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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11304 scientific papers returned from the database with the search filters currently being used below.

Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota

Authors:
Bates JM, Akerlund J, Mittge E, Guillemin K
Citation:
Cell Host Microbe. 2007 Dec 13;2(6):371-82
Epub:
Not Epub
Abstract:
Vertebrates harbor abundant lipopolysaccharide (LPS) in their gut microbiota. Alkaline phosphatases can dephosphorylate and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bates JM, Akerlund J, Mittge E, Guillemin K. Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota. Cell Host Microbe. 2007 Dec 13;2(6):371-82.

Knockdown and overexpression of Unc-45b result in defective myofibril organization in skeletal muscles of zebrafish embryos

Authors:
Bernick E, Zhang P, Du S
Citation:
BMC Cell Biol. 2010 Sep 17;11(1):70. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Unc-45 is a myosin chaperone and a Hsp90 co-chaperone that plays a key role in muscle development. Genetic and...
Organism or Cell Type:
zebrafish
Citation Extract:
Bernick E, Zhang P, Du S. Knockdown and overexpression of Unc-45b result in defective myofibril organization in skeletal muscles of zebrafish embryos. BMC Cell Biol. 2010 Sep 17;11(1):70. [Epub ahead of print].

Knockdown of fbxl10/kdm2bb rescues chd7 morphant phenotype in a zebrafish model of CHARGE syndrome

Authors:
Balow SA, Pierce LX, Zentner GE, Conrad PA, Davis S, Sabaawy HE, McDermott BM, Scacheri PC
Citation:
Dev Biol. 2013; doi:10.1016/j.ydbio.2013.07.026
Epub:
Not Epub
Abstract:
CHARGE syndrome is a sporadic autosomal-dominant genetic disorder characterized by a complex array of birth defects so named...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Balow SA, Pierce LX, Zentner GE, Conrad PA, Davis S, Sabaawy HE, McDermott BM, Scacheri PC. Knockdown of fbxl10/kdm2bb rescues chd7 morphant phenotype in a zebrafish model of CHARGE syndrome. Dev Biol. 2013; doi:10.1016/j.ydbio.2013.07.026.

L1.1 is involved in spinal cord regeneration in adult zebrafish

Authors:
Becker CG, Lieberoth BC, Morellini F, Feldner J, Becker T, Schachner M
Citation:
J Neurosci. 2004 Sep 8;24(36):7837-42
Epub:
Not Epub
Abstract:
Adult zebrafish, in contrast to mammals, regrow axons descending from the brainstem after spinal cord transection. L1.1, a...
Delivery Method:
Gelfoam at lesion
Organism or Cell Type:
zebrafish
Citation Extract:
Becker CG, Lieberoth BC, Morellini F, Feldner J, Becker T, Schachner M. L1.1 is involved in spinal cord regeneration in adult zebrafish. J Neurosci. 2004 Sep 8;24(36):7837-42.

LEK1 Is a Potential Inhibitor of Pocket Protein-mediated Cellular Processes.

Authors:
Ashe M, Pabon-Pena L, Dees E, Price KL, Bader D.
Citation:
J Biol Chem. 2004 Jan 2;279(1):664-76. Epub 2003 Oct 10.
Epub:
Not Epub
Abstract:
LEK1, a member of the LEK family of proteins, is ubiquitously expressed in developing murine tissues. Our current studies are...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: mouse 3T3 fibroblasts and C2C12 myoblasts
Citation Extract:
Ashe M, Pabon-Pena L, Dees E, Price KL, Bader D.. LEK1 Is a Potential Inhibitor of Pocket Protein-mediated Cellular Processes.. J Biol Chem. 2004 Jan 2;279(1):664-76. Epub 2003 Oct 10..

Lessons from morpholino-based screening in zebrafish

Authors:
Bedell VM, Westcot SE, Ekker SC
Citation:
Briefings in Functional Genomics. 2011;[Epub ahead of print July 10] doi:10.1093/bfgp/elr021
Epub:
Not Epub
Abstract:
Morpholino oligonucleotides (MOs) are an effective, gene-specific antisense knockdown technology used in many model systems....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bedell VM, Westcot SE, Ekker SC. Lessons from morpholino-based screening in zebrafish. Briefings in Functional Genomics. 2011;[Epub ahead of print July 10] doi:10.1093/bfgp/elr021.

Loss-of-function mutations in RAB18 cause Warburg micro syndrome.

Authors:
Bem D, Yoshimura S, Nunes-Bastos R, Bond FC, Kurian MA, Rahman F, Handley MT, Hadzhiev Y, Masood I, Straatman-Iwanowska AA, Cullinane AR, McNeill A, Pasha SS, Kirby GA, Foster K, Ahmed Z, Morton JE, Williams D, Graham JM, Dobyns WB, Burglen L, Ainsworth JR, Gissen P, Müller F, Maher ER, Barr FA, Aligianis IA
Citation:
Am J Hum Genet. 2011 Apr 8;88(4):499-507. Erratum in: Am J Hum Genet. 2011 May 13;88(5):678. Bond, Frances F [corrected to Bond, Frances C].
Epub:
Not Epub
Abstract:
Warburg Micro syndrome and Martsolf syndrome are heterogenous autosomal-recessive developmental disorders characterized by...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bem D, Yoshimura S, Nunes-Bastos R, Bond FC, Kurian MA, Rahman F, Handley MT, Hadzhiev Y, Masood I, Straatman-Iwanowska AA, Cullinane AR, McNeill A, Pasha SS, Kirby GA, Foster K, Ahmed Z, Morton JE, Williams D, Graham JM, Dobyns WB, Burglen L, Ainsworth JR, Gissen P, Müller F, Maher ER, Barr FA, Aligianis IA. Loss-of-function mutations in RAB18 cause Warburg micro syndrome.. Am J Hum Genet. 2011 Apr 8;88(4):499-507. Erratum in: Am J Hum Genet. 2011 May 13;88(5):678. Bond, Frances F [corrected to Bond, Frances C]. .

Melanoma revives an embryonic migration program to promote plasticity and invasion

Authors:
Bailey CM, Morrison JA, Kulesa PM
Citation:
Pigment Cell & Melanoma Research. 2012;[Epub ahead of print] doi:10.1111/j.1755-148X.2012.01025.x
Epub:
Not Epub
Abstract:
Cancer cells must regulate plasticity and invasion to survive and metastasize. However, the identification of targetable...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: chick
Citation Extract:
Bailey CM, Morrison JA, Kulesa PM. Melanoma revives an embryonic migration program to promote plasticity and invasion. Pigment Cell & Melanoma Research. 2012;[Epub ahead of print] doi:10.1111/j.1755-148X.2012.01025.x.

miR-124 acts through CoREST to control onset of Sema3A sensitivity in navigating retinal growth cones

Authors:
Baudet ML, Zivraj KH, Abreu-Goodger C, Muldal A, Armisen J, Blenkiron C, Goldstein LD, Miska EA, Holt CE
Citation:
Nat Neurosci. 2011 Dec 4;15(1):29-38. doi: 10.1038/nn.2979
Epub:
Not Epub
Abstract:
During axon pathfinding, growth cones commonly show changes in sensitivity to guidance cues that follow a cell-intrinsic...
Delivery Method:
Electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Baudet ML, Zivraj KH, Abreu-Goodger C, Muldal A, Armisen J, Blenkiron C, Goldstein LD, Miska EA, Holt CE. miR-124 acts through CoREST to control onset of Sema3A sensitivity in navigating retinal growth cones. Nat Neurosci. 2011 Dec 4;15(1):29-38. doi: 10.1038/nn.2979.

miR-204 Targeting of Ankrd13A Controls Both Mesenchymal Neural Crest and Lens Cell Migration

Authors:
Avellino R, Carrella S, Pirozzi M, Risolino M, Salierno FG, Franco P, Stoppelli P, Verde P, Banfi S, Conte I
Citation:
PLoS ONE. 2013;8(4):e61099. doi:10.1371/journal.pone.0061099
Epub:
Not Epub
Abstract:
Loss of cell adhesion and enhancement of cell motility contribute to epithelial-to-mesenchymal transition during development....
Delivery Method:
Microinjection
Organism or Cell Type:
medaka
Citation Extract:
Avellino R, Carrella S, Pirozzi M, Risolino M, Salierno FG, Franco P, Stoppelli P, Verde P, Banfi S, Conte I. miR-204 Targeting of Ankrd13A Controls Both Mesenchymal Neural Crest and Lens Cell Migration. PLoS ONE. 2013;8(4):e61099. doi:10.1371/journal.pone.0061099.

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