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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11304 scientific papers returned from the database with the search filters currently being used below.

Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity

Authors:
Benjamin JM, Torke SJ, Demeler B, McGarry TJ
Citation:
J Biol Chem. 2004 Oct 29;279(44):45957-68. Epub 2004 Aug 12
Epub:
Not Epub
Abstract:
Geminin is an unstable regulatory protein that affects both cell division and cell differentiation. Geminin inhibits a second...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Benjamin JM, Torke SJ, Demeler B, McGarry TJ. Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity. J Biol Chem. 2004 Oct 29;279(44):45957-68. Epub 2004 Aug 12.

Gene selective mRNA cleavage inhibits the development of Plasmodium falciparum

Authors:
Augagneur Y, Wesolowski D, Tae HS, Altman S, Mamoun CB
Citation:
PNAS. 2012;[Epub ahead of print] doi:10.1073/pnas.1203516109
Epub:
Not Epub
Abstract:
Unique peptide-morpholino oligomer (PMO) conjugates have been designed to bind and promote the cleavage of specific mRNA as a...
Delivery Method:
peptide-coupled
Organism or Cell Type:
Plasmodium falciparum
Citation Extract:
Augagneur Y, Wesolowski D, Tae HS, Altman S, Mamoun CB. Gene selective mRNA cleavage inhibits the development of Plasmodium falciparum. PNAS. 2012;[Epub ahead of print] doi:10.1073/pnas.1203516109 .

Gene-environment interactions: neurodegeneration in non-mammals and mammals

Authors:
Aschner M, Levin ED, Suñol C, Olopade JO, Helmcke KJ, Avila DS, Sledge D, Ali RH, Upchurch L, Donerly S, Linney E, Forsby A, Ponnuru P, Connor JR
Citation:
Neurotoxicology. 2010 Sep;31(5):582-8. Epub 2010 Mar 30. Review
Epub:
Not Epub
Abstract:
The understanding of how environmental exposures interact with genetics in central nervous system dysfunction has gained great...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Aschner M, Levin ED, Suñol C, Olopade JO, Helmcke KJ, Avila DS, Sledge D, Ali RH, Upchurch L, Donerly S, Linney E, Forsby A, Ponnuru P, Connor JR. Gene-environment interactions: neurodegeneration in non-mammals and mammals. Neurotoxicology. 2010 Sep;31(5):582-8. Epub 2010 Mar 30. Review.

Haemodynamically dependent valvulogenesis of zebrafish heart is mediated by flow-dependent expression of miR-21

Authors:
Banjo T, Grajcarek J, Yoshino D, Osada H, Miyasaka KY, Kida YS, Ueki Y, Nagayama K, Kawakami K, Matsumoto T, Sato M, Ogura T
Citation:
Nature Comm. 2013;4:article1978 doi:10.1038/ncomms2978
Epub:
Not Epub
Abstract:
Heartbeat is required for normal development of the heart, and perturbation of intracardiac flow leads to morphological defects...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Banjo T, Grajcarek J, Yoshino D, Osada H, Miyasaka KY, Kida YS, Ueki Y, Nagayama K, Kawakami K, Matsumoto T, Sato M, Ogura T. Haemodynamically dependent valvulogenesis of zebrafish heart is mediated by flow-dependent expression of miR-21. Nature Comm. 2013;4:article1978 doi:10.1038/ncomms2978.

Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation

Authors:
Bakkers J, Kramer C, Pothof J, Quaedvlieg NE, Spaink HP, Hammerschmidt M
Citation:
Development. 2004 Feb; 131(3): 525-537
Epub:
Not Epub
Abstract:
The large extracellular polysaccharide Hyaluronan (HA) and its synthesizing enzymes (Has) have been implicated in regulating...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bakkers J, Kramer C, Pothof J, Quaedvlieg NE, Spaink HP, Hammerschmidt M. Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation. Development. 2004 Feb; 131(3): 525-537.

Hedgehog regulated Slit expression determines commissure and glial cell position in the zebrafish forebrain.

Authors:
Barresi MJ, Hutson LD, Chien CB, Karlstrom RO.
Citation:
Development. 2005 Aug;132(16):3643-56. Epub 2005 Jul 20.
Epub:
Not Epub
Abstract:
Three major axon pathways cross the midline of the vertebrate forebrain early in embryonic development: the postoptic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Barresi MJ, Hutson LD, Chien CB, Karlstrom RO.. Hedgehog regulated Slit expression determines commissure and glial cell position in the zebrafish forebrain.. Development. 2005 Aug;132(16):3643-56. Epub 2005 Jul 20..

Hoxa2 knockdown in Xenopus results in hyoid to mandibular homeosis

Authors:
Baltzinger M, Ori M, Pasqualetti M, Nardi I, Rijli FM
Citation:
Dev Dyn. 2005 Dec;234(4):858-67.
Epub:
Not Epub
Abstract:
The skeletal structures of the face and throat are derived from cranial neural crest cells (NCCs) that migrate from the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Baltzinger M, Ori M, Pasqualetti M, Nardi I, Rijli FM. Hoxa2 knockdown in Xenopus results in hyoid to mandibular homeosis. Dev Dyn. 2005 Dec;234(4):858-67..

Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in zebrafish

Authors:
Becker JR, Deo RC, Werdich AA, Panàkovà D, Coy S, Macrae CA
Citation:
Dis Model Mech. 2011 Jan 18. [Epub ahead of print]
Epub:
Not Epub
Abstract:
To assess the effects during cardiac development of mutations that cause human cardiomyopathy, we modeled a sarcomeric gene...
Organism or Cell Type:
zebrafish
Citation Extract:
Becker JR, Deo RC, Werdich AA, Panàkovà D, Coy S, Macrae CA. Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in zebrafish. Dis Model Mech. 2011 Jan 18. [Epub ahead of print].

Identification and dissection of a key enhancer mediating cranial neural crest specific expression of transcription factor, Ets-1

Authors:
Barembaum M, Bronner ME
Citation:
Dev Biol. 2013 Aug 19. doi:pii: S0012-1606(13)00421-1. 10.1016/j.ydbio.2013.08.009. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Neural crest cells form diverse derivatives that vary according to their level of origin along the body axis, with only cranial...
Delivery Method:
Electroporation
Organism or Cell Type:
chick (Gallus gallus)
Citation Extract:
Barembaum M, Bronner ME. Identification and dissection of a key enhancer mediating cranial neural crest specific expression of transcription factor, Ets-1. Dev Biol. 2013 Aug 19. doi:pii: S0012-1606(13)00421-1. 10.1016/j.ydbio.2013.08.009. [Epub ahead of print].

IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy

Authors:
Beales PL, Bland E, Tobin JL, Bacchelli C, Tuysuz B, Hill J, Rix S, Pearson CG, Kai M, Hartley J, Johnson C, Irving M, Elcioglu N, Winey M, Tada M, Scambler PJ
Citation:
Nat Genet. 2007 Jun;39(6):727-9. Epub 2007 Apr 29
Epub:
Not Epub
Abstract:
Jeune asphyxiating thoracic dystrophy, an autosomal recessive chondrodysplasia, often leads to death in infancy because of a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Beales PL, Bland E, Tobin JL, Bacchelli C, Tuysuz B, Hill J, Rix S, Pearson CG, Kai M, Hartley J, Johnson C, Irving M, Elcioglu N, Winey M, Tada M, Scambler PJ. IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy. Nat Genet. 2007 Jun;39(6):727-9. Epub 2007 Apr 29.

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