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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12356 scientific papers returned from the database with the search filters currently being used below.

Snail2/Slug cooperates with Polycomb repressive complex 2 (PRC2) to regulate neural crest development

Authors:
Tien CL, Jones A, Wang H, Gerigk M, Nozell S, Chang C
Citation:
Development. 2015 Jan 23. pii: dev.111997. [Epub ahead of print]
Epub:
Yes
Abstract:
Neural crest cells arise from the border of the neural plate and epidermal ectoderm, migrate extensively and differentiate into...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Tien CL, Jones A, Wang H, Gerigk M, Nozell S, Chang C. Snail2/Slug cooperates with Polycomb repressive complex 2 (PRC2) to regulate neural crest development. Development. 2015 Jan 23. pii: dev.111997. [Epub ahead of print].

LOXL3, encoding lysyl oxidase-like 3, is mutated in a family with autosomal recessive Stickler syndrome

Authors:
Alzahrani F, Al Hazzaa SA, Tayeb H, Alkuraya FS
Citation:
Hum Genet. 2015 Feb 7. [Epub ahead of print]
Epub:
Yes
Abstract:
Stickler syndrome (SS) is a collagenopathy characterized by arthropathy and vitreoretinopathy with high myopia and cleft palate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Alzahrani F, Al Hazzaa SA, Tayeb H, Alkuraya FS. LOXL3, encoding lysyl oxidase-like 3, is mutated in a family with autosomal recessive Stickler syndrome. Hum Genet. 2015 Feb 7. [Epub ahead of print].

Cep55 regulates embryonic growth and development by promoting Akt stability in zebrafish

Authors:
Jeffery J, Neyt C, Moore W, Paterson S, Bower NI, Chenevix-Trench G, Verkade H, Hogan BM, Khanna KK
Citation:
FASEB J. 2015 Feb 9. pii: fj.14-265090. [Epub ahead of print]
Epub:
Yes
Abstract:
CEP55 was initially described as a centrosome- and midbody-associated protein and a key mediator of cytokinesis. More recently...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jeffery J, Neyt C, Moore W, Paterson S, Bower NI, Chenevix-Trench G, Verkade H, Hogan BM, Khanna KK. Cep55 regulates embryonic growth and development by promoting Akt stability in zebrafish. FASEB J. 2015 Feb 9. pii: fj.14-265090. [Epub ahead of print].

Quantitative study of proteomic alterations in a Zebrafish (danio rerio) cell line infected with the Singapore Grouper Iridovirus (SGIV)

Authors:
Wang F, Zhu Y, Hew CL
Citation:
Virus Res. 2015 Mar 2;199:62-7. doi: 10.1016/j.virusres.2015.01.025. Epub 2015 Feb 4. PMID: 25662022
Epub:
Yes
Abstract:
We demonstrate, for the first time, that Singapore Grouper Iridovirus (SGIV) can successfully infect a Zebrafish cell line....
Organism or Cell Type:
cell culture: Singapore Grouper Iridovirus (SGIV) infected zebrafish cell line
Citation Extract:
Wang F, Zhu Y, Hew CL. Quantitative study of proteomic alterations in a Zebrafish (danio rerio) cell line infected with the Singapore Grouper Iridovirus (SGIV). Virus Res. 2015 Mar 2;199:62-7. doi: 10.1016/j.virusres.2015.01.025. Epub 2015 Feb 4. PMID: 25662022.

UXT potentiates angiogenesis by attenuating Notch signaling

Authors:
Zhou Y, Ge R, Wang R, Liu F, Huang Y, Liu H, Hao Y, Zhou Q, Wang C
Citation:
Development. 2015;142:774-86. [Epub ahead of print] doi:10.1242/dev.112532
Epub:
Not Epub
Abstract:
. . Angiogenesis is spatially and temporally orchestrated by a myriad of signaling pathways, including the Notch signaling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou Y, Ge R, Wang R, Liu F, Huang Y, Liu H, Hao Y, Zhou Q, Wang C. UXT potentiates angiogenesis by attenuating Notch signaling. Development. 2015;142:774-86. [Epub ahead of print] doi:10.1242/dev.112532.

Structural and functional properties of ryanodine receptor type 3 in zebrafish tail muscle

Authors:
Perni S, Marsden KC, Escobar M, Hollingworth S, Baylor SM, Franzini-Armstrong C
Citation:
J Gen Physiol. 2015;[Epub ahead of print], doi:10.1085/jgp.201411303
Epub:
Yes
Abstract:
The ryanodine receptor (RyR)1 isoform of the sarcoplasmic reticulum (SR) Ca2+ release channel is an essential component of all...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Perni S, Marsden KC, Escobar M, Hollingworth S, Baylor SM, Franzini-Armstrong C. Structural and functional properties of ryanodine receptor type 3 in zebrafish tail muscle. J Gen Physiol. 2015;[Epub ahead of print], doi:10.1085/jgp.201411303 .

A single phosphorodiamidate morpholino oligomer targeting VP24 protects rhesus monkeys against lethal Ebola virus infection

Authors:
Warren TK, Whitehouse CA, Wells J, Welch L, Heald AE, Charleston JS, Sazani P, Reid SP, Iversen PL, Bavari S
Citation:
mBio. 2015;6(1):e02344-14. doi:10.1128/mBio.02344-14
Epub:
Not Epub
Abstract:
Ebola viruses (EBOV) cause severe disease in humans and nonhuman primates with high mortality rates and continue to emerge in...
Delivery Method:
intravenous
Organism or Cell Type:
Macaca mulatta (Rhesus monkey)
Citation Extract:
Warren TK, Whitehouse CA, Wells J, Welch L, Heald AE, Charleston JS, Sazani P, Reid SP, Iversen PL, Bavari S. A single phosphorodiamidate morpholino oligomer targeting VP24 protects rhesus monkeys against lethal Ebola virus infection. mBio. 2015;6(1):e02344-14. doi:10.1128/mBio.02344-14.

Mediator Med23 deficiency enhances neural differentiation of murine embryonic stem cells through modulating BMP signaling

Authors:
Zhu W, Yao X, Liang Y, Liang D, Song L, Jing N, Li J, Wang G
Citation:
Development. 2015 Feb 1;142(3):465-76. doi: 10.1242/dev.112946. Epub 2015 Jan 6
Epub:
Not Epub
Abstract:
Unraveling the mechanisms underlying early neural differentiation of embryonic stem cells (ESCs) is crucial to developing cell-...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhu W, Yao X, Liang Y, Liang D, Song L, Jing N, Li J, Wang G. Mediator Med23 deficiency enhances neural differentiation of murine embryonic stem cells through modulating BMP signaling. Development. 2015 Feb 1;142(3):465-76. doi: 10.1242/dev.112946. Epub 2015 Jan 6.

Glucocerebrosidase deficiency in zebrafish affects primary bone ossification through increased oxidative stress and reduced Wnt/β-catenin signaling

Authors:
Zancan I, Bellesso S, Costa R, Salvalaio M, Stroppiano M, Hammond C, Argenton F, Filocamo M, Moro E
Citation:
Hum Mol Genet. 2014 Oct 17. pii: ddu538. [Epub ahead of print]
Epub:
Yes
Abstract:
Loss of lysosomal glucocerebrosidase (GBA1) function is responsible for several organ defects, including skeletal abnormalities...
Organism or Cell Type:
zebrafish
Citation Extract:
Zancan I, Bellesso S, Costa R, Salvalaio M, Stroppiano M, Hammond C, Argenton F, Filocamo M, Moro E. Glucocerebrosidase deficiency in zebrafish affects primary bone ossification through increased oxidative stress and reduced Wnt/β-catenin signaling. Hum Mol Genet. 2014 Oct 17. pii: ddu538. [Epub ahead of print].

A Novel TGFβ Modulator that Uncouples R-Smad/I-Smad-Mediated Negative Feedback from R-Smad/Ligand-Driven Positive Feedback

Authors:
Gu W, Monteiro R, Zuo J, Simões FC, Martella A, Andrieu-Soler C, Grosveld F, Sauka-Spengler T, Patient R
Citation:
PLoS Biol. 2015;13(2):e1002051. doi:10.1371/journal.pbio.1002051
Epub:
Not Epub
Abstract:
As some of the most widely utilised intercellular signalling molecules, transforming growth factor β (TGFβ) superfamily members...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gu W, Monteiro R, Zuo J, Simões FC, Martella A, Andrieu-Soler C, Grosveld F, Sauka-Spengler T, Patient R. A Novel TGFβ Modulator that Uncouples R-Smad/I-Smad-Mediated Negative Feedback from R-Smad/Ligand-Driven Positive Feedback. PLoS Biol. 2015;13(2):e1002051. doi:10.1371/journal.pbio.1002051.

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