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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
Inhibition of Jagged-mediated Notch signaling disrupts zebrafish biliary development and generates multi-organ defects compatible with an Alagille syndrome phenocopy.
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Citation:
Development. 2004 Nov;131(22):5753-66. Epub:
Not Epub Abstract:
The Alagille Syndrome (AGS) is a heritable disorder affecting the liver and other organs. Causative dominant mutations in human... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Lorent K, Yeo SY, Oda T, Chandrasekharappa S, Chitnis A, Matthews RP, Pack M.. Inhibition of Jagged-mediated Notch signaling disrupts zebrafish biliary development and generates multi-organ defects compatible with an Alagille syndrome phenocopy.. Development. 2004 Nov;131(22):5753-66.. |
Inhibition of neurogenesis by SRp38, a neuroD-regulated RNA-binding protein
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Citation:
Development. 2005 Apr;132(7):1511-23. Epub 2005 Feb 23 Epub:
Not Epub Abstract:
Although serine-arginine rich (SR) proteins have often been implicated in the positive regulation of splicing, recent studies... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Liu KJ, Harland RM. Inhibition of neurogenesis by SRp38, a neuroD-regulated RNA-binding protein. Development. 2005 Apr;132(7):1511-23. Epub 2005 Feb 23. |
K-ras/PI3K-Akt signaling is essential for zebrafish hematopoiesis and angiogenesis
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Citation:
PLoS ONE. 2008 Aug 6;3(8):e2850 Epub:
Not Epub Abstract:
The RAS small GTPases orchestrate multiple cellular processes. Studies on knock-out mice showed the essential and sufficient... Organism or Cell Type:
zebrafish Citation Extract: Liu L, Zhu S, Gong Z, Low BC. K-ras/PI3K-Akt signaling is essential for zebrafish hematopoiesis and angiogenesis. PLoS ONE. 2008 Aug 6;3(8):e2850. |
Kinetic Mechanisms in Morpholino-DNA Surface Hybridization
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Citation:
J. Am. Chem. Soc. 2011;[Epub ahead of print] DOI: 10.1021/ja202631b Epub:
Not Epub Abstract:
Morpholinos (MOs) are DNA analogues whose uncharged nature can bring fundamental advantages to surface hybridization... Delivery Method:
species. Advancement of MO-based diagnostics Organism or Cell Type:
however Citation Extract: Liu Y, Irving D, Qiao W, Ge D, Levicky R. Kinetic Mechanisms in Morpholino-DNA Surface Hybridization. J. Am. Chem. Soc. 2011;[Epub ahead of print] DOI: 10.1021/ja202631b. |
Knockdown of Leptin A Expression Dramatically Alters Zebrafish Development
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Citation:
Gen Comp Endocrinol. 2012;[Epub ahead of print] doi:10.1016/j.ygcen.2012.07.011 Epub:
Not Epub Abstract:
Using morpholino antisense oligonucleotide (MO) technology, we blocked leptin A or leptin receptor expression in embryonic... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu Q, Dalman M, Chen Y, Akhter M, Brahmandam S, Patel Y, Lowe J, Thakkar M, Gregory AV, Phelps D, Riley C, Londraville RL. Knockdown of Leptin A Expression Dramatically Alters Zebrafish Development. Gen Comp Endocrinol. 2012;[Epub ahead of print] doi:10.1016/j.ygcen.2012.07.011. |
Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis.
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Citation:
Dev Cell. 2003 Dec;5(6):903-14 Epub:
Not Epub Abstract:
Mechanisms underlying the multiple developmental defects observed in Fanconi anemia (FA) patients are not well defined. We have... Delivery Method:
microinjection in embryos, Special Delivery in culture Organism or Cell Type:
Zebrafish embryos and cultured zebrafish fibroblast AB9 cells Citation Extract: Liu TX, Howlett NG, Deng M, Langenau DM, Hsu K, Rhodes J, Kanki JP, D'Andrea AD, Look AT. Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis.. Dev Cell. 2003 Dec;5(6):903-14. |
Leukocyte tyrosine kinase functions in pigment cell development
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Citation:
PLoS Genet. 2008 Mar 7;4(3):e1000026 Epub:
Not Epub Abstract:
A fundamental problem in developmental biology concerns how multipotent precursors choose specific fates. Neural crest cells (... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Lopes SS, Yang X, Müller J, Carney TJ, McAdow AR, Rauch GJ, Jacoby AS, Hurst LD, Delfino-Machín M, Haffter P, Geisler R, Johnson SL, Ward A, Kelsh RN. Leukocyte tyrosine kinase functions in pigment cell development. PLoS Genet. 2008 Mar 7;4(3):e1000026. |
Lysophosphatidic acid signaling controls cortical actin assembly and cytoarchitecture in Xenopus embryos
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Citation:
Development. 2005 Feb;132(4):805-16. Epub 2005 Jan 19 Epub:
Not Epub Abstract:
The mechanisms that control shape and rigidity of early embryos are not well understood, and yet are required for all embryonic... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Lloyd B, Tao Q, Lang S, Wylie C. Lysophosphatidic acid signaling controls cortical actin assembly and cytoarchitecture in Xenopus embryos. Development. 2005 Feb;132(4):805-16. Epub 2005 Jan 19. |
MicroRNA-206 regulates cell movements during zebrafish gastrulation by targeting prickle1a and regulating JNK2 phosphorylation
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Citation:
Mol Cell Biol. 2012 May 21. [Epub ahead of print] Epub:
Not Epub Abstract:
During vertebrate gastrulation, both concurrent inductive events and cell movements are required for axis formation.... Organism or Cell Type:
zebrafish Citation Extract: Liu X, Ning G, Meng A, Wang Q. MicroRNA-206 regulates cell movements during zebrafish gastrulation by targeting prickle1a and regulating JNK2 phosphorylation. Mol Cell Biol. 2012 May 21. [Epub ahead of print]. |
MIM regulates vertebrate neural tube closure
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Citation:
Development. 2011 May;138(10):2035-47. Epub 2011 Apr 6 Epub:
Not Epub Abstract:
Neural tube closure is a critical morphogenetic event that is regulated by dynamic changes in cell shape and behavior. Although... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Liu W, Komiya Y, Mezzacappa C, Khadka DK, Runnels L, Habas R. MIM regulates vertebrate neural tube closure. Development. 2011 May;138(10):2035-47. Epub 2011 Apr 6. |