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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Zebrafish KLF4 is essential for anterior mesendoderm/pre-polster differentiation and hatching

Authors:
Gardiner MR, Daggett DF, Zon LI, Perkins AC
Citation:
Dev Dyn. 2005 Dec;234(4):992-6.
Epub:
Not Epub
Abstract:
Gene knockout studies of Kruppel-like factors (KLFs) in mice have shown essential roles in organogenesis. A screen for KLF...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gardiner MR, Daggett DF, Zon LI, Perkins AC. Zebrafish KLF4 is essential for anterior mesendoderm/pre-polster differentiation and hatching. Dev Dyn. 2005 Dec;234(4):992-6..

Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs

Authors:
Giraldez AJ, Mishima Y, Rihel J, Grocock RJ, Van Dongen S, Inoue K, Enright AJ, Schier AF
Citation:
Science. 2006 Apr 7;312(5770):75-9. Epub 2006 Feb 16
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) comprise 1 to 3% of all vertebrate genes, but their in vivo functions and mechanisms of action remain...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Giraldez AJ, Mishima Y, Rihel J, Grocock RJ, Van Dongen S, Inoue K, Enright AJ, Schier AF. Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science. 2006 Apr 7;312(5770):75-9. Epub 2006 Feb 16.

Zebrafish Tie-2 shares a redundant role with Tie-1 in heart development and regulates vessel integrity

Authors:
Gjini E, Hekking LH, Küchler A, Saharinen P, Wienholds E, Post JA, Alitalo K, Schulte-Merker S
Citation:
Dis Model Mech. 2010 Nov 2. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Tie-2 is a member of the receptor tyrosine kinase family and is required for vascular remodeling and maintenance of mammalian...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gjini E, Hekking LH, Küchler A, Saharinen P, Wienholds E, Post JA, Alitalo K, Schulte-Merker S. Zebrafish Tie-2 shares a redundant role with Tie-1 in heart development and regulates vessel integrity. Dis Model Mech. 2010 Nov 2. [Epub ahead of print].

Xenopus marginal coil (Xmc), a novel FGF inducible cytosolic coiled-coil protein regulating gastrulation movements

Authors:
Frazzetto G, Klingbeil P, Bouwmeester T
Citation:
Mech Dev. 2002 Apr;113(1):3-14
Epub:
Not Epub
Abstract:
Gastrulation in vertebrates is a highly dynamic process driven by convergent extension movements of internal mesodermal cells,...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Frazzetto G, Klingbeil P, Bouwmeester T. Xenopus marginal coil (Xmc), a novel FGF inducible cytosolic coiled-coil protein regulating gastrulation movements. Mech Dev. 2002 Apr;113(1):3-14.

A hierarchy of Runx transcription factors modulate the onset of chondrogenesis in craniofacial endochondral bones in zebrafish

Authors:
Flores MV, Lam EY, Crosier P, Crosier K
Citation:
Dev Dyn. 2006 Nov;235(11):3166-76.
Epub:
Not Epub
Abstract:
The Runx (runt-related) family of transcription factors are important regulators of cell fate decisions in early embryonic...
Organism or Cell Type:
zebrafish
Citation Extract:
Flores MV, Lam EY, Crosier P, Crosier K. A hierarchy of Runx transcription factors modulate the onset of chondrogenesis in craniofacial endochondral bones in zebrafish. Dev Dyn. 2006 Nov;235(11):3166-76..

A Highly Conserved Poc1 Protein Characterized in Embryos of the Hydrozoan Clytia hemisphaerica: Localization and Functional Studies

Authors:
Fourrage C, Chevalier S, Houliston E
Citation:
PLoS ONE. 2010;5(11): e13994. doi:10.1371/journal.pone.0013994
Epub:
Not Epub
Abstract:
Poc1 (Protein of Centriole 1) proteins are highly conserved WD40 domain-containing centriole components, well characterized in...
Delivery Method:
Microinjection
Organism or Cell Type:
Clytia hemisphaerica
Citation Extract:
Fourrage C, Chevalier S, Houliston E. A Highly Conserved Poc1 Protein Characterized in Embryos of the Hydrozoan Clytia hemisphaerica: Localization and Functional Studies. PLoS ONE. 2010;5(11): e13994. doi:10.1371/journal.pone.0013994.

A mild neurofibromatosis type 1 phenotype produced by the combination of the benign nature of a leaky NF1-splice mutation and the presence of a complex mosaicism

Authors:
Fernández-Rodríguez J, Castellsagué J, Benito L, Benavente Y, Capellà G, Blanco I, Serra E, Lázaro C
Citation:
Hum Mutat. 2011 Mar 10. doi: 10.1002/humu.21500. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Here we analyze the genetic and molecular basis responsible for a very benign phenotype observed in a NF1 patient....
Citation Extract:
Fernández-Rodríguez J, Castellsagué J, Benito L, Benavente Y, Capellà G, Blanco I, Serra E, Lázaro C. A mild neurofibromatosis type 1 phenotype produced by the combination of the benign nature of a leaky NF1-splice mutation and the presence of a complex mosaicism. Hum Mutat. 2011 Mar 10. doi: 10.1002/humu.21500. [Epub ahead of print].

A novel and critical role for Oct4 as a regulator of the maternal-embryonic transition

Authors:
Foygel K, Choi B, Jun S, Leong DE, Lee A, Wong CC, Zuo E, Eckart M, Reijo Pera RA, Wong WH, Yao MW
Citation:
PLoS ONE. 2008;3(12):e4109. Epub 2008 Dec 31
Epub:
Not Epub
Abstract:
BACKGROUND: Compared to the emerging embryonic stem cell (ESC) gene network, little is known about the dynamic gene network...
Delivery Method:
Microinjection
Organism or Cell Type:
Mouse embryo
Citation Extract:
Foygel K, Choi B, Jun S, Leong DE, Lee A, Wong CC, Zuo E, Eckart M, Reijo Pera RA, Wong WH, Yao MW. A novel and critical role for Oct4 as a regulator of the maternal-embryonic transition. PLoS ONE. 2008;3(12):e4109. Epub 2008 Dec 31.

A role for GATA factors in Xenopus gastrulation movements

Authors:
Fletcher G, Jones GE, Patient R, Snape A
Citation:
Mech Dev. 2006 Oct;123(10):730-45. Epub 2006 Jul 26.
Epub:
Not Epub
Abstract:
Gastrulation movements in Xenopus laevis are becoming increasingly well characterised, however the molecular mechanisms...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Fletcher G, Jones GE, Patient R, Snape A. A role for GATA factors in Xenopus gastrulation movements. Mech Dev. 2006 Oct;123(10):730-45. Epub 2006 Jul 26..

A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish

Authors:
Fish JE, Wythe JD, Xiao T, Bruneau BG, Stainier DY, Srivastava D, Woo S
Citation:
Development. 2011 Apr;138(7):1409-19
Epub:
Not Epub
Abstract:
Members of the Slit family of secreted ligands interact with Roundabout (Robo) receptors to provide guidance cues for many cell...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fish JE, Wythe JD, Xiao T, Bruneau BG, Stainier DY, Srivastava D, Woo S. A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish. Development. 2011 Apr;138(7):1409-19.

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