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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells
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Citation:
J Cell Biol. 2015;211(5):964-73. doi:10.1083/jcb.201502043 Epub:
Not Epub Abstract:
Motile cilia polarization requires intracellular anchorage to the cytoskeleton; however, the molecular machinery that supports... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Yasunaga T, Hoff S, Schell C, Helmstädter M, Kretz O, Kuechlin S, Yakulov TA, Engel C, Müller B, Bensch R, Ronneberger O, Huber TB, Lienkamp SS, Walz G. The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells. J Cell Biol. 2015;211(5):964-73. doi:10.1083/jcb.201502043. |
Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type
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Citation:
Am J Hum Gen. 2015;97(6):790-800. doi:10.1016/j.ajhg.2015.10.014 Epub:
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Circumferential skin creases Kunze type (CSC-KT) is a specific congenital entity with an unknown genetic cause. The disease... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Isrie M, Breuss M, Tian G, Hansen AH, Cristofoli F, Morandell J, Kupchinsky ZA, Sifrim A, Rodriguez-Rodriguez CM, Dapena EP, Doonanco K, Leonard N, Tinsa F, Moortgat S, Ulucan H, Koparir E, Karaca E, Katsanis N, Marton V, Vermeesch JR, Davis EE, Cowan NJ, Keays DA, Van Esch H. Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type. Am J Hum Gen. 2015;97(6):790-800. doi:10.1016/j.ajhg.2015.10.014. |
PRMT8 as a phospholipase regulates Purkinje cell dendritic arborization and motor coordination
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Citation:
Sci Adv. 2015;1:e1500615 doi:10.1126/sciadv.1500615 Epub:
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The development of vertebrate neurons requires a change in membrane phosphatidylcholine (PC) metabolism. Although PC hydrolysis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kim J-D, Park KE, Ishida J, Kako K, Hamada J, Kani S, Takeuchi M, Namiki K, Fukui H, Fukuhara S, Hibi M, Kobayashi M, Kanaho Y, Kasuya Y, Mochizuki N, Fukamizu A. PRMT8 as a phospholipase regulates Purkinje cell dendritic arborization and motor coordination. Sci Adv. 2015;1:e1500615 doi:10.1126/sciadv.1500615. |
Cortisol Regulates Acid Secretion of H+-ATPase-rich Ionocytes in Zebrafish (Danio rerio) Embryos
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Citation:
Front Physiol. 2015 Nov 17;6:328. eCollection 2015 Epub:
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Systemic acid-base regulation is vital for physiological processes in vertebrates. Freshwater (FW) fish live in an inconstant... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin CH, Shih TH, Liu ST, Hsu HH, Hwang PP. Cortisol Regulates Acid Secretion of H+-ATPase-rich Ionocytes in Zebrafish (Danio rerio) Embryos. Front Physiol. 2015 Nov 17;6:328. eCollection 2015. |
Zebrafish diras1 Promoted Neurite Outgrowth in Neuro-2a Cells and Maintained Trigeminal Ganglion Neurons In Vivo via Rac1-Dependent Pathway
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Citation:
Mol Neurobiol. 2015 Dec 3. [Epub ahead of print] Epub:
Yes Abstract:
The small GTPase Ras superfamily regulates several neuronal functions including neurite outgrowth and neuron proliferation. In... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yeh CW, Hsu LS. Zebrafish diras1 Promoted Neurite Outgrowth in Neuro-2a Cells and Maintained Trigeminal Ganglion Neurons In Vivo via Rac1-Dependent Pathway. Mol Neurobiol. 2015 Dec 3. [Epub ahead of print]. |
A nonsynonymous mutation in the transcriptional regulator lbh is associated with cichlid craniofacial adaptation and neural crest cell development
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Citation:
Mol Biol Evol. 2014 Dec;31(12):3113-24. doi: 10.1093/molbev/msu267. Epub 2014 Sep 18 Epub:
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Since the time of Darwin, biologists have sought to understand the origins and maintenance of life's diversity of form.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Powder KE, Cousin H, McLinden GP, Albertson RC. A nonsynonymous mutation in the transcriptional regulator lbh is associated with cichlid craniofacial adaptation and neural crest cell development. Mol Biol Evol. 2014 Dec;31(12):3113-24. doi: 10.1093/molbev/msu267. Epub 2014 Sep 18. |
Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models
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Citation:
Nat Med. 2015 Jun;21(6):601-9. doi: 10.1038/nm.3843. Epub 2015 May 11 Epub:
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Dysregulation of the actin cytoskeleton in podocytes represents a common pathway in the pathogenesis of proteinuria across a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Schiffer M, Teng B, Gu C, Shchedrina VA, Kasaikina M, Pham VA, Hanke N, Rong S, Gueler F, Schroder P, Tossidou I, Park JK, Staggs L, Haller H, Erschow S, Hilfiker-Kleiner D, Wei C, Chen C, Tardi N, Hakroush S, Selig MK, Vasilyev A, Merscher S, Reiser J, Sever S. Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models. Nat Med. 2015 Jun;21(6):601-9. doi: 10.1038/nm.3843. Epub 2015 May 11. |
Tumor cell-targeted delivery of nanoconjugated oligonucleotides in composite spheroids
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Citation:
Nucleic Acid Ther. 2014 Dec;24(6):413-9. doi: 10.1089/nat.2014.0493 Epub:
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Standard tissue culture has often been a poor model for predicting the efficacy of anti-cancer agents including... Delivery Method:
nanoparticle Organism or Cell Type:
cell culture: A375 human melanoma, human dermal fibroblasts, multicellular tumor spheroids (MCTS) Citation Extract: Carver K, Ming X, Juliano RL. Tumor cell-targeted delivery of nanoconjugated oligonucleotides in composite spheroids. Nucleic Acid Ther. 2014 Dec;24(6):413-9. doi: 10.1089/nat.2014.0493. |
Elusive sources of variability of dystrophin rescue by exon skipping
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Citation:
Skelet Muscle. 2015 Dec 1;5:44. eCollection 2015 Epub:
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BACKGROUND: Systemic delivery of anti-sense oligonucleotides to Duchenne muscular dystrophy (DMD) patients to induce de novo... Delivery Method:
injection iv retro-orbital Organism or Cell Type:
mice, mdx Citation Extract: Vila MC, Klimek MB, Novak JS, Rayavarapu S, Uaesoontrachoon K, Boehler JF, Fiorillo AA, Hogarth MW, Zhang A, Shaughnessy C, Gordish-Dressman H, Burki U, Straub V, Lu QL, Partridge TA, Brown KJ, Hathout Y, van den Anker J, Hoffman EP, Nagaraju K. Elusive sources of variability of dystrophin rescue by exon skipping. Skelet Muscle. 2015 Dec 1;5:44. eCollection 2015. |
Loss of function of myosin chaperones triggers Hsf1-mediated transcriptional response in skeletal muscle cells
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Citation:
Genome Biol. 2015;16:267 doi:10.1186/s13059-015-0825-8 Epub:
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Background: Mutations in myosin chaperones Unc45b and Hsp90aa1.1 as well as in the Unc45b-binding protein Smyd1b impair... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Etard C, Armant O, Roostalu U, Gourain V, Ferg M, Strähle U. Loss of function of myosin chaperones triggers Hsf1-mediated transcriptional response in skeletal muscle cells. Genome Biol. 2015;16:267 doi:10.1186/s13059-015-0825-8. |