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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9743 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Pax2/8 act redundantly to specify glycinergic and GABAergic fates of multiple spinal interneurons

Authors:
Batista MF, Lewis KE
Citation:
Dev Biol. 2008 Nov 1;323(1):88-97. Epub 2008 Aug 18
Abstract:
The spinal cord contains several distinct classes of neurons but it is still unclear how many of the functional characteristics...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Batista MF, Lewis KE. Pax2/8 act redundantly to specify glycinergic and GABAergic fates of multiple spinal interneurons. Dev Biol. 2008 Nov 1;323(1):88-97. Epub 2008 Aug 18.

Perturbation of rRNA synthesis in the bap28 mutation leads to apoptosis mediated by p53 in the zebrafish central nervous system

Authors:
Azuma M, Toyama R, Laver E, Dawid IB
Citation:
J Biol Chem. 2006 May 12;281(19):13309-16. Epub 2006 Mar 10
Abstract:
Zebrafish is a powerful vertebrate model system for using forward genetics to elucidate mechanisms of early development. We...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Azuma M, Toyama R, Laver E, Dawid IB. Perturbation of rRNA synthesis in the bap28 mutation leads to apoptosis mediated by p53 in the zebrafish central nervous system. J Biol Chem. 2006 May 12;281(19):13309-16. Epub 2006 Mar 10.

Phosphorodiamidate Morpholino Antisense Oligomers Inhibit Expression of Human Cytochrome P450 3A4 and Alter Selected Drug Metabolism

Authors:
Arora V, Cate ML, Ghosh C, Iversen PL
Citation:
Drug Metab Dispos. 2002 Jul 1;30(7):757-762
Abstract:
Antisense phosphorodiamidate morpholino oligomers (PMO) inhibit targeted gene expression by preventing ribosomal assembly, thus...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: hepatocytes (human primary cells), Caco-2/h3A4 cells
Citation Extract:
Arora V, Cate ML, Ghosh C, Iversen PL. Phosphorodiamidate Morpholino Antisense Oligomers Inhibit Expression of Human Cytochrome P450 3A4 and Alter Selected Drug Metabolism. Drug Metab Dispos. 2002 Jul 1;30(7):757-762.

Proliferation of embryonic cardiomyocytes in zebrafish requires the sodium channel scn5Lab

Authors:
Bennett J, Stroud D, Becker J, Roden D
Citation:
Genesis. 2013 May 3. doi: 10.1002/dvg.22400. [Epub ahead of print]
Abstract:
In mice, homozygous deletion of the cardiac sodium channel Scn5a results in defects in cardiac morphology and embryonic death...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bennett J, Stroud D, Becker J, Roden D. Proliferation of embryonic cardiomyocytes in zebrafish requires the sodium channel scn5Lab. Genesis. 2013 May 3. doi: 10.1002/dvg.22400. [Epub ahead of print].

Protein kinase D2 is a crucial regulator of tumour cell-endothelial cell communication in gastrointestinal tumours

Authors:
Azoitei N, Pusapati GV, Kleger A, Möller P, Küfer R, Genze F, Wagner M, van Lint J, Carmeliet P, Adler G, Seufferlein T
Citation:
Gut. 2010 Aug 23. [Epub ahead of print]
Abstract:
Background Tumour angiogenesis is crucially dependent on the communication between the tumour and the associated endothelium....
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice, NMRI nu/nu
Citation Extract:
Azoitei N, Pusapati GV, Kleger A, Möller P, Küfer R, Genze F, Wagner M, van Lint J, Carmeliet P, Adler G, Seufferlein T. Protein kinase D2 is a crucial regulator of tumour cell-endothelial cell communication in gastrointestinal tumours. Gut. 2010 Aug 23. [Epub ahead of print].

Protein O-mannosylation is necessary for normal embryonic development in zebrafish

Authors:
Avsar-Ban E, Ishikawa H, Manya H, Watanabe M, Akiyama S, Miyake H, Endo T, Tamaru Y
Citation:
Glycobiology. 2010 May 10. [Epub ahead of print]
Abstract:
Two distinct cDNAs corresponding to two zebrafish protein O-mannosyltransferase genes, zPOMT1 and zPOMT2, were cloned from...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Avsar-Ban E, Ishikawa H, Manya H, Watanabe M, Akiyama S, Miyake H, Endo T, Tamaru Y. Protein O-mannosylation is necessary for normal embryonic development in zebrafish. Glycobiology. 2010 May 10. [Epub ahead of print].

Rat glomerular mesangial cells require laminin-9 to migrate in response to insulin-like growth factor binding protein-5

Authors:
Berfield AK, Hansen K, Abrass CK
Citation:
Am J Physiol Cell Physiol. 2006 Oct;291(4):C589-99. Epub 2006 May 3.
Abstract:
Temporal and spatial differences in extracellular matrix play critical roles in cell proliferation, differentiation and...
Delivery Method:
Special Delivery
Organism or Cell Type:
Cell culture: Rat glomerular mesangial cells
Citation Extract:
Berfield AK, Hansen K, Abrass CK. Rat glomerular mesangial cells require laminin-9 to migrate in response to insulin-like growth factor binding protein-5. Am J Physiol Cell Physiol. 2006 Oct;291(4):C589-99. Epub 2006 May 3..

Redirection of drug metabolism using antisense technology

Authors:
Arora V, Iversen PL
Citation:
Curr Opin Mol Ther. 2001 Jun;3(3):249-57. Review.
Abstract:
The cytochrome P450 (CYP) family is the most catalytically versatile component of the phase I oxidation metabolic pathway and...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Arora V, Iversen PL. Redirection of drug metabolism using antisense technology. Curr Opin Mol Ther. 2001 Jun;3(3):249-57. Review..

Responses of Human Cells to PAH-Induced DNA Damage

Authors:
Baird WM, Hooven LA, Mahadevan B, Luch A, Seidel A, Iversen PL
Citation:
Polycyclic Aromatic Compounds . 2002; 22(3-4): 771 - 780
Abstract:
Benzo[a]pyrene (B[a]P) and dibenzo[a,l]pyrene (DB[a,l]P) induce cytochrome P450 (CYP) CYP1A1 and CYP1B1, which metabolize these...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: human MCF-7 cells
Citation Extract:
Baird WM, Hooven LA, Mahadevan B, Luch A, Seidel A, Iversen PL. Responses of Human Cells to PAH-Induced DNA Damage. Polycyclic Aromatic Compounds . 2002; 22(3-4): 771 - 780.

roundabout4 is essential for angiogenesis in vivo

Authors:
Bedell VM, Yeo SY, Park KW, Chung J, Seth P, Shivalingappa V, Zhao J, Obara T, Sukhatme VP, Drummond IA, Li DY, Ramchandran R
Citation:
Proc Natl Acad Sci U S A. 2005 May 3;102(18):6373-8. Epub 2005 Apr 22
Abstract:
Stereotypical patterns of vascular and neuronal networks suggest that specific genetic programs tightly control path...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bedell VM, Yeo SY, Park KW, Chung J, Seth P, Shivalingappa V, Zhao J, Obara T, Sukhatme VP, Drummond IA, Li DY, Ramchandran R. roundabout4 is essential for angiogenesis in vivo. Proc Natl Acad Sci U S A. 2005 May 3;102(18):6373-8. Epub 2005 Apr 22.

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