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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Gtpbp2 is a positive regulator of Wnt signaling and maintains low levels of the Wnt negative regulator Axin
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Citation:
Cell Commun Signal. 2016 Aug 2;14(1):15. doi: 10.1186/s12964-016-0138-x Epub:
Not Epub Abstract:
BACKGROUND: Canonical Wnt signals, transduced by stabilized β-catenin, play similar roles across animals in maintaining stem... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Gillis WQ, Kirmizitas A, Iwasaki Y, Ki DH, Wyrick JM, Thomsen GH. Gtpbp2 is a positive regulator of Wnt signaling and maintains low levels of the Wnt negative regulator Axin. Cell Commun Signal. 2016 Aug 2;14(1):15. doi: 10.1186/s12964-016-0138-x. |
Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells
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Citation:
Dev Cell. 2016 Aug 3. pii: S1534-5807(16)30427-0. doi: 10.1016/j.devcel.2016.06.024. [Epub ahead of print] Epub:
Yes Abstract:
Hematopoietic stem cells (HSCs) are self-renewing multipotent stem cells that generate mature blood lineages throughout life.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Monteiro R, Pinheiro P, Joseph N, Peterkin T, Koth J, Repapi E, Bonkhofer F, Kirmizitas A, Patient R. Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells. Dev Cell. 2016 Aug 3. pii: S1534-5807(16)30427-0. doi: 10.1016/j.devcel.2016.06.024. [Epub ahead of print]. |
A recurring mutation in the respiratory complex 1 protein NDUFB11 is responsible for a novel form of X-linked sideroblastic anemia
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Citation:
Blood. 2016 Aug 3. pii: blood-2016-05-719062. [Epub ahead of print] Epub:
Yes Abstract:
The congenital sideroblastic anemias (CSAs) are a heterogeneous group of inherited blood disorders characterized by... Citation Extract: Lichtenstein DA, Crispin AW, Sendamarai AK, Campagna DR, Schmitz-Abe K, Sousa CM, Kafina MD, Schmidt PJ, Niemeyer CM, Porter J, May A, Patnaik MM, Heeney MM, Kimmelman A, Bottomley SS, Paw BH, Markianos K, Fleming MD. A recurring mutation in the respiratory complex 1 protein NDUFB11 is responsible for a novel form of X-linked sideroblastic anemia. Blood. 2016 Aug 3. pii: blood-2016-05-719062. [Epub ahead of print]. |
Investigating Synthetic Oligonucleotide Targeting of Mir31 in Duchenne Muscular Dystrophy
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Citation:
PLoS Curr. 2016 Jun 16;8. pii: ecurrents.md.99d88e72634387639707601b237467d7. doi: 10.1371/currents.md.99d88e72634387639707601b237467d7 Epub:
Not Epub Abstract:
Exon-skipping via synthetic antisense oligonucleotides represents one of the most promising potential therapies for Duchenne... Delivery Method:
electroporation, cell bathing, Vivo-Morpholino Organism or Cell Type:
cell culture: H2KSF1 (derived from an mdx-immortomouse cross), mdx mice Citation Extract: Hildyard JC, Wells DJ. Investigating Synthetic Oligonucleotide Targeting of Mir31 in Duchenne Muscular Dystrophy. PLoS Curr. 2016 Jun 16;8. pii: ecurrents.md.99d88e72634387639707601b237467d7. doi: 10.1371/currents.md.99d88e72634387639707601b237467d7. |
HER2-positive breast cancer targeting and treatment by a peptide-conjugated mini nanodrug
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Citation:
Nanomedicine. 2016 Aug 9. pii: S1549-9634(16)30103-4. doi: 10.1016/j.nano.2016.07.013. [Epub ahead of print] Epub:
Yes Abstract:
HER2+ breast cancer is one of the most aggressive forms of breast cancer. The new polymalic acid-based mini nanodrug copolymers... Delivery Method:
nanoparticle Organism or Cell Type:
cell culture: BT474 human breast cancer, MDA-MB-468, mice Citation Extract: Ding H, Gangalum PR, Galstyan A, Fox I, Patil R, Hubbard P, Murali R, Ljubimova JY, Holler E. HER2-positive breast cancer targeting and treatment by a peptide-conjugated mini nanodrug. Nanomedicine. 2016 Aug 9. pii: S1549-9634(16)30103-4. doi: 10.1016/j.nano.2016.07.013. [Epub ahead of print]. |
Vitamin D receptor deficiency impairs inner ear development in zebrafish
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Citation:
Biochem Biophys Res Commun. 2016 Aug 12. pii: S0006-291X(16)31325-0. doi: 10.1016/j.bbrc.2016.08.070. [Epub ahead of print] Epub:
Yes Abstract:
The biological actions of vitamin D are largely mediated through binding to the vitamin D receptor (VDR), a member of the... Organism or Cell Type:
zebrafish Citation Extract: Kwon HJ. Vitamin D receptor deficiency impairs inner ear development in zebrafish. Biochem Biophys Res Commun. 2016 Aug 12. pii: S0006-291X(16)31325-0. doi: 10.1016/j.bbrc.2016.08.070. [Epub ahead of print]. |
Zebrafish P54 RNA helicases are cytoplasmic granules residents that are required for development and stress resilience
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Citation:
Biol Open. 2016 Aug 3. pii: bio.015826. doi: 10.1242/bio.015826. [Epub ahead of print] Epub:
Yes Abstract:
Stress granules are cytoplasmic foci that directly respond to the protein synthesis status of the cell. Various environmental... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zampedri C, Tinoco-Cuellar M, Carrillo-Rosas S, Diaz-Tellez A, Ramos-Balderas JL, Pelegri F, Maldonado E. Zebrafish P54 RNA helicases are cytoplasmic granules residents that are required for development and stress resilience. Biol Open. 2016 Aug 3. pii: bio.015826. doi: 10.1242/bio.015826. [Epub ahead of print]. |
Wtip is required for proepicardial organ specification and cardiac left/right asymmetry in zebrafish
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Citation:
Mol Med Rep. 2016 Sep;14(3):2665-78. doi: 10.3892/mmr.2016.5550. Epub 2016 Jul 27 Epub:
Not Epub Abstract:
Wilm's tumor 1 interacting protein (Wtip) was identified as an interacting partner of Wilm's tumor protein (WT1) in a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Powell R, Bubenshchikova E, Fukuyo Y, Hsu C, Lakiza O, Nomura H, Renfrew E, Garrity D, Obara T. Wtip is required for proepicardial organ specification and cardiac left/right asymmetry in zebrafish. Mol Med Rep. 2016 Sep;14(3):2665-78. doi: 10.3892/mmr.2016.5550. Epub 2016 Jul 27. |
Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway
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Citation:
J Biomed Sci. 2016 Aug 2;23(1):59. doi: 10.1186/s12929-016-0277-9 Epub:
Not Epub Abstract:
BACKGROUND: Development of neural and vascular systems displays astonishing similarities among vertebrates. This parallelism is... Organism or Cell Type:
zebrafish Citation Extract: Liu LY, Lin MH, Lai ZY, Jiang JP, Huang YC, Jao LE, Chuang YJ. Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway. J Biomed Sci. 2016 Aug 2;23(1):59. doi: 10.1186/s12929-016-0277-9. |
An amphipathic trans-acting phosphorothioate DNA element delivers uncharged PNA and PMO nucleic acid sequences in mammalian cells
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Citation:
Curr Protoc Nucleic Acid Chem. 2016;64:4.69.1-4.69.22. Epub 2016 Mar 1 Epub:
Not Epub Abstract:
An innovative approach to the delivery of uncharged peptide nucleic acids (PNAs) and phosphorodiamidate morpholino (PMO)... Organism or Cell Type:
cell culture: HeLa pLuc705 Citation Extract: Jain HV, Beaucage SL. An amphipathic trans-acting phosphorothioate DNA element delivers uncharged PNA and PMO nucleic acid sequences in mammalian cells. Curr Protoc Nucleic Acid Chem. 2016;64:4.69.1-4.69.22. Epub 2016 Mar 1. |