You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

The PBDE metabolite 6-OH-BDE 47 affects melanin pigmentation and THRβ MRNA expression in the eye of zebrafish embryos

Authors:
Dong W, Macaulay LJ, Kwok KW, Hinton DE, Ferguson PL, Stapleton HM
Citation:
Endocr Disruptors (Austin). 2014;2(1). pii: e969072
Epub:
Not Epub
Abstract:
Polybrominated diphenyl ethers and their hydroxyl-metabolites (OH-BDEs) are commonly detected contaminants in human serum in...
Link:
http://www.tandfonline.com/doi/abs/10.4161/23273739.2014.969072#.VTFUGZNtETY
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dong W, Macaulay LJ, Kwok KW, Hinton DE, Ferguson PL, Stapleton HM. The PBDE metabolite 6-OH-BDE 47 affects melanin pigmentation and THRβ MRNA expression in the eye of zebrafish embryos. Endocr Disruptors (Austin). 2014;2(1). pii: e969072.

Endothelial Cell Self-fusion during Vascular Pruning

Authors:
Lenard A, Daetwyler S, Betz C, Ellertsdottir E, Belting H-G, Huisken J, Affolter M
Citation:
PLoS Biol. 2015;13(4):e1002126. doi:10.1371/journal.pbio.1002126
Epub:
Not Epub
Abstract:
During embryonic development, vascular networks remodel to meet the increasing demand of growing tissues for oxygen and...
Link:
http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002126
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lenard A, Daetwyler S, Betz C, Ellertsdottir E, Belting H-G, Huisken J, Affolter M. Endothelial Cell Self-fusion during Vascular Pruning. PLoS Biol. 2015;13(4):e1002126. doi:10.1371/journal.pbio.1002126.

Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity

Authors:
Fukushima T, Yoshihara H, Furuta H, Kamei H, Hakuno F, Luan J, Duan C, Saeki Y, Tanaka K, Iemura S-I, Natsume T, Chida K, Nakatsu Y, Kamata H, Asano T, Takahashi S-I
Citation:
Nat Comm. 2015;6:6750. doi:10.1038/ncomms7780
Epub:
Not Epub
Abstract:
Insulin-like growth factors (IGFs) induce proliferation of various cell types and play important roles in somatic growth and...
Link:
http://www.nature.com/ncomms/2015/150416/ncomms7780/full/ncomms7780.html#abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fukushima T, Yoshihara H, Furuta H, Kamei H, Hakuno F, Luan J, Duan C, Saeki Y, Tanaka K, Iemura S-I, Natsume T, Chida K, Nakatsu Y, Kamata H, Asano T, Takahashi S-I. Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity. Nat Comm. 2015;6:6750. doi:10.1038/ncomms7780.

Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point

Authors:
Baeyens N, Nicoli S, Coon BG, Ross TD, Van den Dries K, Han J, Lauridsen HM, Mejean CO, Eichmann A, Thomas JL, Humphrey JD, Schwartz MA
Citation:
Elife. 2015 Feb 2;4. doi: 10.7554/eLife.04645
Epub:
Not Epub
Abstract:
Vascular remodeling under conditions of growth or exercise, or during recovery from arterial restriction or blockage is...
Link:
http://elifesciences.org/content/4/e04645
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Baeyens N, Nicoli S, Coon BG, Ross TD, Van den Dries K, Han J, Lauridsen HM, Mejean CO, Eichmann A, Thomas JL, Humphrey JD, Schwartz MA. Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point. Elife. 2015 Feb 2;4. doi: 10.7554/eLife.04645.

Defective apical extrusion signaling contributes to aggressive tumor hallmarks

Authors:
Gu Y, Shea J, Slattum G, Firpo MA, Alexander M, Mulvihill SJ, Golubovskaya VM, Rosenblatt J
Citation:
Elife. 2015 Jan 26;4:e04069. doi: 10.7554/eLife.04069
Epub:
Not Epub
Abstract:
When epithelia become too crowded, some cells are extruded that later die. To extrude, a cell produces the lipid, Sphingosine 1...
Link:
http://elifesciences.org/content/4/e04069
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gu Y, Shea J, Slattum G, Firpo MA, Alexander M, Mulvihill SJ, Golubovskaya VM, Rosenblatt J. Defective apical extrusion signaling contributes to aggressive tumor hallmarks. Elife. 2015 Jan 26;4:e04069. doi: 10.7554/eLife.04069.

Neural crest specification and migration independently require NSD3-related lysine methyltransferase activity

Authors:
Jacques-Fricke BT, Gammill LS
Citation:
Mol Biol Cell. 2014 Dec 15;25(25):4174-86. doi: 10.1091/mbc.E13-12-0744. Epub 2014 Oct 15
Epub:
Not Epub
Abstract:
Neural crest precursors express genes that cause them to become migratory, multipotent cells, distinguishing them from adjacent...
Link:
http://www.molbiolcell.org/content/25/25/4174.abstract
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Jacques-Fricke BT, Gammill LS. Neural crest specification and migration independently require NSD3-related lysine methyltransferase activity. Mol Biol Cell. 2014 Dec 15;25(25):4174-86. doi: 10.1091/mbc.E13-12-0744. Epub 2014 Oct 15.

GSK3 and Polo-like kinase regulate ADAM13 function during cranial neural crest cell migration

Authors:
Abbruzzese G, Cousin H, Salicioni AM, Alfandari D
Citation:
Mol Biol Cell. 2014 Dec 15;25(25):4072-82. doi: 10.1091/mbc.E14-05-0970. Epub 2014 Oct 8
Epub:
Not Epub
Abstract:
ADAMs are cell surface metalloproteases that control multiple biological processes by cleaving signaling and adhesion molecules...
Link:
http://www.molbiolcell.org/content/25/25/4072.long
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Abbruzzese G, Cousin H, Salicioni AM, Alfandari D. GSK3 and Polo-like kinase regulate ADAM13 function during cranial neural crest cell migration. Mol Biol Cell. 2014 Dec 15;25(25):4072-82. doi: 10.1091/mbc.E14-05-0970. Epub 2014 Oct 8.

PICALM modulates autophagy activity and tau accumulation

Authors:
Moreau K, Fleming A, Imarisio S, Lopez Ramirez A, Mercer JL, Jimenez-Sanchez M, Bento CF, Puri C, Zavodszky E, Siddiqi F, Lavau CP, Betton M, O'Kane CJ, Wechsler DS, Rubinsztein DC
Citation:
Nat Commun. 2014 Sep 22;5:4998. doi: 10.1038/ncomms5998
Epub:
Not Epub
Abstract:
Genome-wide association studies have identified several loci associated with Alzheimer’s disease (AD), including proteins...
Link:
http://www.nature.com/ncomms/2014/140922/ncomms5998/full/ncomms5998.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Moreau K, Fleming A, Imarisio S, Lopez Ramirez A, Mercer JL, Jimenez-Sanchez M, Bento CF, Puri C, Zavodszky E, Siddiqi F, Lavau CP, Betton M, O'Kane CJ, Wechsler DS, Rubinsztein DC. PICALM modulates autophagy activity and tau accumulation. Nat Commun. 2014 Sep 22;5:4998. doi: 10.1038/ncomms5998.

Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development

Authors:
Holtzhausen A, Golzio C, How T, Lee YH, Schiemann WP, Katsanis N, Blobe GC
Citation:
FASEB J. 2014 Mar;28(3):1248-67. doi: 10.1096/fj.13-239178. Epub 2013 Dec 5
Epub:
Not Epub
Abstract:
The bone morphogenetic protein (BMP) signaling pathways have important roles in embryonic development and cellular homeostasis...
Link:
http://www.fasebj.org/content/28/3/1248.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Holtzhausen A, Golzio C, How T, Lee YH, Schiemann WP, Katsanis N, Blobe GC. Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development. FASEB J. 2014 Mar;28(3):1248-67. doi: 10.1096/fj.13-239178. Epub 2013 Dec 5.

Loss of dihydrolipoyl succinyltransferase (DLST) leads to reduced resting heart rate in the zebrafish

Authors:
Keßler M, Berger IM, Just S, Rottbauer W
Citation:
Basic Res Cardiol. 2015 Mar;110(2):14. doi: 10.1007/s00395-015-0468-7. Epub 2015 Feb 20
Epub:
Not Epub
Abstract:
The genetic underpinnings of heart rate regulation are only poorly understood. In search for genetic regulators of cardiac...
Link:
http://link.springer.com/article/10.1007%2Fs00395-015-0468-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Keßler M, Berger IM, Just S, Rottbauer W. Loss of dihydrolipoyl succinyltransferase (DLST) leads to reduced resting heart rate in the zebrafish. Basic Res Cardiol. 2015 Mar;110(2):14. doi: 10.1007/s00395-015-0468-7. Epub 2015 Feb 20.

Pages