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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12092 scientific papers returned from the database with the search filters currently being used below.
There are 12092 scientific papers returned from the database with the search filters currently being used below.
Mutations in the human SIX3 gene in holoprosencephaly are loss of function
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Citation:
Hum Mol Genet. 2008 Dec 15;17(24):3919-28. Epub 2008 Sep 12 Epub:
Not Epub Abstract:
Holoprosencephaly (HPE) is the most common developmental anomaly of the human forebrain; however, the genetics of this... Delivery Method:
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zebrafish Citation Extract: Domené S, Roessler E, El-Jaick KB, Snir M, Brown JL, Vélez JI, Bale S, Lacbawan F, Muenke M, Feldman B. Mutations in the human SIX3 gene in holoprosencephaly are loss of function. Hum Mol Genet. 2008 Dec 15;17(24):3919-28. Epub 2008 Sep 12. |
Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm
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Citation:
Nat Genet. 2012 Sep 30. doi: 10.1038/ng.2421. [Epub ahead of print] Epub:
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Elevated transforming growth factor (TGF)-β signaling has been implicated in the pathogenesis of syndromic presentations of... Delivery Method:
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zebrafish Citation Extract: Doyle AJ, Doyle JJ, Bessling SL, Maragh S, Lindsay ME, Schepers D, Gillis E, Mortier G, Homfray T, Sauls K, Norris RA, Huso ND, Leahy D, Mohr DW, Caulfield MJ, Scott AF, Destrée A, Hennekam RC, Arn PH, Curry CJ, Van Laer L, McCallion AS, Loeys BL, Dietz HC. Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm. Nat Genet. 2012 Sep 30. doi: 10.1038/ng.2421. [Epub ahead of print]. |
Mutations in vacuolar H(+)-ATPase subunits lead to biliary developmental defects in zebrafish
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Citation:
Dev Biol. 2012 Mar 16. [Epub ahead of print] Epub:
Not Epub Abstract:
We identified three zebrafish mutants with defects in biliary development. One of these mutants, pekin (pn), also demonstrated... Organism or Cell Type:
zebrafish Citation Extract: EauClaire SF, Cui S, Ma L, Matous J, Marlow FL, Gupta T, Burgess HA, Abrams EW, Kapp LD, Granato M, Mullins MC, Matthews RP. Mutations in vacuolar H(+)-ATPase subunits lead to biliary developmental defects in zebrafish. Dev Biol. 2012 Mar 16. [Epub ahead of print]. |
Neural and eye-specific defects associated with loss of the Imitation Switch (ISWI) chromatin remodeler in Xenopus laevis
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Citation:
Mech Dev. 2005 Nov;122(11):1157-70. Epub 2005 Aug 29. Epub:
Not Epub Abstract:
Imitation Switch (ISWI) is a member of the SWI2/SNF2 superfamily of ATP-dependent chromatin remodelers, which regulate... Delivery Method:
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Xenopus laevis Citation Extract: Dirscherl SS, Henry JJ, Krebs JE. Neural and eye-specific defects associated with loss of the Imitation Switch (ISWI) chromatin remodeler in Xenopus laevis. Mech Dev. 2005 Nov;122(11):1157-70. Epub 2005 Aug 29.. |
Nkx6 genes pattern the frog neural plate and Nkx6.1 is necessary for motoneuron axon projection
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Citation:
Dev Biol. 2010 Oct 27. [Epub ahead of print] Epub:
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Neuronal subtypes originate from an undifferentiated neural epithelium that is progressively divided into progenitor domains by... Delivery Method:
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X.laevis & X.tropicalis Citation Extract: Dichmann DS, Harland RM. Nkx6 genes pattern the frog neural plate and Nkx6.1 is necessary for motoneuron axon projection. Dev Biol. 2010 Oct 27. [Epub ahead of print]. |
Nodal and BMP2/4 pattern the mesoderm and endoderm during development of the sea urchin embryo
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Citation:
Development. 2010 Jan;137(2):223-35 Epub:
Not Epub Abstract:
Nodal factors play fundamental roles in induction and patterning of the mesoderm and endoderm in vertebrates, but whether this... Delivery Method:
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sea urchin Citation Extract: Duboc V, Lapraz F, Saudemont A, Bessodes N, Mekpoh F, Haillot E, Quirin M, Lepage T. Nodal and BMP2/4 pattern the mesoderm and endoderm during development of the sea urchin embryo. Development. 2010 Jan;137(2):223-35. |
Nodal and BMP2/4 Signaling Organizes the Oral-Aboral Axis of the Sea Urchin Embryo
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Citation:
Dev Cell. 2004 Mar;6(3):397-410 Epub:
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In the sea urchin embryo, the oral-aboral axis is specified after fertilization by mechanisms that are largely unknown. We... Delivery Method:
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Sea urchin, Strongylocentrotus purpuratus Citation Extract: Duboc V, Rottinger E, Besnardeau L, Lepage T. Nodal and BMP2/4 Signaling Organizes the Oral-Aboral Axis of the Sea Urchin Embryo. Dev Cell. 2004 Mar;6(3):397-410. |
On the embryonic origin of adult melanophores: the role of ErbB and Kit signalling in establishing melanophore stem cells in zebrafish
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Citation:
Development. 2013 Jan 30. [Epub ahead of print] Epub:
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Pigment cells in vertebrates are derived from the neural crest (NC), a pluripotent and migratory embryonic cell population. In... Organism or Cell Type:
zebrafish Citation Extract: Dooley CM, Mongera A, Walderich B, Nüsslein-Volhard C. On the embryonic origin of adult melanophores: the role of ErbB and Kit signalling in establishing melanophore stem cells in zebrafish. Development. 2013 Jan 30. [Epub ahead of print]. |
p90Rsk is not involved in cytostatic factor arrest in mouse oocytes
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Citation:
J Cell Biol. 2005 Apr 25;169(2):227-31. Epub 2005 Apr 18. Epub:
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Vertebrate oocytes arrest in metaphase of the second meiotic division (MII), where they maintain a high cdc2/cyclin B activity... Delivery Method:
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Xenopus Citation Extract: Dumont J, Umbhauer M, Rassinier P, Hanauer A, Verlhac MH. p90Rsk is not involved in cytostatic factor arrest in mouse oocytes. J Cell Biol. 2005 Apr 25;169(2):227-31. Epub 2005 Apr 18.. |
Pax4 is not essential for beta-cell differentiation in zebrafish embryos but modulates alpha-cell generation by repressing arx gene expression
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Citation:
BMC Dev Biol. 2012;12:37 doi:10.1186/1471-213X-12-37 Epub:
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Background Genetic studies in mouse have demonstrated the crucial function of PAX4 in pancreatic cell differentiation. This... Delivery Method:
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zebrafish Citation Extract: Djiotsa J, Verbruggen V, Giacomotto J, Ishibashi M, Manning E, Rinkwitz S, Manfroid I, LVoz M, Peers B. Pax4 is not essential for beta-cell differentiation in zebrafish embryos but modulates alpha-cell generation by repressing arx gene expression. BMC Dev Biol. 2012;12:37 doi:10.1186/1471-213X-12-37. |