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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12355 scientific papers returned from the database with the search filters currently being used below.

DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish

Authors:
Liu X, Jia X, Yuan H, Ma K, Chen Y, Jin Y, Deng M, Pan W, Chen S, Chen Z, de The H, Zon LI, Zhou Y, Jun Zhou, Jun Zhu J
Citation:
J Hematol Oncol. 2015;8:15. doi:10.1186/s13045-015-0115-7
Epub:
Not Epub
Abstract:
Background DNA methyltransferase 1 (Dnmt1) regulates expression of many critical genes through maintaining parental DNA...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu X, Jia X, Yuan H, Ma K, Chen Y, Jin Y, Deng M, Pan W, Chen S, Chen Z, de The H, Zon LI, Zhou Y, Jun Zhou, Jun Zhu J. DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish. J Hematol Oncol. 2015;8:15. doi:10.1186/s13045-015-0115-7.

Evaluation of Zebrafish Kidney Function Using a Fluorescent Clearance Assay

Authors:
Christou-Savina S, Beales PL, Osborn DPS
Citation:
J Vis Exp. 2015;96:e52540. doi:10.3791/52540
Epub:
Not Epub
Abstract:
The zebrafish embryo offers a tractable model to study organogenesis and model human genetic disease. Despite its relative...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Christou-Savina S, Beales PL, Osborn DPS. Evaluation of Zebrafish Kidney Function Using a Fluorescent Clearance Assay. J Vis Exp. 2015;96:e52540. doi:10.3791/52540.

The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211

Authors:
Petersen SC, Luo R, Liebscher I, Giera S, Jeong S-J, Mogha A, Ghidinelli M, Feltri ML, Schöneberg T, Piao X, Monk KR
Citation:
Neuron. 2015;85(4):755-69. doi:10.1016/j.neuron.2014.12.057
Epub:
Not Epub
Abstract:
Myelin ensheathes axons to allow rapid propagation of action potentials and proper nervous system function. In the peripheral...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Petersen SC, Luo R, Liebscher I, Giera S, Jeong S-J, Mogha A, Ghidinelli M, Feltri ML, Schöneberg T, Piao X, Monk KR. The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211. Neuron. 2015;85(4):755-69. doi:10.1016/j.neuron.2014.12.057.

A cnidarian homologue of an insect gustatory receptor functions in developmental body patterning

Authors:
Saina M, Busengdal H, Sinigaglia C, Petrone L, Oliveri P, Rentzsch F, Benton R
Citation:
Nat Commun. 2015 Feb 18;6:6243. doi: 10.1038/ncomms7243
Epub:
Not Epub
Abstract:
Insect gustatory and odorant receptors (GRs and ORs) form a superfamily of novel transmembrane proteins, which are expressed in...
Organism or Cell Type:
Nematostella vectensis (cnidarian)
Citation Extract:
Saina M, Busengdal H, Sinigaglia C, Petrone L, Oliveri P, Rentzsch F, Benton R. A cnidarian homologue of an insect gustatory receptor functions in developmental body patterning. Nat Commun. 2015 Feb 18;6:6243. doi: 10.1038/ncomms7243.

Chronic administration of the methylxanthine propentofylline impairs reinstatement to cocaine by a GLT-1-dependent mechanism

Authors:
Reissner KJ, Brown RM, Spencer S, Tran PK, Thomas CA, Kalivas PW
Citation:
Neuropsychopharmacology. 2014 Jan;39(2):499-506. doi: 10.1038/npp.2013.223. Epub 2013 Aug 29
Epub:
Not Epub
Abstract:
In recent years, interactions between neurons and glia have been evaluated as mediators of neuropsychiatric diseases, including...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
rat
Citation Extract:
Reissner KJ, Brown RM, Spencer S, Tran PK, Thomas CA, Kalivas PW. Chronic administration of the methylxanthine propentofylline impairs reinstatement to cocaine by a GLT-1-dependent mechanism. Neuropsychopharmacology. 2014 Jan;39(2):499-506. doi: 10.1038/npp.2013.223. Epub 2013 Aug 29.

Comparison between two labeled agents in mice using a coinjection-ratio approach in contrast to a conventional group approach

Authors:
Dou S, Wang Y, Barton B, Chen L, Rusckowski M, Shultz LD, Greiner DL, Liu G
Citation:
Nucl Med Biol. 2014 Jan;41(1):127-31. doi: 10.1016/j.nucmedbio.2013.10.001. Epub 2013 Oct 9
Epub:
Not Epub
Abstract:
INTRODUCTION: The differences between two agents often need to be accurately defined in vivo. Usually they are injected...
Organism or Cell Type:
mice
Citation Extract:
Dou S, Wang Y, Barton B, Chen L, Rusckowski M, Shultz LD, Greiner DL, Liu G. Comparison between two labeled agents in mice using a coinjection-ratio approach in contrast to a conventional group approach. Nucl Med Biol. 2014 Jan;41(1):127-31. doi: 10.1016/j.nucmedbio.2013.10.001. Epub 2013 Oct 9.

In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation

Authors:
Hegde V, Hickerson RP, Nainamalai S, Campbell PA, Smith FJ, McLean WH, Pedrioli DM
Citation:
J Control Release. 2014 Dec 28;196:355-62. doi: 10.1016/j.jconrel.2014.10.022. Epub 2014 Oct 30
Epub:
Not Epub
Abstract:
Therapeutics based on short interfering RNAs (siRNAs), which act by inhibiting the expression of target transcripts, represent...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Hegde V, Hickerson RP, Nainamalai S, Campbell PA, Smith FJ, McLean WH, Pedrioli DM. In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation. J Control Release. 2014 Dec 28;196:355-62. doi: 10.1016/j.jconrel.2014.10.022. Epub 2014 Oct 30.

Long-chain Acyl-CoA synthetase 4A regulates Smad activity and dorsoventral patterning in the zebrafish embryo

Authors:
Miyares RL, Stein C, Renisch B, Anderson JL, Hammerschmidt M, Farber SA
Citation:
Dev Cell. 2013 Dec 23;27(6):635-47. doi: 10.1016/j.devcel.2013.11.011. Epub 2013 Dec 12
Epub:
Not Epub
Abstract:
Long-chain polyunsaturated fatty acids (LC-PUFA) and their metabolites are critical players in cell biology and embryonic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miyares RL, Stein C, Renisch B, Anderson JL, Hammerschmidt M, Farber SA. Long-chain Acyl-CoA synthetase 4A regulates Smad activity and dorsoventral patterning in the zebrafish embryo. Dev Cell. 2013 Dec 23;27(6):635-47. doi: 10.1016/j.devcel.2013.11.011. Epub 2013 Dec 12.

Several cis-regulatory elements control mRNA stability, translation efficiency, and expression pattern of Prrxl1 (paired related homeobox protein-like 1)

Authors:
Regadas I, Matos MR, Monteiro FA, Gómez-Skarmeta JL, Lima D, Bessa J, Casares F, Reguenga C
Citation:
J Biol Chem. 2013 Dec 20;288(51):36285-301. doi: 10.1074/jbc.M113.491993. Epub 2013 Nov 8
Epub:
Not Epub
Abstract:
The homeodomain transcription factor Prrxl1/DRG11 has emerged as a crucial molecule in the establishment of the pain circuitry...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Regadas I, Matos MR, Monteiro FA, Gómez-Skarmeta JL, Lima D, Bessa J, Casares F, Reguenga C. Several cis-regulatory elements control mRNA stability, translation efficiency, and expression pattern of Prrxl1 (paired related homeobox protein-like 1). J Biol Chem. 2013 Dec 20;288(51):36285-301. doi: 10.1074/jbc.M113.491993. Epub 2013 Nov 8.

IQGAP1 protein regulates nuclear localization of β-catenin via importin-β5 protein in Wnt signaling

Authors:
Goto T, Sato A, Adachi S, Iemura S, Natsume T, Shibuya H
Citation:
J Biol Chem. 2013 Dec 20;288(51):36351-60. doi: 10.1074/jbc.M113.520528. Epub 2013 Nov 6
Epub:
Not Epub
Abstract:
In the canonical Wnt signaling pathway, the translocation of β-catenin is important for the activation of target genes in the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Goto T, Sato A, Adachi S, Iemura S, Natsume T, Shibuya H. IQGAP1 protein regulates nuclear localization of β-catenin via importin-β5 protein in Wnt signaling. J Biol Chem. 2013 Dec 20;288(51):36351-60. doi: 10.1074/jbc.M113.520528. Epub 2013 Nov 6.

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