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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Combination antisense treatment for destructive exon skipping of myostatin and open reading frame rescue of dystrophin in neonatal mdx mice

Authors:
Lu-Nguyen NB, Jarmin SA, Saleh AF, Popplewell L, Gait MJ, Dickson G
Citation:
Mol Ther. 2015 May 11. doi: 10.1038/mt.2015.88. [Epub ahead of print]
Epub:
Yes
Abstract:
The fatal X-linked Duchenne muscular dystrophy (DMD), characterized by progressive muscle wasting and muscle weakness, is...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice, mdx
Citation Extract:
Lu-Nguyen NB, Jarmin SA, Saleh AF, Popplewell L, Gait MJ, Dickson G. Combination antisense treatment for destructive exon skipping of myostatin and open reading frame rescue of dystrophin in neonatal mdx mice. Mol Ther. 2015 May 11. doi: 10.1038/mt.2015.88. [Epub ahead of print].

Transfection of isolated rainbow trout, Oncorhynchus mykiss, granulosa cells through chemical transfection and electroporation at 12°C

Authors:
Marivin E, Mourot B, Loyer P, Rime H, Bobe J, Fostier A
Citation:
Gen Comp Endocrinol. 2015 May 6. pii: S0016-6480(15)00125-2. doi: 10.1016/j.ygcen.2015.03.012. [Epub ahead of print]
Epub:
Yes
Abstract:
Over-expression or inhibition of gene expression can be efficiently used to analyse the functions and/or regulation of target...
Delivery Method:
transfection & electroporation
Organism or Cell Type:
Oncorhynchus mykiss (rainbow trout)
Citation Extract:
Marivin E, Mourot B, Loyer P, Rime H, Bobe J, Fostier A. Transfection of isolated rainbow trout, Oncorhynchus mykiss, granulosa cells through chemical transfection and electroporation at 12°C. Gen Comp Endocrinol. 2015 May 6. pii: S0016-6480(15)00125-2. doi: 10.1016/j.ygcen.2015.03.012. [Epub ahead of print].

DLX4 is Associated With Orofacial Clefting and Abnormal Jaw Development

Authors:
Wu D, Mandal S, Choi A, Anderson A, Prochazkova M, Perry H, Gil-da-Silva-Lopes VL, Lao R, Wan E, Tang PL, Kwok PY, Klein O, Zhuan B, Slavotinek AM
Citation:
Hum Mol Genet. 2015 May 7. pii: ddv167. [Epub ahead of print]
Epub:
Yes
Abstract:
Cleft lip and/or palate (CL/P) are common structural birth defects in humans. We used exome sequencing to study a patient with...
Organism or Cell Type:
zebrafish
Citation Extract:
Wu D, Mandal S, Choi A, Anderson A, Prochazkova M, Perry H, Gil-da-Silva-Lopes VL, Lao R, Wan E, Tang PL, Kwok PY, Klein O, Zhuan B, Slavotinek AM. DLX4 is Associated With Orofacial Clefting and Abnormal Jaw Development. Hum Mol Genet. 2015 May 7. pii: ddv167. [Epub ahead of print].

The Inner Nuclear Membrane Protein Nemp1 Is a New Type of RanGTP-Binding Protein in Eukaryotes

Authors:
Shibano T, Mamada H, Hakuno F, Takahashi S, Taira M
Citation:
PLoS One. 2015 May 6;10(5):e0127271. doi: 10.1371/journal.pone.0127271. eCollection 2015
Epub:
Not Epub
Abstract:
The inner nuclear membrane (INM) protein Nemp1/TMEM194A has previously been suggested to be involved in eye development in...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Shibano T, Mamada H, Hakuno F, Takahashi S, Taira M. The Inner Nuclear Membrane Protein Nemp1 Is a New Type of RanGTP-Binding Protein in Eukaryotes. PLoS One. 2015 May 6;10(5):e0127271. doi: 10.1371/journal.pone.0127271. eCollection 2015.

Dynamics of the slowing segmentation clock reveal alternating two-segment periodicity

Authors:
Shih NP, François P, Delaune EA, Amacher SL
Citation:
Development. 2015;142:1785-93; doi:10.1242/dev.119057
Epub:
Not Epub
Abstract:
The formation of reiterated somites along the vertebrate body axis is controlled by the segmentation clock, a molecular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shih NP, François P, Delaune EA, Amacher SL. Dynamics of the slowing segmentation clock reveal alternating two-segment periodicity. Development. 2015;142:1785-93; doi:10.1242/dev.119057.

TGF-β Signaling Regulates the Differentiation of Motile Cilia

Authors:
Tözser J, Earwood R, Kato A, Brown J, Tanaka K, Didier R, Megraw TL, Blum M, Kato Y
Citation:
Cell Rep. 2015;[Epub ahead of print] doi:10.1016/j.celrep.2015.04.025
Epub:
Not Epub
Abstract:
The cilium is a small cellular organelle with motility- and/or sensory-related functions that plays a crucial role during...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Tözser J, Earwood R, Kato A, Brown J, Tanaka K, Didier R, Megraw TL, Blum M, Kato Y. TGF-β Signaling Regulates the Differentiation of Motile Cilia. Cell Rep. 2015;[Epub ahead of print] doi:10.1016/j.celrep.2015.04.025.

Hydrogen sulfide promotes calcium uptake in larval zebrafish

Authors:
Kwong RW, Perry SF
Citation:
Am J Physiol Cell Physiol. 2015 May 6:ajpcell.00053.2015. doi: 10.1152/ajpcell.00053.2015. [Epub ahead of print]
Epub:
Yes
Abstract:
Hydrogen sulfide (H2S) can act as a signalling molecule for various ion channels and/or transporters, however, little is known...
Organism or Cell Type:
zebrafish
Citation Extract:
Kwong RW, Perry SF. Hydrogen sulfide promotes calcium uptake in larval zebrafish. Am J Physiol Cell Physiol. 2015 May 6:ajpcell.00053.2015. doi: 10.1152/ajpcell.00053.2015. [Epub ahead of print].

The SLC7A7 Transporter Identifies Microglial Precursors prior to Entry into the Brain

Authors:
Rossi F, Casano AM, Henke K, Richter K, Peri F
Citation:
Cell Rep. 2015;[Epub ahead pf print] doi:10.1016/j.celrep.2015.04.028
Epub:
Yes
Abstract:
During development, macrophages invade organs to establish phenotypically and transcriptionally distinct tissue-resident...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rossi F, Casano AM, Henke K, Richter K, Peri F. The SLC7A7 Transporter Identifies Microglial Precursors prior to Entry into the Brain. Cell Rep. 2015;[Epub ahead pf print] doi:10.1016/j.celrep.2015.04.028.

Functions of idh1 and its mutation in the regulation of developmental hematopoiesis in zebrafish

Authors:
Shi X, He BL, Ma AC, Guo Y, Chi Y, Man CH, Zhang W, Zhang Y, Wen Z, Cheng T, Leung AY
Citation:
Blood. 2015 May 7;125(19):2974-84. doi: 10.1182/blood-2014-09-601187. Epub 2015 Mar 16
Epub:
Not Epub
Abstract:
Isocitrate dehydrogenase 1 mutation (IDH1-R132H) was recently identified in acute myeloid leukemia with normal cytogenetics....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shi X, He BL, Ma AC, Guo Y, Chi Y, Man CH, Zhang W, Zhang Y, Wen Z, Cheng T, Leung AY. Functions of idh1 and its mutation in the regulation of developmental hematopoiesis in zebrafish. Blood. 2015 May 7;125(19):2974-84. doi: 10.1182/blood-2014-09-601187. Epub 2015 Mar 16.

State-of-the-Art Workshops on Medical Countermeasures Potentially Available for Human Use Following Accidental Exposures to Ebola Virus

Authors:
Jahrling PB, Hensley LE, Barrett K, Lane HC, Davey RT
Citation:
J Infect Dis. 2015 Oct 1;212 Suppl 2(Suppl 2):S84-90. doi: 10.1093/infdis/jiv115. Epub 2015 May 9. PMID: 25957962; PMCID: PMC4564537
Epub:
Yes
Abstract:
The ongoing outbreak of Ebola in West Africa has raised a general awareness that at present there are no Ebola-specific medical...
Citation Extract:
Jahrling PB, Hensley LE, Barrett K, Lane HC, Davey RT. State-of-the-Art Workshops on Medical Countermeasures Potentially Available for Human Use Following Accidental Exposures to Ebola Virus. J Infect Dis. 2015 Oct 1;212 Suppl 2(Suppl 2):S84-90. doi: 10.1093/infdis/jiv115. Epub 2015 May 9. PMID: 25957962; PMCID: PMC4564537.

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