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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

The Proprotein Convertase Subtilisin/Kexin FurinA Regulates Zebrafish Host Response against Mycobacterium marinum

Authors:
Ojanen MJ, Turpeinen H, Cordova ZM, Hammarén MM, Harjula SK, Parikka M, Rämet M, Pesu M
Citation:
Infect Immun. April 2015 83:4 1431-1442; Accepted manuscript posted online 26 January 2015, doi: 10.1128/IAI.03135-14
Epub:
Not Epub
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ojanen MJ, Turpeinen H, Cordova ZM, Hammarén MM, Harjula SK, Parikka M, Rämet M, Pesu M. The Proprotein Convertase Subtilisin/Kexin FurinA Regulates Zebrafish Host Response against Mycobacterium marinum. Infect Immun. April 2015 83:4 1431-1442; Accepted manuscript posted online 26 January 2015, doi: 10.1128/IAI.03135-14.

Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts

Authors:
Chu B-B, Liao Y-C, Qi W, Xie C, Du X, Wang J, Yang H, Miao H-H, Li B-L, Song B-L
Citation:
Cell. 2015;291-306. doi:10.1016/j.cell.2015.02.019
Epub:
Not Epub
Abstract:
Cholesterol is dynamically transported among organelles, which is essential for multiple cellular functions. However, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chu B-B, Liao Y-C, Qi W, Xie C, Du X, Wang J, Yang H, Miao H-H, Li B-L, Song B-L. Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts. Cell. 2015;291-306. doi:10.1016/j.cell.2015.02.019.

Fascin1-dependent Filopodia are required for directional migration of a subset of neural crest cells

Authors:
Boer EF, Howell ED, Schilling TF, Jette CA, Stewart RA
Citation:
PLoS Genet. 2015 Jan 21;11(1):e1004946. doi: 10.1371/journal.pgen.1004946. eCollection 2015 Jan
Epub:
Not Epub
Abstract:
Directional migration of neural crest (NC) cells is essential for patterning the vertebrate embryo, including the craniofacial...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boer EF, Howell ED, Schilling TF, Jette CA, Stewart RA. Fascin1-dependent Filopodia are required for directional migration of a subset of neural crest cells. PLoS Genet. 2015 Jan 21;11(1):e1004946. doi: 10.1371/journal.pgen.1004946. eCollection 2015 Jan.

HOMER2, a Stereociliary Scaffolding Protein, Is Essential for Normal Hearing in Humans and Mice

Authors:
Azaiez H, Decker AR, Booth KT, Simpson AC, Shearer AE, Huygen PL, Bu F, Hildebrand MS, Ranum PT, Shibata SB, Turner A, Zhang Y, Kimberling WJ, Cornell RA, Smith RJ
Citation:
PLoS Genet. 2015 Mar 27;11(3):e1005137. doi: 10.1371/journal.pgen.1005137. eCollection 2015 Feb
Epub:
Not Epub
Abstract:
Hereditary hearing loss is a clinically and genetically heterogeneous disorder. More than 80 genes have been implicated to date...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Azaiez H, Decker AR, Booth KT, Simpson AC, Shearer AE, Huygen PL, Bu F, Hildebrand MS, Ranum PT, Shibata SB, Turner A, Zhang Y, Kimberling WJ, Cornell RA, Smith RJ. HOMER2, a Stereociliary Scaffolding Protein, Is Essential for Normal Hearing in Humans and Mice. PLoS Genet. 2015 Mar 27;11(3):e1005137. doi: 10.1371/journal.pgen.1005137. eCollection 2015 Feb.

The Lowe Syndrome Protein OCRL1 Is Required for Endocytosis in the Zebrafish Pronephric Tubule

Authors:
Oltrabella F, Pietka G, Ramirez IB-R, Mironov A, Starborg T, Drummond IA, Hinchliffe KA, Lowe M
Citation:
PLoS Genet. 2015;11(4):e1005058. doi:10.1371/journal.pgen.1005058
Epub:
Not Epub
Abstract:
Lowe syndrome and Dent-2 disease are caused by mutation of the inositol 5-phosphatase OCRL1. Despite our increased...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Oltrabella F, Pietka G, Ramirez IB-R, Mironov A, Starborg T, Drummond IA, Hinchliffe KA, Lowe M. The Lowe Syndrome Protein OCRL1 Is Required for Endocytosis in the Zebrafish Pronephric Tubule. PLoS Genet. 2015;11(4):e1005058. doi:10.1371/journal.pgen.1005058.

Functional Characterization of the spf/ash Splicing Variation in OTC Deficiency of Mice and Man

Authors:
Rivera-Barahona A, Sánchez-Alcudia R, Viecelli HM, Rüfenacht V, Pérez B, Ugarte M, Häberle J, Thöny B, Desviat LR
Citation:
PLoS ONE. 2015;10(4):e0122966. doi:10.1371/journal.pone.0122966
Epub:
Not Epub
Abstract:
The spf/ash mouse model of ornithine transcarbamylase (OTC) deficiency, a severe urea cycle disorder, is caused by a mutation (...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: Hep3B cells
Citation Extract:
Rivera-Barahona A, Sánchez-Alcudia R, Viecelli HM, Rüfenacht V, Pérez B, Ugarte M, Häberle J, Thöny B, Desviat LR. Functional Characterization of the spf/ash Splicing Variation in OTC Deficiency of Mice and Man. PLoS ONE. 2015;10(4):e0122966. doi:10.1371/journal.pone.0122966.

Dendrimer Conjugates for Light-activated Delivery of Antisense Oligonucleotides

Authors:
Yuan A, Hu Y, Ming X
Citation:
RSC Adv. 2015;{Epub ahead of print] doi:10.1039/C5RA04091D
Epub:
Yes
Abstract:
Therapeutic oligonucleotides, such as splice switching ONs (SSOs), provide opportunity for treating serious, life-threatening...
Delivery Method:
nanoparticle with photointernalization
Organism or Cell Type:
cell culture: A375 melanoma cells
Citation Extract:
Yuan A, Hu Y, Ming X. Dendrimer Conjugates for Light-activated Delivery of Antisense Oligonucleotides. RSC Adv. 2015;{Epub ahead of print] doi:10.1039/C5RA04091D.

Incomplete splicing of neutrophil-specific genes affects neutrophil development in a zebrafish model of poikiloderma with neutropenia

Authors:
Patil P, Uechi T, Kenmochi N
Citation:
RNA Biol. 2015 Apr 3;12(4):426-434
Epub:
Not Epub
Abstract:
Poikiloderma with neutropenia (PN) is a rare inherited disorder characterized by poikiloderma, facial dysmorphism, pachyonychia...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Patil P, Uechi T, Kenmochi N. Incomplete splicing of neutrophil-specific genes affects neutrophil development in a zebrafish model of poikiloderma with neutropenia. RNA Biol. 2015 Apr 3;12(4):426-434.

Notum Is Required for Neural and Head Induction via Wnt Deacylation, Oxidation, and Inactivation

Authors:
Zhang X, Cheong S-M, Amado NG, Reis AH, MacDonald BT, Zebisch M, Jones EY, Abreu JG, He X
Citation:
Dev Cell. 2015;32(6):719-30. doi:10.1016/j.devcel.2015.02.014
Epub:
Not Epub
Abstract:
Secreted Wnt morphogens are essential for embryogenesis and homeostasis and require a lipid/palmitoleoylate modification for...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Zhang X, Cheong S-M, Amado NG, Reis AH, MacDonald BT, Zebisch M, Jones EY, Abreu JG, He X. Notum Is Required for Neural and Head Induction via Wnt Deacylation, Oxidation, and Inactivation. Dev Cell. 2015;32(6):719-30. doi:10.1016/j.devcel.2015.02.014.

Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction

Authors:
Akizu N, Cantagrel V, Zaki MS, Al-Gazali L, Wang X, Rosti RO, Dikoglu E, Gelot AB, Rosti B, Vaux KK, Scott EM, Silhavy JL, Schroth J, Copeland B, Schaffer AE, Gordts PLSM, Esko JD, Buschman MD, Field SJ, Napolitano G, Abdel-Salam GM, Ozgul RK, Sagıroglu MS, Azam M, Ismail S, Aglan M, Selim L, Mahmoud IG, Abdel-Hadi S, Badawy AE, Sadek AA, Mojahedi F, Kayserili H, Masri A, Bastaki L, Temtamy S, Müller U, Desguerre I, Casanova J-L, Dursun A, Gunel M, Gabriel SB, de Lonlay P, Gleeson JG
Citation:
Nat Genet. 2015;[Epub ahead of print] doi:10.1038/ng.3256
Epub:
Yes
Abstract:
Pediatric-onset ataxias often present clinically as developmental delay and intellectual disability, with prominent cerebellar...
Organism or Cell Type:
zebrafish
Citation Extract:
Akizu N, Cantagrel V, Zaki MS, Al-Gazali L, Wang X, Rosti RO, Dikoglu E, Gelot AB, Rosti B, Vaux KK, Scott EM, Silhavy JL, Schroth J, Copeland B, Schaffer AE, Gordts PLSM, Esko JD, Buschman MD, Field SJ, Napolitano G, Abdel-Salam GM, Ozgul RK, Sagıroglu MS, Azam M, Ismail S, Aglan M, Selim L, Mahmoud IG, Abdel-Hadi S, Badawy AE, Sadek AA, Mojahedi F, Kayserili H, Masri A, Bastaki L, Temtamy S, Müller U, Desguerre I, Casanova J-L, Dursun A, Gunel M, Gabriel SB, de Lonlay P, Gleeson JG. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction. Nat Genet. 2015;[Epub ahead of print] doi:10.1038/ng.3256.

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