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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12176 scientific papers returned from the database with the search filters currently being used below.

Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip1

Authors:
Lee M, Betz C, Yin J, Paatero I, Schellinx N, Carte AN, Wilson CW, Ye W, Affolter M, Belting HG
Citation:
Development. 2021 Aug 1;148(15):dev197509. doi: 10.1242/dev.197509. Epub 2021 Aug 12. PMID: 34383884; PMCID: PMC8380458
Epub:
Not Epub
Abstract:
Organ morphogenesis is driven by a wealth of tightly orchestrated cellular behaviors, which ensure proper organ assembly and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee M, Betz C, Yin J, Paatero I, Schellinx N, Carte AN, Wilson CW, Ye W, Affolter M, Belting HG. Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip1. Development. 2021 Aug 1;148(15):dev197509. doi: 10.1242/dev.197509. Epub 2021 Aug 12. PMID: 34383884; PMCID: PMC8380458.

The Wnt/PCP formin Daam1 drives cell-cell adhesion during nephron development

Authors:
Krneta-Stankic V, Corkins ME, Paulucci-Holthauzen A, Kloc M, Gladden AB, Miller RK
Citation:
Cell Rep. 2021 Jul 6;36(1):109340. doi: 10.1016/j.celrep.2021.109340. PMID: 34233186; PMCID: PMC8629027
Epub:
Not Epub
Abstract:
E-cadherin junctions facilitate assembly and disassembly of cell contacts that drive development and homeostasis of epithelial...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Krneta-Stankic V, Corkins ME, Paulucci-Holthauzen A, Kloc M, Gladden AB, Miller RK. The Wnt/PCP formin Daam1 drives cell-cell adhesion during nephron development. Cell Rep. 2021 Jul 6;36(1):109340. doi: 10.1016/j.celrep.2021.109340. PMID: 34233186; PMCID: PMC8629027.

Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk

Authors:
Grimm L, Nakajima H, Chaudhury S, Bower NI, Okuda KS, Cox AG, Harvey NL, Koltowska K, Mochizuki N, Hogan BM
Citation:
Elife. 2019 Apr 30;8:e42881. doi: 10.7554/eLife.42881
Epub:
Not Epub
Abstract:
Lymphatic vascular development involves specification of lymphatic endothelial progenitors that subsequently undergo sprouting...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Grimm L, Nakajima H, Chaudhury S, Bower NI, Okuda KS, Cox AG, Harvey NL, Koltowska K, Mochizuki N, Hogan BM. Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk. Elife. 2019 Apr 30;8:e42881. doi: 10.7554/eLife.42881.

Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis

Authors:
Pizzo L, Lasser M, Yusuff T, Jensen M, Ingraham P, Huber E, Singh MD, Monahan C, Iyer J, Desai I, Karthikeyan S, Gould DJ, Yennawar S, Weiner AT, Pounraja VK, Krishnan A, Rolls MM, Lowery LA, Girirajan S
Citation:
PLoS Genet. 2021 Apr 5;17(4):e1009112. doi: 10.1371/journal.pgen.1009112. PMID: 33819264; PMCID: PMC8049494
Epub:
Not Epub
Abstract:
We previously identified a deletion on chromosome 16p12.1 that is mostly inherited and associated with multiple...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pizzo L, Lasser M, Yusuff T, Jensen M, Ingraham P, Huber E, Singh MD, Monahan C, Iyer J, Desai I, Karthikeyan S, Gould DJ, Yennawar S, Weiner AT, Pounraja VK, Krishnan A, Rolls MM, Lowery LA, Girirajan S. Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis. PLoS Genet. 2021 Apr 5;17(4):e1009112. doi: 10.1371/journal.pgen.1009112. PMID: 33819264; PMCID: PMC8049494.

TRIM28 regulates sprouting angiogenesis through VEGFR-DLL4-Notch signaling circuit

Authors:
Wang Y, Singh AR, Zhao Y, Du T, Huang Y, Wan X, Mukhopadhyay D, Wang Y, Wang N, Zhang P
Citation:
FASEB J. 2020 Sep 12. doi: 10.1096/fj.202000186RRR. Online ahead of print
Epub:
Yes
Abstract:
Sprouting angiogenesis is a highly coordinately process controlled by vascular endothelial growth factor receptor (VEGFR)-Notch...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Y, Singh AR, Zhao Y, Du T, Huang Y, Wan X, Mukhopadhyay D, Wang Y, Wang N, Zhang P. TRIM28 regulates sprouting angiogenesis through VEGFR-DLL4-Notch signaling circuit. FASEB J. 2020 Sep 12. doi: 10.1096/fj.202000186RRR. Online ahead of print.

Metformin-induced suppression of NLK improves erythropoiesis in pre-clinical models of Diamond Blackfan Anemia through induction of miR-26a

Authors:
Wilkes MC, Siva K, Varetti G, Mercado J, Wentworth EP, Perez C, Saxena M, Kam S, Kapur S, Chen J, Narla A, Glader B, Lin S, Serrano M, Flygare J, Sakamoto KM
Citation:
Exp Hematol. 2020 Sep 11:S0301-472X(20)30552-X. doi: 10.1016/j.exphem.2020.09.187. Online ahead of print
Epub:
Not Epub
Abstract:
Diamond Blackfan Anemia (DBA) results from haploinsufficiency of ribosomal protein subunits in hematopoietic progenitors in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wilkes MC, Siva K, Varetti G, Mercado J, Wentworth EP, Perez C, Saxena M, Kam S, Kapur S, Chen J, Narla A, Glader B, Lin S, Serrano M, Flygare J, Sakamoto KM. Metformin-induced suppression of NLK improves erythropoiesis in pre-clinical models of Diamond Blackfan Anemia through induction of miR-26a. Exp Hematol. 2020 Sep 11:S0301-472X(20)30552-X. doi: 10.1016/j.exphem.2020.09.187. Online ahead of print.

Transgenerational inheritance of impaired larval T cell development in zebrafish

Authors:
Iwanami N, Lawir DF, Sikora K, O Meara C, Takeshita K, Schorpp M, Boehm T
Citation:
Nat Commun. 2020 Sep 9;11(1):4505. doi: 10.1038/s41467-020-18289-9
Epub:
Not Epub
Abstract:
Evidence for transgenerational inheritance of epigenetic information in vertebrates is scarce. Aberrant patterns of DNA...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Iwanami N, Lawir DF, Sikora K, O Meara C, Takeshita K, Schorpp M, Boehm T. Transgenerational inheritance of impaired larval T cell development in zebrafish. Nat Commun. 2020 Sep 9;11(1):4505. doi: 10.1038/s41467-020-18289-9.

A Mutation in VWA1, Encoding von Willebrand Factor A Domain-Containing Protein 1, Is Associated With Hemifacial Microsomia

Authors:
Yibei W, Lu P, Xiaodong L, Yushan C, Xinmiao F, Lianyan L, Yaping L, Pu W, Shuyang Z, Bo Z, Xiaowei C
Citation:
Front Cell Dev Biol. 2020;8:922. doi:10.3389/fcell.2020.571004
Epub:
Not Epub
Abstract:
Background: Hemifacial microsomia (HFM) is a type of rare congenital syndrome caused by developmental disorders of the first...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yibei W, Lu P, Xiaodong L, Yushan C, Xinmiao F, Lianyan L, Yaping L, Pu W, Shuyang Z, Bo Z, Xiaowei C. A Mutation in VWA1, Encoding von Willebrand Factor A Domain-Containing Protein 1, Is Associated With Hemifacial Microsomia. Front Cell Dev Biol. 2020;8:922. doi:10.3389/fcell.2020.571004.

Fibrodysplasia ossificans progressiva mutant ACVR1 signals by multiple modalities in the developing zebrafish

Authors:
Allen RS, Tajer B, Shore EM, Mullins MC
Citation:
Elife. 2020 Sep 8;9:e53761. doi: 10.7554/eLife.53761
Epub:
Not Epub
Abstract:
Fibrodysplasia ossificans progressiva (FOP) is a rare human genetic disorder characterized by altered skeletal development and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Allen RS, Tajer B, Shore EM, Mullins MC. Fibrodysplasia ossificans progressiva mutant ACVR1 signals by multiple modalities in the developing zebrafish. Elife. 2020 Sep 8;9:e53761. doi: 10.7554/eLife.53761.

The single nucleotide variant at c.662A>G in human RRM2B is a loss-of-function mutation

Authors:
Tseng YT, Li SW, HuangFu WC, Yen Y, Liu IH
Citation:
Mol Genet Genomic Med. 2020 Sep 15:e1497. doi: 10.1002/mgg3.1497. Online ahead of print
Epub:
Not Epub
Abstract:
Background: Mitochondrial DNA maintenance defects (MDMDs) is one of the critical pediatric dysfunction. One of the recent...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tseng YT, Li SW, HuangFu WC, Yen Y, Liu IH. The single nucleotide variant at c.662A>G in human RRM2B is a loss-of-function mutation. Mol Genet Genomic Med. 2020 Sep 15:e1497. doi: 10.1002/mgg3.1497. Online ahead of print.

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