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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12359 scientific papers returned from the database with the search filters currently being used below.

The Cerebral Cavernous Malformation Pathway Controls Cardiac Development via Regulation of Endocardial MEKK3 Signaling and KLF Expression

Authors:
Zhou Z, Rawnsley DR, Goddard LM, Pan W, Cao XJ, Jakus Z, Zheng H, Yang J, Arthur JS, Whitehead KJ, Li D, Zhou B, Garcia BA, Zheng X, Kahn ML
Citation:
Dev Cell. 2015 Jan 26;32(2):168-80. doi: 10.1016/j.devcel.2014.12.009
Epub:
Not Epub
Abstract:
The cerebral cavernous malformation (CCM) pathway is required in endothelial cells for normal cardiovascular development and to...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou Z, Rawnsley DR, Goddard LM, Pan W, Cao XJ, Jakus Z, Zheng H, Yang J, Arthur JS, Whitehead KJ, Li D, Zhou B, Garcia BA, Zheng X, Kahn ML. The Cerebral Cavernous Malformation Pathway Controls Cardiac Development via Regulation of Endocardial MEKK3 Signaling and KLF Expression. Dev Cell. 2015 Jan 26;32(2):168-80. doi: 10.1016/j.devcel.2014.12.009.

Detection of sequence-specific DNA with morpholino-functionalized silicon chip

Authors:
Hu W, Hu Q, Li L, Kong J, Zhang X
Citation:
Anal Methods. 2015;[Epub ahead of print] doi:10.1039/C4AY02780A
Epub:
Yes
Abstract:
In this work, an efficient method for the sequence-specific detection of DNA based on a morpholino-functionalized silicon chip...
Citation Extract:
Hu W, Hu Q, Li L, Kong J, Zhang X. Detection of sequence-specific DNA with morpholino-functionalized silicon chip. Anal Methods. 2015;[Epub ahead of print] doi:10.1039/C4AY02780A.

Hoxa2 Selectively Enhances Meis Binding to Change a Branchial Arch Ground State

Authors:
Amin S, Donaldson IJ, Zannino DA, Hensman J, Rattray M, Losa M, Spitz F, Ladam F, Sagerström C, Bobola N
Citation:
Dev Cell. 2015;[Epub ahead of print] doi:10.1016/j.devcel.2014.12.024
Epub:
Yes
Abstract:
Hox transcription factors (TFs) are essential for vertebrate development, but how these evolutionary conserved proteins...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Amin S, Donaldson IJ, Zannino DA, Hensman J, Rattray M, Losa M, Spitz F, Ladam F, Sagerström C, Bobola N. Hoxa2 Selectively Enhances Meis Binding to Change a Branchial Arch Ground State. Dev Cell. 2015;[Epub ahead of print] doi:10.1016/j.devcel.2014.12.024.

PICALM modulates autophagy activity and tau accumulation

Authors:
Moreau K, Fleming A, Imarisio S, Lopez Ramirez A, Mercer JL, Jimenez-Sanchez M, Bento CF, Puri C, Zavodszky E, Siddiqi F, Lavau CP, Betton M, O'Kane CJ, Wechsler DS, Rubinsztein DC
Citation:
Nat Commun. 2014 Sep 22;5:4998. doi: 10.1038/ncomms5998
Epub:
Not Epub
Abstract:
Genome-wide association studies have identified several loci associated with Alzheimer's disease (AD), including proteins...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Moreau K, Fleming A, Imarisio S, Lopez Ramirez A, Mercer JL, Jimenez-Sanchez M, Bento CF, Puri C, Zavodszky E, Siddiqi F, Lavau CP, Betton M, O'Kane CJ, Wechsler DS, Rubinsztein DC. PICALM modulates autophagy activity and tau accumulation. Nat Commun. 2014 Sep 22;5:4998. doi: 10.1038/ncomms5998.

Ruthenium-Caged Antisense Morpholinos for Regulating Gene Expression in Zebrafish Embryos

Authors:
Griepenburg JC, Rapp TL, Carroll P, Dmochowski I, Eberwine J
Citation:
Chem Sci. 2015;[Epub ahead of print] doi: 10.1039/C4SC03990D
Epub:
Yes
Abstract:
Photochemical approaches afford high spatiotemporal control over molecular structure and function, for broad applications in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Griepenburg JC, Rapp TL, Carroll P, Dmochowski I, Eberwine J. Ruthenium-Caged Antisense Morpholinos for Regulating Gene Expression in Zebrafish Embryos. Chem Sci. 2015;[Epub ahead of print] doi: 10.1039/C4SC03990D .

The Alternative Splicing Regulator Tra2b Is Required for Somitogenesis and Regulates Splicing of an Inhibitory Wnt11b Isoform

Authors:
Dichmann DS, Walentek P, Harland RM
Citation:
Cell Rep. 2015 Jan 21. pii: S2211-1247(14)01099-7. doi: 10.1016/j.celrep.2014.12.046. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Alternative splicing is pervasive in vertebrates, yet little is known about most isoforms or their regulation. transformer-2b (...
Organism or Cell Type:
Xenopus
Citation Extract:
Dichmann DS, Walentek P, Harland RM. The Alternative Splicing Regulator Tra2b Is Required for Somitogenesis and Regulates Splicing of an Inhibitory Wnt11b Isoform. Cell Rep. 2015 Jan 21. pii: S2211-1247(14)01099-7. doi: 10.1016/j.celrep.2014.12.046. [Epub ahead of print].

The secreted factor Ag1 missing in higher vertebrates regulates fins regeneration in Danio rerio

Authors:
Ivanova AS, Shandarin IN, Ermakova GV, Minin AA, Tereshina MB, Zaraisky AG
Citation:
Sci Rep. 2015 Jan 29;5:8123. doi: 10.1038/srep08123
Epub:
Not Epub
Abstract:
Agr family includes three groups of genes, Ag1, Agr2 and Agr3, which encode the thioredoxin domain-containing secreted proteins...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Ivanova AS, Shandarin IN, Ermakova GV, Minin AA, Tereshina MB, Zaraisky AG. The secreted factor Ag1 missing in higher vertebrates regulates fins regeneration in Danio rerio. Sci Rep. 2015 Jan 29;5:8123. doi: 10.1038/srep08123.

Rapid screening of gene function by systemic delivery of morpholino oligonucleotides to live mouse embryos

Authors:
McClelland KS, Wainwright EN, Bowles J, Koopman P
Citation:
PLoS One. 2015 Jan 28;10(1):e0114932. doi: 10.1371/journal.pone.0114932. eCollection 2015
Epub:
Not Epub
Abstract:
Traditional gene targeting methods in mice are complex and time consuming, especially when conditional deletion methods are...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
McClelland KS, Wainwright EN, Bowles J, Koopman P. Rapid screening of gene function by systemic delivery of morpholino oligonucleotides to live mouse embryos. PLoS One. 2015 Jan 28;10(1):e0114932. doi: 10.1371/journal.pone.0114932. eCollection 2015.

Correction: Manipulation of Developing Juvenile Structures in Purple Sea Urchins (Strongylocentrotus purpuratus) by Morpholino Injection into Late Stage Larvae

Authors:
The PLOS ONE Staff
Citation:
PLoS One. 2015 Jan 27;10(1):e0117679. doi: 10.1371/journal.pone.0117679. eCollection 2015
Epub:
Not Epub
Abstract:
There is an error in Fig. 5, "Developing spine structures in S. purpuratus." Please see the corrected Fig. 5 here.
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
The PLOS ONE Staff. Correction: Manipulation of Developing Juvenile Structures in Purple Sea Urchins (Strongylocentrotus purpuratus) by Morpholino Injection into Late Stage Larvae. PLoS One. 2015 Jan 27;10(1):e0117679. doi: 10.1371/journal.pone.0117679. eCollection 2015.

A Feasible Approach to Evaluate the Relative Reactivity of NHS-Ester Activated Group with Primary Amine-Derivatized DNA Analogue and Non-Derivatized Impurity

Authors:
Dou S, Virostko J, Greiner DL, Powers AC, Liu G
Citation:
Nucleosides Nucleotides Nucleic Acids. 2015 Feb;34(2):69-78. doi: 10.1080/15257770.2014.958236
Epub:
Not Epub
Abstract:
Synthetic DNA analogues with improved stability are widely used in life science. The 3'and/or 5' equivalent...
Citation Extract:
Dou S, Virostko J, Greiner DL, Powers AC, Liu G. A Feasible Approach to Evaluate the Relative Reactivity of NHS-Ester Activated Group with Primary Amine-Derivatized DNA Analogue and Non-Derivatized Impurity. Nucleosides Nucleotides Nucleic Acids. 2015 Feb;34(2):69-78. doi: 10.1080/15257770.2014.958236.

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