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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11399 scientific papers returned from the database with the search filters currently being used below.

Essential and opposing roles of zebrafish beta-catenins in the formation of dorsal axial structures and neurectoderm

Authors:
Bellipanni G, Varga M, Maegawa S, Imai Y, Kelly C, Myers AP, Chu F, Talbot WS, Weinberg ES
Citation:
Development. 2006 Apr;133(7):1299-309. Epub 2006 Mar 1
Epub:
Not Epub
Abstract:
In Xenopus, Wnt signals and their transcriptional effector beta-catenin are required for the development of dorsal axial...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bellipanni G, Varga M, Maegawa S, Imai Y, Kelly C, Myers AP, Chu F, Talbot WS, Weinberg ES. Essential and opposing roles of zebrafish beta-catenins in the formation of dorsal axial structures and neurectoderm. Development. 2006 Apr;133(7):1299-309. Epub 2006 Mar 1.

Evaluation of Exon-Skipping Strategies for Duchenne Muscular Dystrophy Utilizing Dystrophin-deficient Zebrafish

Authors:
Berger J, Berger S, Jacoby AS, Wilton SD, Currie PD
Citation:
J Cell Mol Med. 2011 Jan 20. doi: 10.1111/j.1582-4934.2011.01260.x. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Duchenne Muscular Dystrophy is a severe muscle wasting disease caused by mutations in the dystrophin gene. By utilising...
Organism or Cell Type:
zebrafish
Citation Extract:
Berger J, Berger S, Jacoby AS, Wilton SD, Currie PD. Evaluation of Exon-Skipping Strategies for Duchenne Muscular Dystrophy Utilizing Dystrophin-deficient Zebrafish. J Cell Mol Med. 2011 Jan 20. doi: 10.1111/j.1582-4934.2011.01260.x. [Epub ahead of print].

Evidence for a molecular mechanism of teratogenicity of SB-236057, a 5-HT1B receptor inverse agonist that alters axial formation

Authors:
Augustine-Rauch KA, Zhang QJ, Leonard JL, Chadderton A, Welsh MJ, Rami HK, Thompson M, Gaster L, Wier PJ
Citation:
Birth Defects Res A Clin Mol Teratol. 2004 Oct;70(10):789-807
Epub:
Not Epub
Abstract:
BACKGROUND: SB-236057 is a potent skeletal teratogen in rodents and rabbits, producing axial and posterior somite malformations...
Delivery Method:
Special Delivery
Organism or Cell Type:
Rat embryo, cultured
Citation Extract:
Augustine-Rauch KA, Zhang QJ, Leonard JL, Chadderton A, Welsh MJ, Rami HK, Thompson M, Gaster L, Wier PJ. Evidence for a molecular mechanism of teratogenicity of SB-236057, a 5-HT1B receptor inverse agonist that alters axial formation. Birth Defects Res A Clin Mol Teratol. 2004 Oct;70(10):789-807.

Evolutionarily conserved role of nucleostemin: controlling proliferation of stem/progenitor cells during early vertebrate development

Authors:
Beekman C, Nichane M, De Clercq S, Maetens M, Floss T, Wurst W, Bellefroid E, Marine JC
Citation:
Mol Cell Biol. 2006 Dec;26(24):9291-301. Epub 2006 Sep 25
Epub:
Not Epub
Abstract:
Nucleostemin (NS) is a putative GTPase expressed preferentially in the nucleoli of neuronal and embryonic stem cells and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Beekman C, Nichane M, De Clercq S, Maetens M, Floss T, Wurst W, Bellefroid E, Marine JC. Evolutionarily conserved role of nucleostemin: controlling proliferation of stem/progenitor cells during early vertebrate development. Mol Cell Biol. 2006 Dec;26(24):9291-301. Epub 2006 Sep 25.

Ewing sarcoma protein ewsr1 maintains mitotic integrity and proneural cell survival in the zebrafish embryo

Authors:
Azuma M, Embree LJ, Sabaawy H, Hickstein DD
Citation:
PLoS ONE. 2007 Oct 3;2(10):e979
Epub:
Not Epub
Abstract:
BACKGROUND: The Ewing sarcoma breakpoint region 1 gene (EWSR1), also known as EWS, is fused to a number of different partner...
Organism or Cell Type:
zebrafish
Citation Extract:
Azuma M, Embree LJ, Sabaawy H, Hickstein DD. Ewing sarcoma protein ewsr1 maintains mitotic integrity and proneural cell survival in the zebrafish embryo. PLoS ONE. 2007 Oct 3;2(10):e979.

Exon skipping with morpholino oligomers: new treatment option for cardiomyopathy in Duchenne muscular dystrophy?

Authors:
Bauer R, Katus HA, Müller OJ
Citation:
Cardiovasc Res. 2010. [Epub ahead of print]
Epub:
Not Epub
Abstract:
No abstract available
Citation Extract:
Bauer R, Katus HA, Müller OJ. Exon skipping with morpholino oligomers: new treatment option for cardiomyopathy in Duchenne muscular dystrophy?. Cardiovasc Res. 2010. [Epub ahead of print] .

Expression of LINE-1 retroposons is essential for murine preimplantation development

Authors:
Beraldi R, Pittoggi C, Sciamanna I, Mattei E, Spadafora C
Citation:
Mol Reprod Dev. 2006 Mar;73(3):279-87
Epub:
Not Epub
Abstract:
In higher eukaryotes, reverse transcriptase (RT) activities are encoded by a variety of endogenous retroviruses and...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse embryos,preimplantation
Citation Extract:
Beraldi R, Pittoggi C, Sciamanna I, Mattei E, Spadafora C. Expression of LINE-1 retroposons is essential for murine preimplantation development. Mol Reprod Dev. 2006 Mar;73(3):279-87.

Extra-embryonic syndecan 2 regulates organ primordia migration and fibrillogenesis throughout the zebrafish embryo

Authors:
Arrington CB, Yost HJ
Citation:
Development. 2009 Sep;136(18):3143-52
Epub:
Not Epub
Abstract:
One of the first steps in zebrafish heart and gut organogenesis is the migration of bilateral primordia to the midline to form...
Organism or Cell Type:
zebrafish
Citation Extract:
Arrington CB, Yost HJ. Extra-embryonic syndecan 2 regulates organ primordia migration and fibrillogenesis throughout the zebrafish embryo. Development. 2009 Sep;136(18):3143-52.

Fishing for a mechanism: using zebrafish to understand spinal muscular atrophy

Authors:
Beattie CE, Carrel TL, McWhorter ML
Citation:
J Child Neurol. 2007 Aug;22(8):995-1003. Review
Epub:
Not Epub
Abstract:
Motoneuron diseases cause paralysis and death due to loss of motoneurons that innervate skeletal muscle. Spinal muscular...
Organism or Cell Type:
zebrafish
Citation Extract:
Beattie CE, Carrel TL, McWhorter ML. Fishing for a mechanism: using zebrafish to understand spinal muscular atrophy. J Child Neurol. 2007 Aug;22(8):995-1003. Review.

FOXC1 is required for cell viability and resistance to oxidative stress in the eye through the transcriptional regulation of FOXO1A

Authors:
Berry FB, Skarie JM, Mirzayans F, Fortin Y, Hudson TJ, Raymond V, Link BA, Walter MA
Citation:
Hum Mol Genet. 2008 Feb 15;17(4):490-505. Epub 2007 Nov 9.
Epub:
Not Epub
Abstract:
Mutations in the human FOXC1 transcription factor gene underlie Axenfeld-Rieger (AR) syndrome, a disorder characterized by...
Organism or Cell Type:
zebrafish
Citation Extract:
Berry FB, Skarie JM, Mirzayans F, Fortin Y, Hudson TJ, Raymond V, Link BA, Walter MA. FOXC1 is required for cell viability and resistance to oxidative stress in the eye through the transcriptional regulation of FOXO1A. Hum Mol Genet. 2008 Feb 15;17(4):490-505. Epub 2007 Nov 9..

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