer C, Bestwick RK, Iversen PL, Chen J, Stein DA. Inhibition of Multiple Subtypes of Influenza A Virus in Cell Cultures with Morpholino Oligomers. Antimicrob Agents Chemother. 2006 Nov;50(11):3724-33. Epub 2006 Sep 11.

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

Authors:
Fuentealba LC, Eivers E, Ikeda A, Hurtado C, Kuroda H, Pera EM, De Robertis EM
Citation:
Cell. 2007 Nov 30;131(5):980-93
Epub:
Not Epub
Abstract:
BMP receptors determine the intensity of BMP signals via Smad1 C-terminal phosphorylations. Here we show that a finely...
Organism or Cell Type:
Xenopus
Citation Extract:
Fuentealba LC, Eivers E, Ikeda A, Hurtado C, Kuroda H, Pera EM, De Robertis EM. Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal. Cell. 2007 Nov 30;131(5):980-93.

Intracellular Delivery Strategies for Antisense Phosphorodiamidate Morpholino Oligos

Authors:
Ghosh C, Iversen P
Citation:
Antisense Nucleic Acid Drug Dev 2000 Aug;10(4):263-274
Epub:
Not Epub
Abstract:
Antisense oligonucleotides inhibit gene expression by interfering with transcription, translation, or splicing. They show great...
Delivery Method:
various
Organism or Cell Type:
cell culture: HeLa cells
Citation Extract:
Ghosh C, Iversen P. Intracellular Delivery Strategies for Antisense Phosphorodiamidate Morpholino Oligos. Antisense Nucleic Acid Drug Dev 2000 Aug;10(4):263-274.

Knockdown of AHR1A but not AHR1B exacerbates PAH and PCB-126 toxicity in zebrafish (Danio rerio) embryos

Authors:
Garner LV, Brown DR, Di Giulio RT
Citation:
Aquatic Tox. 2013;[Epub ahead of print] doi:10.1016/j.aquatox.2013.09.007
Epub:
Not Epub
Abstract:
Various environmental contaminants are known agonists for the aryl hydrocarbon receptor (AHR), which is highly conserved across...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Garner LV, Brown DR, Di Giulio RT. Knockdown of AHR1A but not AHR1B exacerbates PAH and PCB-126 toxicity in zebrafish (Danio rerio) embryos. Aquatic Tox. 2013;[Epub ahead of print] doi:10.1016/j.aquatox.2013.09.007.

Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos.

Authors:
Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI
Citation:
Dev Cell. 2005 Jan;8(1):109-16
Epub:
Not Epub
Abstract:
The differentiation of hematopoietic progenitors into erythroid or myeloid cell lineages is thought to depend upon relative...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI. Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos.. Dev Cell. 2005 Jan;8(1):109-16.

Low MAD2 expression levels associate with reduced progression-free survival in patients with high-grade serous epithelial ovarian cancer

Authors:
Furlong F, Fitzpatrick P, O'Toole S, Phelan S, McGrogan B, Maguire A, O'Grady A, Gallagher M, Prencipe M, McGoldrick A, McGettigan P, Brennan D, Sheils O, Martin C, W Kay E, O'Leary J, McCann A
Citation:
J Pathol. 2012 Apr;226(5):746-55. doi: 10.1002/path.3035. Epub 2012 Jan 17
Epub:
Not Epub
Abstract:
Epithelial ovarian cancer (EOC) has an innate susceptibility to become chemoresistant. Up to 30% of patients do not respond to...
Delivery Method:
Hiperfect (Qiagen)
Organism or Cell Type:
cell culture: A2780 ovarian cancer line
Citation Extract:
Furlong F, Fitzpatrick P, O'Toole S, Phelan S, McGrogan B, Maguire A, O'Grady A, Gallagher M, Prencipe M, McGoldrick A, McGettigan P, Brennan D, Sheils O, Martin C, W Kay E, O'Leary J, McCann A. Low MAD2 expression levels associate with reduced progression-free survival in patients with high-grade serous epithelial ovarian cancer. J Pathol. 2012 Apr;226(5):746-55. doi: 10.1002/path.3035. Epub 2012 Jan 17.

Methods for Evaluation of Antisense Mechanisms of Action

Authors:
Ghosh C, Stein D, Weller D, Iversen P
Citation:
In Antisense Technology Part A, General Methods, Methods of Delivery, and RNA Studies. Methods in Enzymology vol.313. 1999. (Ed. Ian Phillips) Academic Press. pp. 135-142
Epub:
Not Epub
Abstract:
No abstract available.
Citation Extract:
Ghosh C, Stein D, Weller D, Iversen P. Methods for Evaluation of Antisense Mechanisms of Action. In Antisense Technology Part A, General Methods, Methods of Delivery, and RNA Studies. Methods in Enzymology vol.313. 1999. (Ed. Ian Phillips) Academic Press. pp. 135-142.

MicroRNAs Regulate Brain Morphogenesis in Zebrafish

Authors:
Giraldez AJ, Cinalli RM, Glasner ME, Enright AJ, Thomson MJ, Baskerville S, Hammond SM, Bartel DP, Schier AF
Citation:
Science. 2005 May 6;308(5723):833-8.
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are small RNAs that regulate gene expression post-transcriptionally. To block all miRNA formation in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Giraldez AJ, Cinalli RM, Glasner ME, Enright AJ, Thomson MJ, Baskerville S, Hammond SM, Bartel DP, Schier AF. MicroRNAs Regulate Brain Morphogenesis in Zebrafish. Science. 2005 May 6;308(5723):833-8..

Mir-144 selectively regulates embryonic alpha-hemoglobin synthesis during primitive erythropoiesis

Authors:
Fu YF, Du TT, Dong M, Zhu KY, Jing CB, Zhang Y, Wang L, Fan HB, Chen Y, Jin Y, Yue GP, Chen SJ, Chen Z, Huang QH, Jing Q, Deng M, Liu TX
Citation:
Blood. 2009 Feb 5;113(6):1340-9. Epub 2008 Oct 21
Epub:
Not Epub
Abstract:
Precise transcriptional control of developmental stage-specific expression and switching of alpha- and beta-globin genes is...
Organism or Cell Type:
zebrafish
Citation Extract:
Fu YF, Du TT, Dong M, Zhu KY, Jing CB, Zhang Y, Wang L, Fan HB, Chen Y, Jin Y, Yue GP, Chen SJ, Chen Z, Huang QH, Jing Q, Deng M, Liu TX. Mir-144 selectively regulates embryonic alpha-hemoglobin synthesis during primitive erythropoiesis. Blood. 2009 Feb 5;113(6):1340-9. Epub 2008 Oct 21.

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