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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Heme-mediated inhibition of Bach1 regulates the liver specificity and transience of the Nrf2-dependent induction of zebrafish heme oxygenase 1

Authors:
Fuse Y, Nakajima H, Nakajima-Takagi Y, Nakajima O, Kobayashi M
Citation:
Genes Cells. 2015 May 18. doi: 10.1111/gtc.12249. [Epub ahead of print]
Epub:
Yes
Abstract:
The induction of the gene encoding heme oxygenase 1 (Hmox1, HO-1) by Nrf2 is unique compared with other Nrf2 targets. We...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fuse Y, Nakajima H, Nakajima-Takagi Y, Nakajima O, Kobayashi M. Heme-mediated inhibition of Bach1 regulates the liver specificity and transience of the Nrf2-dependent induction of zebrafish heme oxygenase 1. Genes Cells. 2015 May 18. doi: 10.1111/gtc.12249. [Epub ahead of print].

Ribonuclease like 5 regulates zebrafish yolk extension by suppressing a p53-dependent DNA damage response pathway

Authors:
Zhai Y, Zhao X, Sheng J, Gao X, Ou Z, Xu Z
Citation:
Int J Biochem Cell Biol. 2015 May 14. pii: S1357-2725(15)00125-9. doi: 10.1016/j.biocel.2015.05.004. [Epub ahead of print]
Epub:
Yes
Abstract:
Ribonuclease like 5 (Rnasel5) is a novel member of the zebrafish ribonuclease A family and its expression is increased during...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhai Y, Zhao X, Sheng J, Gao X, Ou Z, Xu Z. Ribonuclease like 5 regulates zebrafish yolk extension by suppressing a p53-dependent DNA damage response pathway. Int J Biochem Cell Biol. 2015 May 14. pii: S1357-2725(15)00125-9. doi: 10.1016/j.biocel.2015.05.004. [Epub ahead of print].

Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome

Authors:
Guemez-Gamboa A, Nguyen LN, Yang H, Zaki MS, Kara M, Ben-Omran T, Akizu N, Rosti RO, Rosti B, Scott E, Schroth J, Copeland B, Vaux KK, Cazenave-Gassiot A, Quek DQ, Wong BH, Tan BC, Wenk MR, Gunel M, Gabriel S, Chi NC, Silver DL, Gleeson JG
Citation:
Nat Genet. 2015 May 25. doi: 10.1038/ng.3311. [Epub ahead of print]
Epub:
Yes
Abstract:
Docosahexanoic acid (DHA) is the most abundant omega-3 fatty acid in brain, and, although it is considered essential,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guemez-Gamboa A, Nguyen LN, Yang H, Zaki MS, Kara M, Ben-Omran T, Akizu N, Rosti RO, Rosti B, Scott E, Schroth J, Copeland B, Vaux KK, Cazenave-Gassiot A, Quek DQ, Wong BH, Tan BC, Wenk MR, Gunel M, Gabriel S, Chi NC, Silver DL, Gleeson JG. Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome. Nat Genet. 2015 May 25. doi: 10.1038/ng.3311. [Epub ahead of print].

Induction of Phosphoenolpyruvate Carboxykinase (PEPCK) during Acute Acidosis and Its Role in Acid Secretion by V-ATPase-Expressing Ionocytes

Authors:
Furukawa F, Tseng YC, Liu ST, Chou YL, Lin CC, Sung PH, Uchida K, Lin LY, Hwang PP
Citation:
Int J Biol Sci. 2015 May 1;11(6):712-725. eCollection 2015
Epub:
Not Epub
Abstract:
Vacuolar-Type H+-ATPase (V-ATPase) takes the central role in pumping H+ through cell membranes of diverse organisms, which is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Furukawa F, Tseng YC, Liu ST, Chou YL, Lin CC, Sung PH, Uchida K, Lin LY, Hwang PP. Induction of Phosphoenolpyruvate Carboxykinase (PEPCK) during Acute Acidosis and Its Role in Acid Secretion by V-ATPase-Expressing Ionocytes. Int J Biol Sci. 2015 May 1;11(6):712-725. eCollection 2015.

Functional analysis of hairy genes in Xenopus neural crest initial specification and cell migration

Authors:
Vega-López GA, Bonano M, Tríbulo C, Fernández JP, Agüero TH, Aybar MJ
Citation:
Dev Dyn. 2015 May 22. doi: 10.1002/dvdy.24295. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Neural crest formation is one of the fundamental processes in the early stages of embryonic development in...
Organism or Cell Type:
Xenopus
Citation Extract:
Vega-López GA, Bonano M, Tríbulo C, Fernández JP, Agüero TH, Aybar MJ. Functional analysis of hairy genes in Xenopus neural crest initial specification and cell migration. Dev Dyn. 2015 May 22. doi: 10.1002/dvdy.24295. [Epub ahead of print].

Proper Activity of Histone H3 Lysine 4 (H3K4) Methyltransferase Is Required for Morphogenesis during Zebrafish Cardiogenesis

Authors:
Kim JD, Kim E, Koun S, Ham HJ, Rhee M, Kim MJ, Huh TL
Citation:
Mol Cells. 2015 May 22. doi: 10.14348/molcells.2015.0053. [Epub ahead of print]
Epub:
Yes
Abstract:
While increasing evidence indicate the important function of histone methylation during development, how this process influence...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim JD, Kim E, Koun S, Ham HJ, Rhee M, Kim MJ, Huh TL. Proper Activity of Histone H3 Lysine 4 (H3K4) Methyltransferase Is Required for Morphogenesis during Zebrafish Cardiogenesis. Mol Cells. 2015 May 22. doi: 10.14348/molcells.2015.0053. [Epub ahead of print].

Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation

Authors:
Hou X, Zhang L, Han L, Ge J, Ma R, Zhang X, Moley K, Schedl T, Wang Q
Citation:
J Cell Sci. 2015;128:2319-29. doi:10.1242/​jcs.167049
Epub:
Not Epub
Abstract:
Pyruvate dehydrogenase kinases (PDKs) modulate energy homeostasis in multiple tissues/cell types, under various nutrient...
Organism or Cell Type:
mouse oocyte
Citation Extract:
Hou X, Zhang L, Han L, Ge J, Ma R, Zhang X, Moley K, Schedl T, Wang Q. Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation. J Cell Sci. 2015;128:2319-29. doi:10.1242/​jcs.167049.

Nitric Oxide Synthase Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay

Authors:
Ridnour LA, Cheng RY, Weiss JM, Soto-Pantoja DR, Basudhar D, Heinecke JL, Stewart A, DeGraff WG, Sowers A, Thetford A, Kesarwala AH, Roberts DD, Young HA, Mitchell JB, Trinchieri G, Wiltrout RH, Wink DA
Citation:
Cancer Res. 2015 Jul 15;75(14):2788-99. doi: 10.1158/0008-5472.CAN-14-3011. Epub 2015 May 19.
Epub:
Yes
Abstract:
Nitric oxide synthases (NOS) are important mediators of pro-growth signaling in tumor cells, as they regulate angiogenesis,...
Delivery Method:
injection (mice)
Organism or Cell Type:
cell culture: Raw 267.4, mouse
Citation Extract:
Ridnour LA, Cheng RY, Weiss JM, Soto-Pantoja DR, Basudhar D, Heinecke JL, Stewart A, DeGraff WG, Sowers A, Thetford A, Kesarwala AH, Roberts DD, Young HA, Mitchell JB, Trinchieri G, Wiltrout RH, Wink DA. Nitric Oxide Synthase Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay. Cancer Res. 2015 Jul 15;75(14):2788-99. doi: 10.1158/0008-5472.CAN-14-3011. Epub 2015 May 19..

Xenopus Claudin-6 is required for embryonic pronephros morphogenesis and terminal differentiation

Authors:
Sun J, Wang X, Li C, Mao B
Citation:
Biochem Biophys Res Commun. 2015 May 13. pii: S0006-291X(15)00755-X. doi: 10.1016/j.bbrc.2015.04.065. [Epub ahead of print]
Epub:
Yes
Abstract:
Claudins are tetratransmembrane tight junction proteins and play important roles in regulating paracellular permeability of...
Organism or Cell Type:
Xenopus
Citation Extract:
Sun J, Wang X, Li C, Mao B. Xenopus Claudin-6 is required for embryonic pronephros morphogenesis and terminal differentiation. Biochem Biophys Res Commun. 2015 May 13. pii: S0006-291X(15)00755-X. doi: 10.1016/j.bbrc.2015.04.065. [Epub ahead of print].

The c-Cbl Ubiquitin Ligase Regulates Nuclear β-Catenin and Angiogenesis by Its Tyrosine Phosphorylation Mediated through the Wnt Signaling Pathway

Authors:
Shivanna S, Harrold I, Shashar M, Meyer R, Kiang C, Francis J, Zhao Q, Feng H, Edelman ER, Rahimi N, Chitalia VC
Citation:
J Biol Chem. 2015;290:12537-46. doi:10.1074/jbc.M114.616623
Epub:
Not Epub
Abstract:
Wnt signaling plays important roles in both the tumor-induced angiogenesis and tumorigenesis through the transcriptionally...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shivanna S, Harrold I, Shashar M, Meyer R, Kiang C, Francis J, Zhao Q, Feng H, Edelman ER, Rahimi N, Chitalia VC. The c-Cbl Ubiquitin Ligase Regulates Nuclear β-Catenin and Angiogenesis by Its Tyrosine Phosphorylation Mediated through the Wnt Signaling Pathway. J Biol Chem. 2015;290:12537-46. doi:10.1074/jbc.M114.616623.

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