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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12067 scientific papers returned from the database with the search filters currently being used below.

Inhibition of flavivirus infections by antisense oligomers specifically suppressing viral translation and RNA replication

Authors:
Deas TS, Binduga-Gajewska I, Tilgner M, Ren P, Stein DA, Moulton HM, Iversen PL, Kauffman EB, Kramer LD, Shi PY
Citation:
J Virol. 2005 Apr;79(8):4599-609
Epub:
Not Epub
Abstract:
RNA elements within flavivirus genomes are potential targets for antiviral therapy. A panel of phosphorodiamidate morpholino...
Delivery Method:
peptide-coupled
Organism or Cell Type:
West Nile Virus
Citation Extract:
Deas TS, Binduga-Gajewska I, Tilgner M, Ren P, Stein DA, Moulton HM, Iversen PL, Kauffman EB, Kramer LD, Shi PY. Inhibition of flavivirus infections by antisense oligomers specifically suppressing viral translation and RNA replication. J Virol. 2005 Apr;79(8):4599-609.

Inhibition of human chorionic gonadotropin beta-subunit modulates the mitogenic effect of c-myc in human prostate cancer cells

Authors:
Devi GR, Oldenkamp JR, London CA, Iversen PL
Citation:
Prostate. 2002 Nov 1;53(3):200-10
Epub:
Not Epub
Abstract:
BACKGROUND: Amplification of the proto-oncogene c-myc has been identified as one of the most common genetic alterations in...
Delivery Method:
culture: scrape loading and syringe loading; mouse: IP injection
Organism or Cell Type:
cultures & mice: human DU145, PC-3, LNCaP prostate cancer lines, male athymic (Ncr nu/nu) mice
Citation Extract:
Devi GR, Oldenkamp JR, London CA, Iversen PL. Inhibition of human chorionic gonadotropin beta-subunit modulates the mitogenic effect of c-myc in human prostate cancer cells. Prostate. 2002 Nov 1;53(3):200-10.

Inhibition of p73 function by Pifithrin- as revealed by studies in zebrafish embryos

Authors:
Davidson W, Ren Q, Kari G, Kashi O, Dicker AP, Rodeck U
Citation:
Cell Cycle. 2008 Feb 11;7(9) [Epub ahead of print]
Epub:
Not Epub
Abstract:
The p53 family of proteins contains two members that have been implicated in sensitization of cells and organisms to genotoxic...
Organism or Cell Type:
zebrafish
Citation Extract:
Davidson W, Ren Q, Kari G, Kashi O, Dicker AP, Rodeck U. Inhibition of p73 function by Pifithrin- as revealed by studies in zebrafish embryos. Cell Cycle. 2008 Feb 11;7(9) [Epub ahead of print].

Integrin alpha(5)beta(1) and Fibronectin Regulate Polarized Cell Protrusions Required for Xenopus Convergence and Extension

Authors:
Davidson LA, Marsden M, Keller R, Desimone DW
Citation:
Curr Biol. 2006 May 9;16(9):833-44
Epub:
Not Epub
Abstract:
BACKGROUND: Integrin recognition of fibronectin is required for normal gastrulation including the mediolateral cell...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Davidson LA, Marsden M, Keller R, Desimone DW. Integrin alpha(5)beta(1) and Fibronectin Regulate Polarized Cell Protrusions Required for Xenopus Convergence and Extension. Curr Biol. 2006 May 9;16(9):833-44.

Interferon Regulatory Factor 6 Promotes Differentiation of the Periderm by Activating Expression of Grainyhead-Like 3

Authors:
de la Garza G, Schleiffarth JR, Dunnwald M, Mankad A, Weirather JL, Bonde G, Butcher S, Mansour TA, Kousa YA, Fukazawa CF, Houston DW, Manak JR, Schutte BC, Wagner DS, Cornell RA
Citation:
J Invest Dermatol. 2012 Aug 30. doi: 10.1038/jid.2012.269. [Epub ahead of print]
Epub:
Not Epub
Abstract:
IFN regulatory factor 6 (IRF6) is a transcription factor that, in mammals, is required for the differentiation of skin, breast...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
de la Garza G, Schleiffarth JR, Dunnwald M, Mankad A, Weirather JL, Bonde G, Butcher S, Mansour TA, Kousa YA, Fukazawa CF, Houston DW, Manak JR, Schutte BC, Wagner DS, Cornell RA. Interferon Regulatory Factor 6 Promotes Differentiation of the Periderm by Activating Expression of Grainyhead-Like 3. J Invest Dermatol. 2012 Aug 30. doi: 10.1038/jid.2012.269. [Epub ahead of print].

Knockdown of prothrombin in zebrafish

Authors:
Day K, Krishnegowda N, Jagadeeswaran P
Citation:
Blood Cells Mol Dis. 2004 Jan-Feb;32(1):191-8
Epub:
Not Epub
Abstract:
Thrombin is a serine protease generated from its zymogen, prothrombin, and plays a central role in the coagulation cascade. It...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Day K, Krishnegowda N, Jagadeeswaran P. Knockdown of prothrombin in zebrafish. Blood Cells Mol Dis. 2004 Jan-Feb;32(1):191-8.

Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning

Authors:
Davidson G, Mao B, Del Barco Barrantes I, Niehrs C
Citation:
Development. 2002 Dec;129(24):5587-96
Epub:
Not Epub
Abstract:
A gradient of Wnt/beta-catenin signalling formed by posteriorising Wnts and anteriorising Wnt antagonists regulates...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Davidson G, Mao B, Del Barco Barrantes I, Niehrs C. Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning. Development. 2002 Dec;129(24):5587-96.

LEK1 protein expression in normal and dysregulated cardiomyocyte mitosis

Authors:
Dees E, Robertson JB, Ashe M, Pabon-Pena LM, Bader D, Goodwin RL
Citation:
Anat Rec A Discov Mol Cell Evol Biol. 2005 Sep;286A(1):823-32.
Epub:
Not Epub
Abstract:
A defining characteristic of embryonic cells is their ability to divide rapidly, even in tissues such as cardiac muscle, which...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: mouse neonatal cardiac myocytes
Citation Extract:
Dees E, Robertson JB, Ashe M, Pabon-Pena LM, Bader D, Goodwin RL. LEK1 protein expression in normal and dysregulated cardiomyocyte mitosis. Anat Rec A Discov Mol Cell Evol Biol. 2005 Sep;286A(1):823-32..

Localized bacterial infection induces systemic activation of neutrophils through Cxcr2 signaling in zebrafish

Authors:
Deng Q, Sarris M, Bennin DA, Green JM, Herbomel P, Huttenlocher A
Citation:
J Leukoc Biol. 2013 Mar 8. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Neutrophils are the first line of defense against tissue damage and are rapidly mobilized to sites of bacterial infection....
Organism or Cell Type:
zebrafish
Citation Extract:
Deng Q, Sarris M, Bennin DA, Green JM, Herbomel P, Huttenlocher A. Localized bacterial infection induces systemic activation of neutrophils through Cxcr2 signaling in zebrafish. J Leukoc Biol. 2013 Mar 8. [Epub ahead of print].

Loss of selenoprotein N function causes disruption of muscle architecture in the zebrafish embryo

Authors:
Deniziak M, Thisse C, Rederstorff M, Hindelang C, Thisse B, Lescure A
Citation:
Exp Cell Res. 2007 Jan 1;313(1):156-67. Epub 2006 Oct 13.
Epub:
Not Epub
Abstract:
Mutations in the gene coding for selenoprotein N (SelN), a selenium containing protein of unknown function, cause different...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Deniziak M, Thisse C, Rederstorff M, Hindelang C, Thisse B, Lescure A. Loss of selenoprotein N function causes disruption of muscle architecture in the zebrafish embryo. Exp Cell Res. 2007 Jan 1;313(1):156-67. Epub 2006 Oct 13..

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