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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12092 scientific papers returned from the database with the search filters currently being used below.

Heat-shock protein 90alpha1 is required for organized myofibril assembly in skeletal muscles of zebrafish embryos

Authors:
Du SJ, Li H, Bian Y, Zhong Y
Citation:
Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):554-9. Epub 2008 Jan 8
Epub:
Not Epub
Abstract:
Heat-shock protein 90alpha (Hsp90alpha) is a member of the molecular chaperone family involved in protein folding and assembly...
Organism or Cell Type:
zebrafish
Citation Extract:
Du SJ, Li H, Bian Y, Zhong Y. Heat-shock protein 90alpha1 is required for organized myofibril assembly in skeletal muscles of zebrafish embryos. Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):554-9. Epub 2008 Jan 8.

High-throughput target validation in model organisms

Authors:
Doan TN, Eilertson CD, Rubinstein AL
Citation:
Drug Discovery Today: TARGETS. 2004 3(5):191-7
Epub:
Not Epub
Abstract:
Modern drug discovery includes a progression from the identification of molecular targets pertinent to disease processes to the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Doan TN, Eilertson CD, Rubinstein AL. High-throughput target validation in model organisms. Drug Discovery Today: TARGETS. 2004 3(5):191-7.

HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages

Authors:
Dressman J, Kincer J, Matveev SV, Guo L, Greenberg RN, Guerin T, Meade D, Li XA, Zhu W, Uittenbogaard A, Wilson ME, Smart EJ
Citation:
J Clin Invest. 2003 Feb;111(3):389-97
Epub:
Not Epub
Abstract:
Protease inhibitors decrease the viral load in HIV patients, however the patients develop hypertriglyceridemia,...
Delivery Method:
oligo bathing
Organism or Cell Type:
cell culture: THP-1 cells
Citation Extract:
Dressman J, Kincer J, Matveev SV, Guo L, Greenberg RN, Guerin T, Meade D, Li XA, Zhu W, Uittenbogaard A, Wilson ME, Smart EJ. HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages. J Clin Invest. 2003 Feb;111(3):389-97.

Inhibition of brain tumor growth by intravenous poly(beta-L-malic) acid nanobioconjugate with pH-dependent drug release

Authors:
Ding H, Inoue S, Ljubimov AV, Patil R, Portilla-Arias J, Hu J, Konda B, Wawrowsky KA, Fujita M, Karabalin N, Sasaki T, Black KL, Holler E, Ljubimova JY
Citation:
Proc Natl Acad Sci U S A. 2010 Oct 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Effective treatment of brain neurological disorders such as Alzheimer's disease, multiple sclerosis, or tumors should be...
Delivery Method:
Polycefin: poly(malic acid) from Physarum polycephalum
Organism or Cell Type:
mice (athymic), human glioblastoma cells U87MG
Citation Extract:
Ding H, Inoue S, Ljubimov AV, Patil R, Portilla-Arias J, Hu J, Konda B, Wawrowsky KA, Fujita M, Karabalin N, Sasaki T, Black KL, Holler E, Ljubimova JY. Inhibition of brain tumor growth by intravenous poly(beta-L-malic) acid nanobioconjugate with pH-dependent drug release. Proc Natl Acad Sci U S A. 2010 Oct 4. [Epub ahead of print].

Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: A quantifiable method for gene knockdown

Authors:
Draper BW, Morcos PA, Kimmel CB
Citation:
Genesis. 2001 Jul;30(3):154-6
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Draper BW, Morcos PA, Kimmel CB. Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: A quantifiable method for gene knockdown. Genesis. 2001 Jul;30(3):154-6.

Intracardial Embryonic Delivery of Developmental Modifiers In Utero

Authors:
Domínguez-Bendala J, Álvarez-Cubela S, Nieto M, Vargas N, Espino-Grosso P, Sacher VY, Pileggi A, García E, Ricordi C, Inverardi L, Pastori RL
Citation:
Cold Spring Harb Protoc. 2012;doi:10.1101/pdb.prot069427
Epub:
Not Epub
Abstract:
Our knowledge of organ ontogeny is largely based on loss-of-function (knockout) or gain-of-function (transgenesis) approaches....
Delivery Method:
Vivo-Morpholino, transplacental
Organism or Cell Type:
mice
Citation Extract:
Domínguez-Bendala J, Álvarez-Cubela S, Nieto M, Vargas N, Espino-Grosso P, Sacher VY, Pileggi A, García E, Ricordi C, Inverardi L, Pastori RL. Intracardial Embryonic Delivery of Developmental Modifiers In Utero. Cold Spring Harb Protoc. 2012;doi:10.1101/pdb.prot069427.

Intralineage directional Notch signaling regulates self-renewal and differentiation of asymmetrically dividing radial glia

Authors:
Dong Z, Yang N, Yeo SY, Chitnis A, Guo S
Citation:
Neuron. 2012 Apr 12;74(1):65-78. doi: 10.1016/j.neuron.2012.01.031.
Epub:
Not Epub
Abstract:
Asymmetric division of progenitor/stem cells generates both self-renewing and differentiating progeny and is fundamental to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dong Z, Yang N, Yeo SY, Chitnis A, Guo S. Intralineage directional Notch signaling regulates self-renewal and differentiation of asymmetrically dividing radial glia. Neuron. 2012 Apr 12;74(1):65-78. doi: 10.1016/j.neuron.2012.01.031..

Intronic miR-26b controls neuronal differentiation by repressing its host transcript, ctdsp2

Authors:
Dill H, Linder B, Fehr A, Fischer U
Citation:
Genes Dev. 2012;26:25-30 doi:10.1101/gad.177774.111
Epub:
Not Epub
Abstract:
Differentiation of neural stem cells (NSCs) to neurons requires the activation of genes controlled by the repressor element 1 (...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dill H, Linder B, Fehr A, Fischer U. Intronic miR-26b controls neuronal differentiation by repressing its host transcript, ctdsp2. Genes Dev. 2012;26:25-30 doi:10.1101/gad.177774.111.

Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut

Authors:
Dush MK, Nascone-Yoder NM
Citation:
Development. 2013 Apr;140(7):1457-66. doi: 10.1242/dev.086850. Epub 2013 Mar 5
Epub:
Not Epub
Abstract:
Tissue elongation is a fundamental morphogenetic process that generates the proper anatomical topology of the body plan and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Dush MK, Nascone-Yoder NM. Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut. Development. 2013 Apr;140(7):1457-66. doi: 10.1242/dev.086850. Epub 2013 Mar 5.

Kctd15 inhibits neural crest formation by attenuating Wnt/beta-catenin signaling output

Authors:
Dutta S, Dawid IB
Citation:
Development. 2010 Sep;137(18):3013-8. Epub 2010 Aug 4
Epub:
Not Epub
Abstract:
Neural crest (NC) precursors are stem cells that are capable of forming many cell types after migration to different locations...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dutta S, Dawid IB. Kctd15 inhibits neural crest formation by attenuating Wnt/beta-catenin signaling output. Development. 2010 Sep;137(18):3013-8. Epub 2010 Aug 4.

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