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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12067 scientific papers returned from the database with the search filters currently being used below.

A steric blocker of translation elongation inhibits IGF-1R expression and cell transformation

Authors:
Lecosnier S, Cordier C, Simon P, François JC, Saison-Behmoaras TE
Citation:
FASEB J. 2011 Mar 14. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The insulin-like growth factor 1 receptor (IGF-1R) is involved in transformation, survival, mitogenesis and differentiation. It...
Citation Extract:
Lecosnier S, Cordier C, Simon P, François JC, Saison-Behmoaras TE. A steric blocker of translation elongation inhibits IGF-1R expression and cell transformation. FASEB J. 2011 Mar 14. [Epub ahead of print].

A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis

Authors:
Leacock SW, Basse AN, Chandler GL, Kirk AM, Rakheja D, Amatruda JF
Citation:
Dis Model Mech. 2012 Jan;5(1):95-106. Epub 2011 Oct 6
Epub:
Not Epub
Abstract:
Ewing’s sarcoma, a malignant bone tumor of children and young adults, is a member of the small-round-blue-cell tumor family....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Leacock SW, Basse AN, Chandler GL, Kirk AM, Rakheja D, Amatruda JF. A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis. Dis Model Mech. 2012 Jan;5(1):95-106. Epub 2011 Oct 6.

Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis

Authors:
Larrivee B, Freitas C, Trombe M, Lv X, Delafarge B, Yuan L, Bouvree K, Breant C, Del Toro R, Brechot N, Germain S, Bono F, Dol F, Claes F, Fischer C, Autiero M, Thomas JL, Carmeliet P, Tessier-Lavigne M, Eichmann A
Citation:
Genes Dev. 2007 Oct 1;21(19):2433-47
Epub:
Not Epub
Abstract:
Netrins are secreted molecules with roles in axonal growth and angiogenesis. The Netrin receptor UNC5B is required during...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Larrivee B, Freitas C, Trombe M, Lv X, Delafarge B, Yuan L, Bouvree K, Breant C, Del Toro R, Brechot N, Germain S, Bono F, Dol F, Claes F, Fischer C, Autiero M, Thomas JL, Carmeliet P, Tessier-Lavigne M, Eichmann A. Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis. Genes Dev. 2007 Oct 1;21(19):2433-47.

Ajuba LIM proteins are snail/slug corepressors required for neural crest development in Xenopus

Authors:
Langer EM, Feng Y, Zhaoyuan H, Rauscher FJ 3rd, Kroll KL, Longmore GD
Citation:
Dev Cell. 2008 Mar;14(3):424-36
Epub:
Not Epub
Abstract:
Snail family transcriptional repressors regulate epithelial mesenchymal transitions during physiological and pathological...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Langer EM, Feng Y, Zhaoyuan H, Rauscher FJ 3rd, Kroll KL, Longmore GD. Ajuba LIM proteins are snail/slug corepressors required for neural crest development in Xenopus. Dev Cell. 2008 Mar;14(3):424-36.

Alternative Splicing of sept9a and sept9b in Zebrafish Produces Multiple mRNA Transcripts Expressed Throughout Development

Authors:
Landsverk ML, Weiser DC, Hannibal MC, Kimelman D
Citation:
PLoS One. 2010 May 19;5(5):e10712
Epub:
Not Epub
Abstract:
BACKGROUND: Septins are involved in a number of cellular processes including cytokinesis and organization of the cytoskeleton....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Landsverk ML, Weiser DC, Hannibal MC, Kimelman D. Alternative Splicing of sept9a and sept9b in Zebrafish Produces Multiple mRNA Transcripts Expressed Throughout Development. PLoS One. 2010 May 19;5(5):e10712.

Analysis of 14-3-3 family member function in Xenopus embryos by microinjection of antisense morpholino oligos

Authors:
Lau JM, Muslin AJ
Citation:
Methods Mol Biol. 2009;518:1-11
Epub:
Not Epub
Abstract:
The 14-3-3 intracellular phosphoserine/threonine-binding proteins are adapter molecules that regulate signal transduction, cell...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Lau JM, Muslin AJ. Analysis of 14-3-3 family member function in Xenopus embryos by microinjection of antisense morpholino oligos. Methods Mol Biol. 2009;518:1-11.

Cell penetrating peptide conjugates of steric block oligonucleotides

Authors:
Lebleu B, Moulton HM, Abes R, Ivanova GD, Abes S, Stein DA, Iversen PL, Arzumanov AA, Gait MJ
Citation:
Adv Drug Deliv Rev. 2008 Mar 1;60(4-5):517-29. Epub 2007 Oct 22.
Epub:
Not Epub
Abstract:
Charge neutral steric block oligonucleotide analogues, such as peptide nucleic acids (PNA) or phosphorodiamidate morpholino...
Delivery Method:
peptide-coupled
Organism or Cell Type:
various
Citation Extract:
Lebleu B, Moulton HM, Abes R, Ivanova GD, Abes S, Stein DA, Iversen PL, Arzumanov AA, Gait MJ. Cell penetrating peptide conjugates of steric block oligonucleotides. Adv Drug Deliv Rev. 2008 Mar 1;60(4-5):517-29. Epub 2007 Oct 22..

Circulating Bmp10 acts through endothelial Alk1 to mediate flow-dependent arterial quiescence

Authors:
Laux DW, Young S, Donovan JP, Mansfield CJ, Upton PD, Roman BL
Citation:
Development. 2013;140:3403-12. [Epub ahead of print] doi:10.1242/dev.095307
Epub:
Not Epub
Abstract:
Blood flow plays crucial roles in vascular development, remodeling and homeostasis, but the molecular pathways required for...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Laux DW, Young S, Donovan JP, Mansfield CJ, Upton PD, Roman BL. Circulating Bmp10 acts through endothelial Alk1 to mediate flow-dependent arterial quiescence. Development. 2013;140:3403-12. [Epub ahead of print] doi:10.1242/dev.095307.

Conserved Regulation of p53 Network Dosage by MicroRNA–125b Occurs through Evolving miRNA–Target Gene Pairs

Authors:
Le MTN, Shyh-Chang N, Khaw SL, Chin L, Teh C, Tay J, O'Day E, Korzh V, Yang H, Lal A, Lieberman J, Lodish HF, Lim B
Citation:
PLoS Genet. 2011;7(9): e1002242. doi:10.1371/journal.pgen.1002242
Epub:
Not Epub
Abstract:
MicroRNAs regulate networks of genes to orchestrate cellular functions. MiR-125b, the vertebrate homologue of the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Le MTN, Shyh-Chang N, Khaw SL, Chin L, Teh C, Tay J, O'Day E, Korzh V, Yang H, Lal A, Lieberman J, Lodish HF, Lim B. Conserved Regulation of p53 Network Dosage by MicroRNA–125b Occurs through Evolving miRNA–Target Gene Pairs. PLoS Genet. 2011;7(9): e1002242. doi:10.1371/journal.pgen.1002242.

Defective adult oligodendrocyte and Schwann cell development, pigment pattern, and craniofacial morphology in puma mutant zebrafish having an alpha tubulin mutation

Authors:
Larson TA, Gordon TN, Lau HE, Parichy DM
Citation:
Dev Biol. 2010 Oct 15;346(2):296-309. Epub 2010 Aug 5
Epub:
Not Epub
Abstract:
The processes of myelination remain incompletely understood but are of profound biomedical importance owing to the several...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Larson TA, Gordon TN, Lau HE, Parichy DM. Defective adult oligodendrocyte and Schwann cell development, pigment pattern, and craniofacial morphology in puma mutant zebrafish having an alpha tubulin mutation. Dev Biol. 2010 Oct 15;346(2):296-309. Epub 2010 Aug 5.

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