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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Discovery, Synthesis, and Optimization of Diarylisoxazole-3-carboxamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore
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Citation:
ChemMedChem. 2015 Oct;10(10):1655-71. doi: 10.1002/cmdc.201500284. Epub 2015 Aug 18 Epub:
Not Epub Abstract:
The mitochondrial permeability transition pore (mtPTP) is a Ca2+-requiring mega-channel which, under pathological conditions,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Roy S, Šileikytė J, Schiavone M, Neuenswander B, Argenton F, Aubé J, Hedrick MP, Chung TD, Forte MA, Bernardi P, Schoenen FJ. Discovery, Synthesis, and Optimization of Diarylisoxazole-3-carboxamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore. ChemMedChem. 2015 Oct;10(10):1655-71. doi: 10.1002/cmdc.201500284. Epub 2015 Aug 18. |
A susceptibility locus rs7099208 is associated with non-obstructive azoospermia via reduction in the expression of FAM160B1
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Citation:
J Biomed Res. 2015 Nov;29(6):491-500. doi: 10.7555/JBR.29.20150034. Epub 2015 Aug 8. Erratum in: J Biomed Res. 2015 Nov;29(6):518 Epub:
Not Epub Abstract:
Non-obstructive azoospermia (NOA) is a severe defect in male reproductive health that occurs in 1% of adult men. In a previous... Organism or Cell Type:
cell culture: mouse spermatocyte GC2-spd Citation Extract: Zhang Y, Qian J, Wu M, Liu M, Zhang K, Lin Y, Guo X, Zhou Z, Hu Z, Sha J. A susceptibility locus rs7099208 is associated with non-obstructive azoospermia via reduction in the expression of FAM160B1. J Biomed Res. 2015 Nov;29(6):491-500. doi: 10.7555/JBR.29.20150034. Epub 2015 Aug 8. Erratum in: J Biomed Res. 2015 Nov;29(6):518. |
ZBTB42 mutation defines a novel lethal congenital contracture syndrome (LCCS6)
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Citation:
Hum Mol Genet. 2014 Dec 15;23(24):6584-93. doi: 10.1093/hmg/ddu384. Epub 2014 Jul 23 Epub:
Not Epub Abstract:
Lethal congenital contracture syndrome (LCCS) is a lethal autosomal recessive form of arthrogryposis multiplex congenita (AMC... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Patel N, Smith LL, Faqeih E, Mohamed J, Gupta VA, Alkuraya FS. ZBTB42 mutation defines a novel lethal congenital contracture syndrome (LCCS6). Hum Mol Genet. 2014 Dec 15;23(24):6584-93. doi: 10.1093/hmg/ddu384. Epub 2014 Jul 23. |
The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway
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Citation:
J Biol Chem. 2015 Dec 18;290(51):30562-72. doi: 10.1074/jbc.M115.697615. Epub 2015 Oct 23 Epub:
Not Epub Abstract:
The non-canonical WNT/planar cell polarity (WNT/PCP) pathway plays important roles in morphogenetic processes in vertebrates.... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Martinez S, Scerbo P, Giordano M, Daulat AM, Lhoumeau AC, Thomé V, Kodjabachian L, Borg JP. The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway. J Biol Chem. 2015 Dec 18;290(51):30562-72. doi: 10.1074/jbc.M115.697615. Epub 2015 Oct 23. |
Safety and pharmacokinetic profile of eteplirsen, SRP-4045, and SRP-4053, three phosphorodiamidate morpholino oligomers (PMOs) for the treatment of patients with Duchenne muscular dystrophy (DMD)
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Citation:
Neuromusc Dis. 2014. 24(9-10):828. doi:10.1016/j.nmd.2014.06.124 Epub:
Not Epub Abstract:
Eteplirsen, SRP-4045 and SRP-4053 are three PMOs developed as treatments for DMD. DMD is mostly caused by mutations in the... Delivery Method:
iv infusion Organism or Cell Type:
Nonhuman primate, human Citation Extract: Sazani P, Magee T, Charleston JS, Shanks C, Zhang J, Carver M, Rodino-Klapac L, Sahenk Z, Roush K, Bird L, Lowes LP, Alfano L, Gomez AM, Lewis S, Malik V, Shontz K, Flanigan K, Shilling C, Bhalli J, Kaur H, Walisser J, Forget J, Saoud J, Mendell JR, Kaye E
. Safety and pharmacokinetic profile of eteplirsen, SRP-4045, and SRP-4053, three phosphorodiamidate morpholino oligomers (PMOs) for the treatment of patients with Duchenne muscular dystrophy (DMD). Neuromusc Dis. 2014. 24(9-10):828. doi:10.1016/j.nmd.2014.06.124. |
Venous-derived angioblasts generate organ-specific vessels during zebrafish embryonic development
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Citation:
Development. 2015 Dec 15;142(24):4266-78. doi: 10.1242/dev.129247. Epub 2015 Nov 2 Epub:
Not Epub Abstract:
Formation and remodeling of vascular beds are complex processes orchestrated by multiple signaling pathways. Although it is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hen G, Nicenboim J, Mayseless O, Asaf L, Shin M, Busolin G, Hofi R, Almog G, Tiso N, Lawson ND, Yaniv K. Venous-derived angioblasts generate organ-specific vessels during zebrafish embryonic development. Development. 2015 Dec 15;142(24):4266-78. doi: 10.1242/dev.129247. Epub 2015 Nov 2. |
Asymmetric cell convergence-driven zebrafish fin bud initiation and pre-pattern requires Tbx5a control of a mesenchymal Fgf signal
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Citation:
Development. 2015 Dec 15;142(24):4329-39. doi: 10.1242/dev.124750. Epub 2015 Nov 2 Epub:
Not Epub Abstract:
Tbx5 plays a pivotal role in vertebrate forelimb initiation, and loss-of-function experiments result in deformed or absent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mao Q, Stinnett HK, Ho RK. Asymmetric cell convergence-driven zebrafish fin bud initiation and pre-pattern requires Tbx5a control of a mesenchymal Fgf signal. Development. 2015 Dec 15;142(24):4329-39. doi: 10.1242/dev.124750. Epub 2015 Nov 2. |
Two-Pore Channel 2 activity is required for slow muscle cell-generated Ca 2+signaling during myogenesis in intact zebrafish
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Citation:
Int J Dev Biol. 2015;59(7-8-9):313-325 Epub:
Not Epub Abstract:
We have recently characterized essential inositol 1,4,5-trisphosphate receptor (IP 3R) and ryanodine receptor (RyR)-mediated Ca... Organism or Cell Type:
zebrafish Citation Extract: Kelu JJ, Chan HL, Webb SE, Cheng AH, Ruas M, Parrington J, Galione A, Miller AL. Two-Pore Channel 2 activity is required for slow muscle cell-generated Ca 2+signaling during myogenesis in intact zebrafish. Int J Dev Biol. 2015;59(7-8-9):313-325. |
Cortisol regulates sodium homeostasis by stimulating the transcription of sodium-chloride transporter (NCC) in zebrafish (Danio rerio)
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Citation:
Mol Cell Endocrinol. 2015 Dec 8. pii: S0303-7207(15)30156-8. doi: 10.1016/j.mce.2015.12.001. [Epub ahead of print] Epub:
Yes Abstract:
In mammals, sodium/hydrogen exchanger (NHE) and sodium-chloride cotransporter (NCC) are expressed in renal tubules, and exhibit... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin CH, Hu HJ, Hwang PP. Cortisol regulates sodium homeostasis by stimulating the transcription of sodium-chloride transporter (NCC) in zebrafish (Danio rerio). Mol Cell Endocrinol. 2015 Dec 8. pii: S0303-7207(15)30156-8. doi: 10.1016/j.mce.2015.12.001. [Epub ahead of print]. |
Suppression of vascular network formation by chronic hypoxia and prolyl-hydroxylase 2 (phd2) deficiency during vertebrate development
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Citation:
Angiogenesis. 2015 Dec 17. [Epub ahead of print] doi:10.1007/s10456-015-9492-3 Epub:
Yes Abstract:
In the adult, new vessels and red blood cells form in response to hypoxia. Here, the oxygen-sensing system (PHD-HIF) has... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Metikala S, Neuhaus H, Hollemann T. Suppression of vascular network formation by chronic hypoxia and prolyl-hydroxylase 2 (phd2) deficiency during vertebrate development. Angiogenesis. 2015 Dec 17. [Epub ahead of print] doi:10.1007/s10456-015-9492-3. |