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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12176 scientific papers returned from the database with the search filters currently being used below.
There are 12176 scientific papers returned from the database with the search filters currently being used below.
Physiology and morphological correlates of excitatory transmission are preserved in glutamine transporter SN1- depleted mouse frontal cortex
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Citation:
Neurosci. 2020;[Epub] doi:10.1016/j.neuroscience.2020.08.019 Epub:
Not Epub Abstract:
Glutamine is an astroglia-derived precursor of the neurotransmitter glutamate, and its astroglia-to-neuron transfer is... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Popek M, Bobula B, Sowa J, Hess G, Frontczak-Baniewicz M, Albrecht J, Zielińska M. Physiology and morphological correlates of excitatory transmission are preserved in glutamine transporter SN1- depleted mouse frontal cortex. Neurosci. 2020;[Epub] doi:10.1016/j.neuroscience.2020.08.019. |
Llgl1 regulates zebrafish cardiac development by mediating Yap stability in cardiomyocytes
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Citation:
Development. 2020 Aug 25;147(16):dev193581. doi: 10.1242/dev.193581 Epub:
Not Epub Abstract:
The Hippo-Yap pathway regulates multiple cellular processes in response to mechanical and other stimuli. In Drosophila, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Flinn MA, Otten C, Brandt ZJ, Bostrom JR, Kenarsary A, Wan TC, Auchampach JA, Abdelilah-Seyfried S, O'Meara CC, Link BA. Llgl1 regulates zebrafish cardiac development by mediating Yap stability in cardiomyocytes. Development. 2020 Aug 25;147(16):dev193581. doi: 10.1242/dev.193581. |
BVES downregulation in non-syndromic tetralogy of fallot is associated with ventricular outflow tract stenosis
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Citation:
Sci Rep. 2020:(10)1:14167. doi:10.1038/s41598-020-70806-4 Epub:
Not Epub Abstract:
BVES is a transmembrane protein, our previous work demonstrated that single nucleotide mutations of BVES in tetralogy of fallot... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shi Y, Li Y, Wang Y, Zhu P, Chen Y, Wang H, Yue S, Xia X, Chen J, Jiang Z, Zhou C, Cai W, Yuan H, Wu Y, Wan Y, Li X, Zhu X, Zhou Z, Dai G, Li F, Mo X, Ye X, Fan X, Zhuang J, Wu X, Yuan W. BVES downregulation in non-syndromic tetralogy of fallot is associated with ventricular outflow tract stenosis. Sci Rep. 2020:(10)1:14167. doi:10.1038/s41598-020-70806-4. |
Selective dephosphorylation by PP2A-B55 directs the meiosis I-meiosis II transition in oocytes
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Citation:
Elife. 2021 Aug 3;10:e70588. doi: 10.7554/eLife.70588. PMID: 34342579; PMCID: PMC8370769 Epub:
Not Epub Abstract:
Meiosis is a specialized cell cycle that requires sequential changes to the cell division machinery to facilitate changing... Delivery Method:
microinjection Organism or Cell Type:
Patiria miniata (sea star) Citation Extract: Swartz SZ, Nguyen HT, McEwan BC, Adamo ME, Cheeseman IM, Kettenbach AN. Selective dephosphorylation by PP2A-B55 directs the meiosis I-meiosis II transition in oocytes. Elife. 2021 Aug 3;10:e70588. doi: 10.7554/eLife.70588. PMID: 34342579; PMCID: PMC8370769. |
The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish
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Citation:
BMC Biol. 2024 Feb 27;22(1):51. doi: 10.1186/s12915-024-01850-z. PMID: 38414014; PMCID: PMC10900589 Epub:
Not Epub Abstract:
Background: Lymphangiogenesis, the formation of lymphatic vessels, is tightly linked to the development of the venous... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Veloso A, Bleuart A, Conrard L, Orban T, Bruyr J, Cabochette P, Germano RFV, Schevenels G, Bernard A, Zindy E, Demeyer S, Vanhollebeke B, Dequiedt F, Martin M. The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish. BMC Biol. 2024 Feb 27;22(1):51. doi: 10.1186/s12915-024-01850-z. PMID: 38414014; PMCID: PMC10900589. |
Exploration and optimization of processes for key intermediates of phosphorodiamidate morpholino oligonucleotides.
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Citation:
Military Medical Sciences. 2017;41(8):662-666 (Chinese) Epub:
Not Epub Abstract:
Objective: To explore and optimize the processes for synthesis of key intermediates of phosphorodiamidate morpholino... Citation Extract: Chen RX, Guo JY, Song BY, Zhang ND, Xu KL, Wang GB, Dou YY, Wang QH. Exploration and optimization of processes for key intermediates of phosphorodiamidate morpholino oligonucleotides.. Military Medical Sciences. 2017;41(8):662-666 (Chinese). |
Skipping Exon-v6 from CD44v6-Containing Isoforms Influences Chemotherapy Response and Self-Renewal Capacity of Gastric Cancer Cells
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Citation:
Cancers. 2020;12(9):2072-6694 doi:10.3390/cancers12092378 Epub:
Not Epub Abstract:
De novo expressed CD44 isoforms containing exon-v6 are frequently associated with gastric cancer (GC) aggressiveness, and may... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human gastric cancer, MKN45 & GP202 Citation Extract: Lobo S, Pereira C, Oliveira C, Almeida GM. Skipping Exon-v6 from CD44v6-Containing Isoforms Influences Chemotherapy Response and Self-Renewal Capacity of Gastric Cancer Cells. Cancers. 2020;12(9):2072-6694 doi:10.3390/cancers12092378. |
Expression of acid-labile subunit (als) in developing and adult zebrafish and its role in dorso-ventral patterning during development
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Citation:
Gen Comp Endocrinol. 2020 Aug 20:113591. doi:10.1016/j.ygcen.2020.113591. Online ahead of print Epub:
Yes Abstract:
Mammalian acid-labile subunit (ALS) is a serum protein that binds binary complexes between Insulin-like growth factors (IGFs)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Landi E, Karabatas L, Scaglia P, Pisciottano F, Gutierrez M, Ramirez L, Bergadá I, Rey R, Guillermo Jasper H, Mario Domené H, Viviana Plazas P, Domené S. Expression of acid-labile subunit (als) in developing and adult zebrafish and its role in dorso-ventral patterning during development. Gen Comp Endocrinol. 2020 Aug 20:113591. doi:10.1016/j.ygcen.2020.113591. Online ahead of print. |
Morpholino Oligomer-Induced Dystrophin Isoforms to Map the Functional Domains in the Dystrophin Protein
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Citation:
Molec Ther. 2020 Aug 21;22:263-272. doi:10.1016/j.omtn.2020.08.019 Epub:
Not Epub Abstract:
Dystrophin plays a crucial role in maintaining sarcolemma stability during muscle contractions, and mutations that prevent the... Delivery Method:
(RxR)4 peptide-linked; intraperitoneal (i.p.) Organism or Cell Type:
cell culture: murine H2K mdx myogenic cells; mice: mdx & C57BL/10ScSn Citation Extract: Li D, Adams AM, Johnsen RD, Fletcher S, Wilton SD. Morpholino Oligomer-Induced Dystrophin Isoforms to Map the Functional Domains in the Dystrophin Protein. Molec Ther. 2020 Aug 21;22:263-272. doi:10.1016/j.omtn.2020.08.019. |
Paired Box 9 (PAX9), the RNA polymerase II transcription factor, regulates human ribosome biogenesis and craniofacial development
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Citation:
PLoS Genet. 2020;16(8):e1008967. doi:10.1371/journal.pgen.1008967 Epub:
Not Epub Abstract:
Dysregulation of ribosome production can lead to a number of developmental disorders called ribosomopathies. Despite the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Farley-Barnes KI, Deniz E, Overton MM, Khokha MK, Baserga SJ. Paired Box 9 (PAX9), the RNA polymerase II transcription factor, regulates human ribosome biogenesis and craniofacial development. PLoS Genet. 2020;16(8):e1008967. doi:10.1371/journal.pgen.1008967. |